期刊
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
卷 25, 期 6, 页码 1029-1041出版社
WILEY
DOI: 10.1111/j.1440-1746.2010.06318.x
关键词
critical clicker frequency; health-related quality of life; hepatic encephalopathy; lactulose; minimal hepatic encephalopathy; psychometric hepatic encephalopathy score; psychometry
Hepatic encephalopathy (HE) is a major complication that develops in some form and at some stage in a majority of patients with liver cirrhosis. Overt HE occurs in approximately 30-45% of cirrhotic patients. Minimal HE (MHE), the mildest form of HE, is characterized by subtle motor and cognitive deficits and impairs health-related quality of life. The Indian National Association for Study of the Liver (INASL) set up a Working Party on MHE in 2008 with a mandate to develop consensus guidelines on various aspects of MHE relevant to clinical practice. Questions related to the definition of MHE, its prevalence, diagnosis, clinical characteristics, pathogenesis, natural history and treatment were addressed by the members of the Working Party.
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