期刊
JOURNAL OF GASTROINTESTINAL SURGERY
卷 15, 期 10, 页码 1789-1797出版社
SPRINGER
DOI: 10.1007/s11605-011-1498-6
关键词
Pancreaticoduodenectomy; Delayed gastric emptying; Stapled reconstruction; Hand-sewn reconstruction
资金
- Ministry of Health and Welfare of Japan
Background Delayed gastric emptying (DGE) is one of the most troublesome complications after pancreaticoduodenectomy (PD). Methods Between 2004 and 2009, 387 patients underwent PD and of these, 302 patients (78%) underwent pylorus-preserving PD. The stapled reconstruction of duodeno- or gastrojejunostomy was introduced in 2006, and 70 patients (18%) underwent stapled Roux-en-Y reconstruction. Postoperative DGE was defined based on the International Study Group on Pancreatic Surgery classification, and grade B or C DGE was considered to be clinically relevant. Risk factors for DGE were evaluated using univariate and multivariate analyses. Results Four patients died in the hospital (1.0%). Postoperative DGE was found in 70 patients (18%). DGE was less frequently seen in stapled reconstruction than in hand-sewn reconstruction (7.2% vs. 21%, P < 0.001), and in single-layer anastomosis than in double-layer anastomosis (12% vs. 24%, P = 0.02). The multivariate logistic regression analysis revealed that the independent risk factors for DGE were postoperative pancreatic fistula (risk ratio [RR] 2.4, P = 0.002), hand-sewn reconstruction (RR 2.9, P = 0.03) and male (RR 2.2, P = 0.02). Conclusion The method of alimentary reconstruction affected the occurrence of DGE. The incidence of DGE was less in stapled reconstruction than in hand-sewn reconstruction.
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