Article
Family Studies
Vincent J. Palusci, Patricia G. Schnitzer, Abigael Collier
Summary: This study aims to understand child maltreatment fatalities among older children. It was found that older children had higher proportions of non-Hispanic white, chronic disease or disability, school problems, and mental health issues. Neglect contributed to the majority of child suicides, reaching 80%.
CHILD ABUSE & NEGLECT
(2023)
Article
Family Studies
Nichole L. Michaels, Megan M. Letson
Summary: This study aimed to epidemiologically describe child maltreatment-related fatalities among children in the United States aged 5-17 years old. The results showed that although child maltreatment deaths are less common among older children and adolescents compared to younger children, these fatalities have unique characteristics that should be considered when developing prevention strategies.
CHILD ABUSE & NEGLECT
(2021)
Article
Public, Environmental & Occupational Health
Ahmed Mahmoud Fouad, Shaimaa A. A. M. Amer, Yasser Omar Abdellatif, Sally Fawzy Elotla
Summary: Egypt has strict international regulations on child labor, but still struggles with a high prevalence and associated health risks of child labor. This study aimed to identify the prevalence and determinants of work-related injuries among working children in Egypt. The results showed a high prevalence of work-related injuries, with the majority being superficial wounds. Gender, age of starting work, type of economic activity, workplace type, work hours per week, and exposure to hazards were identified as the main determinants of work-related injuries.
Article
Environmental Sciences
Pengfei Li, Jingyi Wu, Ruohan Wang, Hengyi Liu, Tong Zhu, Tao Xue
Summary: This study analyzed the association between long-term exposure to PM2.5 from different sources and under-five deaths (U5Ds) in vulnerable children in low- and middle-income countries (LMICs). The results showed that PM2.5 from desert dust, solid biofuel combustion, and open fires had the greatest impact on child health. Public health interventions should consider the source profile of PM2.5 to effectively protect child health.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Cardiac & Cardiovascular Systems
Soren K. Nielsen, Frederikke G. Hansen, Torsten B. Rasmussen, Thomas Fischer, Jens F. Lassen, Trine Madsen, Dorthe S. Moller, Ib C. Klausen, John B. Brodersen, Morten S. K. Jensen, Jens Mogensen
Summary: Family screening of relatives of HCM index patients with a normal genetic investigation revealed a small number of affected relatives with a favorable prognosis.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Review
Endocrinology & Metabolism
Natalie M. Garza, Abhinav B. Swaminathan, Krishna P. Maremanda, Mohammad Zulki Fli, Vishal M. Gohil
Summary: Copper is an essential micronutrient that plays a crucial role in mitochondrial energy metabolism. Copper enters cells through transporters and is distributed to cuproenzymes by chaperones. Mutations in copper transporters and chaperones disrupt copper homeostasis in mitochondria, leading to genetic disorders. Elesclomol, a copper ionophore, shows therapeutic potential for copper deficiency disorders.
TRENDS IN ENDOCRINOLOGY AND METABOLISM
(2023)
Article
Family Studies
Sara Scardera, Rachel Langevin, Delphine Collin-Vezina, Maude Comtois Cabana, Snehal M. Pinto Pereira, Sylvana Cote, Isabelle Ouellet-Morin, Marie-Claude Geoffroy
Summary: This study developed a prospective index of child maltreatment through long-term observation from 5 months to 17 years, and compared it with retrospective reports. The study found weak but significant concordance between prospective and retrospective reports, highlighting the importance of both measures.
CHILD ABUSE & NEGLECT
(2023)
Article
Public, Environmental & Occupational Health
Omid Dadras, Mohammadsediq Hazratzai, Fateme Dadras
Summary: This study used data from the 2015 Afghanistan demographic health survey to examine the impact of child marriage on child mortality and morbidity. The findings showed a higher likelihood of neonatal mortality and infant mortality among births to women married at a younger age, but this association disappeared after adjustment for socioeconomic and structural inequalities. The study emphasizes the importance of providing adequate antenatal care for young brides and advocating for gender equality to prevent child mortality in Afghanistan.
Article
Environmental Sciences
Hao Zheng, QingQing Wang, Jianguan Fu, Zhen Ding, Jian Cheng, Zhiwei Xu, Yan Xu, Yankai Xia
Summary: Understanding the geographical distribution of temperature's association with childhood diarrhea is important for developing effective localized prevention practices. This study examines the variation in temperature's effects on Class C Other Infectious Diarrhea (OID) among children in Jiangsu Province, China, including thresholds, lag effects, and attributable fraction (AF). The study identifies specific temperature indicators and evaluates the AF, showing variations between cities and the influence of latitude and economic status. The findings emphasize the need for localized clinical and public health practices to reduce childhood diarrhea incidence.
ENVIRONMENTAL RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Silke Fernandes, Marcia Pinto, Leticia Barros, Maria Elisabeth Lopes Moreira, Thalia Velho Barreto de Araujo, Tereza Maciel Lyra, Sandra Valongueiro, Mireia Jofre-Bonet, Hannah Kuper
Summary: The economic burden of children with CZS in Brazil is estimated in this study, and it is found that the cost for severe CZS is significantly higher than moderate CZS and without CZS. The government bears the majority of the economic burden for severe CZS, but a lower proportion for moderate CZS.
Article
Genetics & Heredity
Amelle Shillington, Martine Lamy, Kelli C. Dominick, Michael Sorter, Craig A. Erickson, Robert Hopkin
Summary: Neurodevelopmental disorders often face barriers in accessing clinical genetics evaluation and testing. However, the establishment of a collaborative psychiatric-genetics consultation service and outpatient clinic has significantly improved care delivery for patients with these disorders. Two years after its launch, this pilot program has shown improved access to genetics evaluation, shorter wait times, and decreased loss to follow-up. Importantly, new genetic diagnoses have resulted in changes in medical care for the majority of patients.
FRONTIERS IN GENETICS
(2022)
Article
Clinical Neurology
Leon Beyer, Hannah Stocker, Dan Rujescu, Bernd Holleczek, Julia Stockmann, Andreas Nabers, Hermann Brenner, Klaus Gerwert
Summary: This study found that certain blood-based biomarkers are associated with clinical risk of Alzheimer's disease in a long-term community cohort. A beta misfolding and GFAP concentration were particularly important and accurate predictors of AD risk.
ALZHEIMERS & DEMENTIA
(2023)
Article
Biochemistry & Molecular Biology
Hang Zhu, Ying Tan, Wenjun Du, Yang Li, Sam Toan, David Mui, Feng Tian, Hao Zhou
Summary: In the context of cardiac ischemia-reperfusion injury, PGAM5 plays a role in driving cardiomyocyte necroptosis by regulating mitochondrial quality control, while also suppressing necroptosis without preventing apoptosis, leading to improved heart function and reduced inflammation response.
Review
Biochemistry & Molecular Biology
Vicente Javier Clemente-Suarez, Alexandra Martin-Rodriguez, Rodrigo Yanez-Sepulveda, Jose Francisco Tornero-Aguilera
Summary: Mitochondrial dysfunction is a common feature of various diseases, and mitochondrial transfer has emerged as a potential therapeutic approach for restoring mitochondrial function. This review summarizes the current understanding of mitochondrial transfer, its mechanisms, therapeutic applications, and impact on cell death pathways. The future directions and challenges in using mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment are also discussed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Respiratory System
Jinhong Wu, Hao Zhang, Yongsheng Shi, Jinrong Wang, Yuling Han, Qiaoling Zhang, Ning Wang, Sha Liu, Yuehua Zhang, Huifen Zi, Fei Wang, Aihong Liu, Yuxin Song, ChunMei Jia, Yong Feng, Quanhua Liu, Liya Wan, Minghong Ji, Zhen Long, Jianfeng Huang, Li Liu, Yun Sun, Suping Tang, Xiaoyan Dong, Xiaojian Zhou, Wenhui Jiang, Li Shen, Haohua Jiang
Summary: This study aimed to establish the predicted value of pulmonary function determined by impulse oscillometry (IOS) in Chinese children (4-17 years old). The study analyzed the IOS parameters of 6270 healthy children and found that these parameters were related to height, age, and weight. A predicted value equation was established based on these factors. Compared to other reference equations, this equation was more suitable for Chinese children.
RESPIRATORY RESEARCH
(2022)
