Article
Virology
Luiz Henrique Ferraz Demarchi, Larissa Melo Bandeira, Deborah Ledesma Taira, Marina Castilhos Souza Umaki Zardin, Mary Luizia Ibanhes, Ana Olivia Pascoto Esposito, Larissa Domingues Castilho de Arruda, Crhistinne Cavalheiro Maymone Goncalves, Sabrina Moreira dos Santos Weis-Torres, Gabriela Alves Cesar, Rivaldo Venancio da Cunha, Tayana Serpa Ortiz Tanaka, Marco Antonio Moreira Puga, Grazielli Rocha de Rezende, Roberta Barbosa Lopes, Silvia Naomi de Oliveira Uehara, Joao Renato Rebello Pinho, Flair Jose Carrilho, Michele Soares Gomes-Gouvea, Ana Rita Coimbra Motta-Castro
Summary: This study investigates the prevalence and risk factors of Hepatitis B virus infection among Japanese immigrants and their descendants in Sao Paulo. The results show a high rate of susceptibility to HBV infection. Additionally, genotyping of HBV isolates reveals a predominance of genotype HBV/B1.
Article
Medicine, General & Internal
Xue-Di Cheng, Hua-Feng Xu, Feng Wei, Li-Xin Jiang, Hai-Zhou Zhou
Summary: This study revealed a higher recombination rate (23%) among HCV patients in Heilongjiang Province, China, with the unique finding of the 2a/1b recombinant in the 5'UTR, E1, and NS5B regions.
Article
Gastroenterology & Hepatology
Erkin Musabaev, Chris Estes, Shakhlo Sadirova, Shokhista Bakieva, Krestina Brigida, Rick Dunn, Shyamasundaran Kottilil, Poonam Mathur, Ameer Abutaleb, Kathryn Razavi-Shearer, Tim Anstiss, Bakhodir Yusupaliev, Homie Razavi
Summary: Chronic infection with HBV and HCV is a major cause of liver disease and mortality in Uzbekistan. This study demonstrated the feasibility of large-scale simplified testing and treatment to implement a national viral hepatitis elimination program.
LIVER INTERNATIONAL
(2023)
Article
Immunology
Yuanyuan Jia, Xiu Zou, Wei Yue, Jin Liu, Ming Yue, Yang Liu, Li Liu, Peng Huang, Yue Feng, Xueshan Xia
Summary: The prevalence of HCV subtypes 3a and 3b is rapidly increasing in Yunnan, China, with a high level of infection attributed to increased drug use. This highlights the importance of implementing more stringent preventative and therapeutic measures to curb the spread of the virus.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Gastroenterology & Hepatology
Kazumasa Sakamoto, Kiyoaki Ito, Hiroshi Yotsuyanagi, Hiroshi Yatsuhashi, Yasuhito Tanaka, Shuhei Hige, Yasuhiro Takikawa, Yoshiyuki Ueno, Kazuhide Yamamoto, Fumio Imazeki, Jun Inoue, Masayuki Kurosaki, Takeji Umemura, Hidenori Toyoda, Eiji Mita, Kojiro Michitaka, Tatsuji Maeshiro, Norie Yamada, Atsushi Suetsugu, Miwa Kawanaka, Yuya Seko, Kentaro Matsuura, Akinori Okumura, Yoshitaka Fukuzawa, Masaya Sugiyama, Masashi Mizokami, Masashi Yoneda
Summary: This study found that the distribution of HBV genotypes among CHB patients in Japan has changed over time, with an increase in genotype A among young adults and a shift of genotypes B and C towards older age groups. This data provides important baseline information for comparative studies on the impact of universal HBV vaccination.
JOURNAL OF GASTROENTEROLOGY
(2022)
Review
Public, Environmental & Occupational Health
E. Bunthen, Pichetra Ou, Serge Ouoba, Md Razeen Ashraf Hussain, Ko Ko, Shintaro Nagashima, Aya Sugiyama, Tomoyuki Akita, Junko Tanaka
Summary: This study determined the prevalence and genotype distribution of HBV infection in Cambodia through a systematic review with meta-analysis. The results showed a decrease in HBV infection prevalence in Cambodia, indicating the effectiveness of national hepatitis B immunization, improved clinical hygiene, and the use of disposable devices. However, the estimated HBV prevalence among the general population still remains at an intermediate endemicity level, highlighting the need for population screening, high vaccination coverage, health promotion, and HBV surveillance to meet the WHO 2030 goal.
ARCHIVES OF PUBLIC HEALTH
(2022)
Article
Microbiology
Ghobad Moradi, Seyed Moayed Alavian, Fatemeh Gholami, Rashid Ramezani, Leila Ahangarzadeh, Yousef Moradi, Heidar Sharafi
Summary: This study in Iranian prisons revealed high prevalence of hepatitis B and C infections, with risk factors such as history of imprisonment, drug use, unprotected sexual contact, and tattooing contributing to transmission. Special attention to prisons, continuing HBV vaccination, and implementing screening and treatment protocols for HCV-infected individuals can help achieve the goal of eliminating hepatitis by 2030.
Article
Veterinary Sciences
Kuihao Liu, Yiran Zhao, Jun Zhao, Ningwei Geng, Fanliang Meng, Siqi Wang, Jing Li, Zhaobing Zhong, Liya Zhu, Sidang Liu, Ning Li
Summary: This study revealed the molecular epidemiological characteristics of avian HEV in Shandong Province, China, showing genetic diversity and potential novel genotypes. The results also uncovered complex mixed infections of avian HEV in clinical samples, contributing to the enrichment of epidemiological data on avian HEV in the region.
BMC VETERINARY RESEARCH
(2022)
Article
Gastroenterology & Hepatology
Carla Osiowy, Ken Swidinsky, Sarah Haylock-Jacobs, Matthew D. Sadler, Scott Fung, David Wong, Gerald Y. Minuk, Karen E. Doucette, Philip Wong, Edward Tam, Curtis Cooper, Alnoor Ramji, Mang Ma, Carmine Nudo, Keith Tsoi, Carla S. Coffin
Summary: Approximately 5% of the Canadian HBV referral population is seropositive for HDV. HDV infection is closely associated with risk behaviors and both domestic and foreign-born patients with CHB. Those infected with HDV are more likely to suffer from severe liver diseases, including liver cancer, compared to HBV mono-infected patients.
Review
Microbiology
Zeyu Zhao, Meijie Chu, Yichao Guo, Shiting Yang, Guzainuer Abudurusuli, Roger Frutos, Tianmu Chen
Summary: Hepatitis C poses a significant burden in China and requires strategic surveillance, management, and treatment programs. The disease has a varied geographical distribution with certain regions and populations experiencing a higher disease burden. It is crucial to improve diagnosis rates in high-risk populations and asymptomatic individuals, identify secondary infections, especially in those co-infected with HIV, and enhance access to direct antiviral agents (DAAs) to improve cure rates.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Oncology
Shih-Han Hung, Tzong-Hann Yang, Yen-Fu Cheng, Chin-Shyan Chen, Herng-Ching Lin
Summary: This case-control study investigates the associations between head and neck cancer (HNC), hepatitis B virus (HBV), and hepatitis C virus (HCV) infection, and suggests a potential association between HBV and HCV infections and the risk of HNC.
Review
Microbiology
Mohammad Enamul Hoque Kayesh, Michinori Kohara, Kyoko Tsukiyama-Kohara
Summary: Hepatotropic viruses can cause acute and chronic liver infections, leading to morbidity and mortality in humans. In Bangladesh, hepatitis A virus (HAV) and hepatitis E virus (HEV) are the main causative agents of acute hepatitis. This review provides an overview of the epidemiology of these hepatotropic viruses in Bangladesh and discusses their transmission modes and control and prevention measures.
Article
Medicine, General & Internal
Rongkuan Li, Ying Xie, Wenzhi Liu, Yu Ma
Summary: This study aimed to investigate the distribution of HCV genotypes among patients with hepatitis C from 4 ethnic minorities in Liaoning Province, China. The most prevalent genotype among the ethnic minorities was GT1b, followed by GT2a and GT3a, with variations in genotype distribution across different ethnic groups.
Article
Infectious Diseases
Ling-Xiao Qu, Yang Shi, Kai-Yun Chen, Yi-Han Lu, Hong Ren
Summary: This study in Shanghai analyzed the time-spatial clustering patterns of HCV-infected cases and genotype distribution to inform elimination strategies. The results showed a higher mean age of chronic HCV patients compared to acute HCV patients, along with an increase in genotype 3 infections over the years. The findings suggest the need for targeted strategies for high-risk populations related to genotype 3 infection.
BMC INFECTIOUS DISEASES
(2021)
Review
Microbiology
Rayana Maryse Toye, Carmen Luisa Loureiro, Rossana Celeste Jaspe, Fabien Zoulim, Flor Helene Pujol, Isabelle Chemin
Summary: HBV genotypes E to J are understudied and have specific distributions across different regions. Genotype F is the most divergent and has further subgenotypes. There is a lack of data from sub-Saharan Africa and Latin America due to under-representation in clinical and research cohorts.