Article
Engineering, Multidisciplinary
Khalid I. A. Ahmed, Haroon D. S. Adam, M. Y. Youssif, Sayed Saber
Summary: In this paper, a fractal-fractional-order model of glucose-insulin interaction based on IVGT is proposed and analyzed both qualitatively and numerically, with consistent analytical and simulation results.
ALEXANDRIA ENGINEERING JOURNAL
(2023)
Article
Multidisciplinary Sciences
Aaron P. Owji, Jiali Wang, Alec Kittredge, Zada Clark, Yu Zhang, Wayne A. Hendrickson, Tingting Yang
Summary: This study reports the cryo-EM structures of human Bestrophin, revealing the molecular mechanisms of its function. The C-terminal auto-inhibitory segment plays a crucial role in regulating the opening of the channel, highlighting the significance of this finding in understanding the functions of the Bestrophin family.
NATURE COMMUNICATIONS
(2022)
Article
Energy & Fuels
Maria Cortazar, Jon Alvarez, Leire Olazar, Laura Santamaria, Gartzen Lopez, Heidi Isabel Villafan-Vidales, Asier Asueta, Martin Olazar
Summary: The performance of olivine, dolomite, and gamma-alumina primary catalysts was evaluated in continuous tar elimination process. Iron incorporation improved their catalytic activity, with Fe/Al2O3 exhibiting the highest conversion and stability.
Article
Chemistry, Multidisciplinary
Minoru Kurisu, Ryosuke Katayama, Yuka Sakuma, Toshihiro Kawakatsu, Peter Walde, Masayuki Imai
Summary: In this study, a synthetic minimal cell consisting of energy production, information polymer synthesis, and vesicle reproduction is synthesized. By converting supplied ingredients to energy currencies, the synthesis of an information polymer is triggered, with the vesicle membrane acting as a template. The information polymer promotes membrane growth, allowing the vesicles to undergo recursive reproduction.
COMMUNICATIONS CHEMISTRY
(2023)
Article
Thermodynamics
Yingying Liu, Sha Chen, Kejun Jiang, Wendkuuni Steve-Harold Kaghembega
Summary: Cities play critical roles in achieving carbon-neutrality. The pathways and challenges to carbon-neutrality differ among different city types. The industry sector is always the key sector, and optimizing production processes and reducing surplus output are crucial. Some cities can achieve carbon-neutrality by implementing carbon capture and storage technology by 2049 or 2050. Challenges include reducing CO2 emissions from transportation and buildings, as well as promoting electrification and the use of zero-carbon energy.
Article
Chemistry, Physical
Niloufar Goudarzi, Kourosh Jafarzadeh, Abolfazl Kashi, Hadiseh Abassi
Summary: A novel mechanism for the deactivation of Pt/Nb anodes in the electrochemical oxidation of chlorate-containing solutions has been presented in this research. The effect of electrolyte temperature on this mechanism has also been investigated. The samples were exposed to the accelerated life test at different temperatures, and their electrochemical behavior and morphology changes were studied. The results showed that the highest corrosion resistance and electrocatalytic activity of the anode were achieved at 35°C, while deactivation occurred at 65°C due to the dissolution of the platinum coating and subsequent substrate passivation.
Article
Multidisciplinary Sciences
Danyang Zhang, Jake F. Watson, Peter M. Matthews, Ondrej Cais, Ingo H. Greger
Summary: This study reveals the structure and active states of AMPAR complexes, demonstrating that TARP-gamma 8 and CNIH2 affect the gating regulation of AMPARs by binding to specific regions of the receptor, thereby promoting the transition to the active-state conformation.
Article
Environmental Studies
Yu Ding, Hongbo Duan, Xu Tang, Kaipeng Ren, Zheqi Yang, Zhixuan Lan, Shizhang Liu
Summary: China's carbon neutrality target by 2060 would require significant reductions in oil consumption, primary energy demand, and carbon emissions by more than 79%, 32%, and 98% respectively. Through multi-model comparisons, it was found that China's oil consumption is projected to gradually increase to 941.32 million tons in 2060 under the reference scenario, peak at 780.28 million tons around 2030 under the 2 degrees C scenario, and experience a sharp reduction to 190.17 million tons in 2060 under the 1.5 degrees C scenario. This research provides reliable assessments for China's oil consumption, energy demand, and carbon emissions, and can contribute to addressing climate change domestically.
ENVIRONMENTAL IMPACT ASSESSMENT REVIEW
(2023)
Review
Neurosciences
Angeleen Fleming, Mathieu Bourdenx, Motoki Fujimaki, Cansu Karabiyik, Gregory J. Krause, Ana Lopez, Claudia Puri, Aurora Scrivo, John Skidmore, Sung Min Son, Eleanna Stamatakou, Lidia Wrobel, Ye Zhu, Ana Maria Cuervo, David C. Rubinsztein
Summary: Autophagy is crucial for maintaining cellular homeostasis by degrading proteins and organelles. The nervous system is particularly dependent on these pathways, which may become less effective with age. Autophagy pathways play a protective role in neurodegenerative diseases and are also linked to different types of programmed cell death.
Review
Chemistry, Physical
Xingyuan Gao, Yili Wen, Rui Tan, Haiqing Huang, Sibudjing Kawi
Summary: In this review, the issue of catalyst deactivation in thermo-catalytic hydrogen production from methane is discussed, and six modification strategies to achieve a robust catalyst are proposed. The reaction mechanisms of seven methane-involved reactions and three deactivation mechanisms are illustrated. Furthermore, a critical analysis of the synthesis-structure-performance relationship is provided, and conclusive remarks and prospects are proposed.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Chemistry, Physical
Wenhuan Huang, Xiaolong Zhang, Jing Chen, Baicheng Zhang, Biao Chen, Guoqing Zhang
Summary: Photopolymerization reactions have advantages over traditional thermal polymerization, and the compositionally pure polymers with one repeating unit are desirable. In this study, polyDMA (PDMA) homopolymers without heterogeneous end groups were produced using a commercially available monomer N,N-dimethyl acrylamide (DMA) and a naphthalimide. The UV-activated complex formed by DMA and naphthalimide initiates the polymerization, which can be switched on/off by light/dark conditions.
Article
Chemistry, Physical
Aleksei N. Marianov, Alena S. Kochubei, Tanglaw Roman, Oliver J. Conquest, Catherine Stampfl, Yijiao Jiang
Summary: This study investigates the stability mechanism of Co porphyrin-based catalysts during CO2 reduction and identifies the main reasons for gradual activity loss, providing insights into improving catalyst stability.
Article
Chemistry, Analytical
Katharina Woehrl, Yash Kotak, Christian Geisbauer, Sonke Barra, Gudrun Wilhelm, Gerhard Schneider, Hans-Georg Schweiger
Summary: The increasing deployment of battery-powered electric vehicles in the market has led to a growing need for the safe deactivation and recycling of batteries. Different deactivation methods for lithium-ion cells are used, including electrical discharging and deactivation with liquids. In this experimental research, the use of calcium chloride (CaCl2) salt as a deactivation medium is compared to regular Tap Water and Demineralized Water to analyze its performance and safety. The results show that cells deactivated in CaCl2 solution did not show any signs of Fluoride ions, making it a potential optimal solution for rapid deactivation of cells.
Article
Engineering, Chemical
Kaixuan Chen, Yankai Cao, Huihong Zhu, Hailong Ge, Tao Yang, Zhiming Zhou, Zhenmin Cheng
Summary: Residue catalytic hydrogenation experiments were conducted in a two-stage fixed-bed reactor system to mimic industrial operation. Coke deposition was found to be the main cause of initial stage deactivation, while the deposition of metal sulfides led to slow deactivation in the middle stage. A deactivation model considering catalyst activity as a function of time on stream (TOS) was proposed and applied to the reaction. Deactivation parameters for different catalysts were obtained by fitting experimental data. Multi-bed hydrogenation was shown to effectively increase catalyst life.
Article
Biochemistry & Molecular Biology
Yixuan Lei, Panyu Fei, Bin Song, Wenjia Shi, Cheng Luo, Dahai Luo, Dan Li, Wei Chen, Jie Zheng
Summary: This study investigated how subtle conformational changes in the helicase insertion domain (HEL2i) of RIG-I can impair ATPase and RNA proofreading activities, leading to increased immunopathy. The findings highlight the importance of HEL2i as a checkpoint in controlling antiviral innate immunity and autoimmune diseases.
NUCLEIC ACIDS RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Andreas Missner, Philipp Kuegler, Sapar M. Saparov, Klaus Sommer, John C. Mathai, Mark L. Zeidel, Peter Pohl
JOURNAL OF BIOLOGICAL CHEMISTRY
(2008)
Article
Biochemistry & Molecular Biology
Liudmila Erokhova, Andreas Horner, Philipp Kuegler, Peter Pohl
JOURNAL OF BIOLOGICAL CHEMISTRY
(2011)
Article
Biology
Philipp Kuegler, Wei Yang
JOURNAL OF MATHEMATICAL BIOLOGY
(2014)
Article
Physiology
S. Beyl, P. Kuegler, A. Hohaus, K. Depil, S. Hering, E. Timin
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
(2014)
Article
Multidisciplinary Sciences
Philipp Kuegler
Letter
Multidisciplinary Sciences
Andreas Missner, Philipp Kuegler, Yuri N. Antonenko, Peter Pohl
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2008)
Article
Multidisciplinary Sciences
John C. Mathai, Andreas Missner, Philipp Kuegler, Sapar M. Saparov, Mark L. Zeidel, John K. Lee, Peter Pohl
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2009)
Article
Mathematical & Computational Biology
Clemens A. Zarzer, Martin G. Puchinger, Gottfried Koehler, Philipp Kuegler
THEORETICAL BIOLOGY AND MEDICAL MODELLING
(2013)
Article
Multidisciplinary Sciences
Philipp Kuegler, Andre H. Erhardt, M. A. K. Bulelzai
Article
Mathematics, Applied
Nagaiah Chamakuri, Philipp Kuegler
APPLIED MATHEMATICS AND COMPUTATION
(2020)
Meeting Abstract
Biophysics
John C. Mathai, Andreas Missner, Philipp Kuegler, Sapar M. Saparov, Mark L. Zeidel, John K. Lee, Peter Pohl
BIOPHYSICAL JOURNAL
(2010)