Article
Gastroenterology & Hepatology
Emily W. Lopes, Benjamin Lebwohl, Kristin E. Burke, Kerry L. Ivey, Ashwin N. Ananthakrishnan, Paul Lochhead, James M. Richter, Jonas F. Ludvigsson, Walter C. Willett, Andrew T. Chan, Hamed Khalili
Summary: Dietary gluten intake was found to have no association with the risk of Crohn's disease (CD) or ulcerative colitis (UC) in a study of 208,280 US participants. These findings provide reassurance amidst increasing concerns about gluten consumption as a trigger for chronic gastrointestinal diseases.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Food Science & Technology
Xiaoxue Zhu, Xin-Huai Zhao, Qiang Zhang, Na Zhang, Olugbenga P. Soladoye, Rotimi E. Aluko, Yuhao Zhang, Yu Fu
Summary: This article reviews the latest research progress on the relationship between celiac disease (CD) and gluten. It emphasizes the structure and function of gluten peptides related to CD, gluten detection methods, the effects of processing on gluten, and gluten-free diets. The limitations in current CD research are also discussed. This study facilitates a comprehensive understanding of CD and gluten, providing a theoretical reference for future research.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Nutrition & Dietetics
Veronica Segura, Angela Ruiz-Carnicer, Carolina Sousa, Maria de Lourdes Moreno
Summary: The only current treatment for celiac disease is a strict gluten-free diet, but there is a need for non-dietary alternatives to prevent damage from dietary transgressions. Recent therapies for CD focus on degrading gluten, regulating the immune response, and inducing immunological tolerance, with promising results seen in some phase III and II clinical trials.
Article
Gastroenterology & Hepatology
Christopher Ma, Siddharth Singh, Vipul Jairath, Gabriela Radulescu, Stephanie K. M. Ho, May Y. Choi
Summary: Food insecurity is prevalent among patients with celiac disease (CeD), negatively impacting the adoption of a gluten-free diet (GFD) and nutritional intake. Food insecure CeD patients tend to be younger, less educated, nonwhite, living in poverty, and less likely to adhere to a GFD.
JOURNAL OF CLINICAL GASTROENTEROLOGY
(2022)
Article
Nutrition & Dietetics
Amy Posterick, Candace L. Ayars
Summary: Poor adherence to a gluten-free diet can lead to complications for those with celiac disease. This study found that individuals with celiac disease living in urban areas had better dietary adherence than those in nonurban areas. Geographic location, age, years since diagnosis, and income were significant factors in predicting adherence to a gluten-free diet.
Article
Nutrition & Dietetics
Malgorzata Kostecka, Joanna Kostecka-Jarecka, Katarzyna Ilowiecka, Julianna Kostecka
Summary: Celiac disease (CD) is associated with gluten intolerance and affects the nutritional status of patients. This study found that CD patients are at risk of sarcopenic obesity and underweight. Patients with gastrointestinal symptoms are more likely to adhere to a gluten-free diet, and parents and individuals at risk of malnutrition are also more likely to follow dietary guidelines.
Article
Food Science & Technology
Ricardo Dias, Catarina Bessa Pereira, Rosa Perez-Gregorio, Nuno Mateus, Victor Freitas
Summary: Recent studies have shown the potential health benefits of polyphenols in preventing age-related chronic diseases, but more research is needed to understand their role in treating Celiac Disease. Polyphenols have been found to interact with immunogenic peptides, counteract oxidative stress and inflammation, regulate intestinal barrier integrity, affect the gut microbiome, and modulate immune responses, suggesting their potential as nutritional strategy in managing and preventing Celiac Disease.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Review
Nutrition & Dietetics
Bara Aljada, Ahmed Zohni, Wael El-Matary
Summary: The gluten-free diet is popular for treating immune-mediated disorders caused by gluten, but it has disadvantages like high costs, nutritional deficiencies, and social and psychological barriers. Close follow-up with patients following the diet is recommended, and more data is needed to assess its effectiveness in managing mental and cognitive disorders.
Review
Nutrition & Dietetics
Abdulbaqi Al-Toma, Amin Herman, Willem F. Lems, Chris J. J. Mulder
Summary: Impaired bone mineral density is a common complication of adult-onset celiac disease. It is mainly caused by malabsorption of nutrients, changes in bone metabolism associated with inflammation, and decreased overall physical health and mobility. However, research on the surveillance, prevention, and treatment of bone disease in celiac disease is limited. A proper diet and sufficient intake of calcium and vitamin D are essential for reducing fracture risk in adult patients. Individualized approaches should be taken for patients with low bone mineral density or fragility fractures.
Article
Nutrition & Dietetics
Paula Mendive Dubourdieu, Marcela Guerendiain
Summary: Children with autism spectrum disorder (ASD) have different dietary intake and nutritional status compared to typically developing children. They consume more vegetable drinks and gluten-free cereals, but less fish. Their sensory profile score is lower, and children with sensory differences consume less dairy but more cereals and protein foods.
Review
Gastroenterology & Hepatology
Benjamin Lebwohl, Alberto Rubio-Tapia
Summary: The incidence of celiac disease is increasing due to both improved recognition and a real increase of the disorder. The reasons for this true rise are unclear, but may be related to environmental factors. Early-life gluten exposure is a major focus of prevention efforts.
Review
Nutrition & Dietetics
Fardowsa Abdi, Saania Zuberi, Jedid-Jah Blom, David Armstrong, Maria Ines Pinto-Sanchez
Summary: A gluten-free diet is essential for treating celiac disease and may improve symptoms in non-celiac gluten/wheat sensitivity. However, adopting a gluten-free diet or a gluten-restricted diet may increase the risk of malnutrition and nutrient deficiencies. Therefore, patients with these conditions should undergo nutritional assessment and monitoring, and receive multidisciplinary care for long-term nutrition management.
Review
Nutrition & Dietetics
Zsofia Vereczkei, Nelli Farkas, Peter Hegyi, Marcell Imrei, Maria Foldi, Zsolt Szakacs, Szabolcs Kiss, Margit Solymar, Rita Nagy, Judit Bajor
Summary: After a ≥ 1-year gluten-free diet, fat mass of celiac disease patients significantly increased compared to baseline, while fat mass and fat-free mass of these patients were significantly lower compared to non-celiac controls. This indicates that body composition parameters of celiac disease patients continue to differ from non-celiac controls even after long-term adherence to a gluten-free diet.
Review
Food Science & Technology
Amin Abbasi, Sara Bazzaz, Salam A. Ibrahim, Azita Hekmatdoost, Hedayat Hosseini, Sahar Sabahi, Elham Sheykhsaran, Yalda Rahbar Saadat, Mahdi Asghari Ozma, Masoud Lahouty
Summary: As one of the most common autoimmune diseases, celiac disease (CD) affects 1% of the global population and is associated with HLA-DQ2/DQ8 polymorphism and gut microbiota dysbiosis. Diagnosing CD may be challenging due to variations in symptom severity between pediatric and adult populations and their heterogeneity. However, there are currently accessible diagnostic techniques and the only effective treatment is a strict gluten-free diet. Further research is needed to explore dietary and non-dietary-based therapies for managing CD.
FOOD REVIEWS INTERNATIONAL
(2023)
Review
Immunology
Renata Auricchio, Riccardo Troncone
Summary: Celiac disease is an autoimmune disorder triggered by gluten, with prevention strategies focusing on identifying at-risk individuals and eliminating risk factors. Research has shown that both genetic and environmental factors play a role in the development of the disease, suggesting that future interventions could involve protection from infections, manipulation of microbiota, and modulation of T cells.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Agriculture, Multidisciplinary
Leontina Lipan, Bogdan Rusu, Elemer L. Simon, Esther Sendra, Francisca Hernandez, Dan C. Vodnar, Mireia Corell, Angel Carbonell-Barrachina
Summary: The study found that almond milk powder produced from hydroSOStainable almonds had higher levels of TPC, PUFAs, and favorable sensory attributes compared to those from fully irrigated almonds. Moderate and sustained deficit irrigation led to powders with higher content of PUFAs, which are crucial for health. These findings suggest that using water-saving strategies in almond production can lead to high-quality, sustainable products in the food industry.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Food Science & Technology
Paola Sanchez-Bravo, Edgar Chambers, Luis Noguera-Artiaga, Esther Sendra, Edgar Chambers, Angel A. Carbonell-Barrachina
Summary: Consumers generally believe that sustainable products are environmentally friendly, healthier, and of better quality, but over 30% of consumers in the US and Spain are not willing to pay more for sustainable products. Consumers tend to associate sustainable production with just organic farming and higher quality.
FOOD QUALITY AND PREFERENCE
(2021)
Article
Food Science & Technology
Jesus Clemente-Villalba, Marina Cano-Lamadrid, Hanan Issa-Issa, Pablo Hurtado, Francisca Hernandez, Angel A. Carbonell-Barrachina, David Lopez-Lluch
Summary: The study found that there was no significant difference in volatile compounds between protected and non-protected tigernut milks, but there were differences in consumer preference. Additionally, few people were familiar with the PDO Chufa de Valencia, highlighting the need for increased awareness and promotion.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Agronomy
Julio Perez-Marin, Hanan Issa-Issa, Jesus Clemente-Villalba, Jose Miguel Garcia-Garvi, Francisca Hernandez, Angel A. Carbonell-Barrachina, Angel Calin-Sanchez, Luis Noguera-Artiaga
Summary: Through the study and comparison of 8 cherry tomato cultivars, it was found that there were significant differences in morphology, physicochemical parameters, volatile composition, and sensory quality among different cultivars. Seychelles and C-95 were recommended as the best alternatives for replacing Angelle and Katalina in pear and round cherry cultivars, respectively.
Article
Agronomy
Pablo Melgarejo, Pilar Legua, Rafael Martinez-Font, Juan Jose Martinez-Nicolas, Joaquin Sanchez Soriano, Angel A. Carbonell-Barrachina, Francisca Hernandez
Summary: The study showed that using protective nets for cultivating early apricot 'Mikado' is a profitable alternative for farmers, as it does not affect fruit production or quality.
Article
Agronomy
Leontina Lipan, Aaron A. Carbonell-Pedro, Belen Carceles Rodriguez, Victor Hugo Duran-Zuazo, Dionisio Franco Tarifa, Ivan Francisco Garcia-Tejero, Baltasar Galvez Ruiz, Simon Cuadros Tavira, Raquel Muelas, Esther Sendra, Angel A. Carbonell-Barrachina, Francisca Hernandez
Summary: The study assessed the effect of a sustained deficit irrigation strategy on mango yield and quality, revealing that SDI reduced mango size but increased functionality without severely affecting yield.
Review
Nutrition & Dietetics
Hala K. Elmajnoun, MoezAlIslam E. Faris, Suma Uday, Shaun Gorman, James E. Greening, Parvez I. Haris, Abu-Bakr Abu-Median
Summary: It is still uncertain whether children and young adults with type 2 diabetes are at risk of severe COVID-19 infection. Current studies suggest that the incidence of COVID-19 among children with type 2 diabetes is not significantly different from children without diabetes, and implementing programs like intermittent fasting may be effective in preventing complications in these patients. Further research is needed to identify the impact of COVID-19 on this group and the efficacy of intermittent fasting, including Ramadan fasting, among children and young adults with type 2 diabetes.
FRONTIERS IN NUTRITION
(2021)
Article
Environmental Sciences
Miguel Garcia-Villarino, Antonio J. Signes-Pastor, Margaret R. Karagas, Isolina Riano-Galan, Cristina Rodriguez-Dehli, Joan O. Grimalt, Eva Junque, Ana Fernandez-Somoano, Adonina Tardon
Summary: This study found that exposure to metal mixtures impacts growth indicators in children, with negative associations between cadmium and arm circumference, head circumference, and standing height, as well as lead and cobalt with reduced standing height and head circumference, and a positive association between molybdenum and head circumference.
ENVIRONMENTAL RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Antonio J. Signes-Pastor, Megan E. Romano, Brian Jackson, Joseph M. Braun, Kimberly Yolton, Aimin Chen, Bruce Lanphear, Margaret R. Karagas
Summary: Exposure to arsenic during pregnancy may increase the risk of intellectual deficits in children, especially at low exposure levels. This study found a negative association between prenatal maternal urinary arsenic concentrations and childhood cognitive abilities, with stronger effects observed in children whose mothers had lower iAs methylation capacity and lower urinary arsenobetaine concentrations.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2022)
Article
Water Resources
Antonio J. Signes-Pastor, Vicki Sayarath, Brian Jackson, Kathryn L. Cottingham, Tracy Punshon, Margaret R. Karagas
Summary: This study evaluated the exposure to essential and non-essential elements in infants during their first year of life and found that some elements had higher concentrations at 1 year compared to 6 weeks. It also discovered an association between rice consumption and urinary concentrations of certain elements. Further efforts are needed to minimize exposure to non-essential elements while retaining essential elements to protect and promote children's health.
EXPOSURE AND HEALTH
(2023)
Article
Environmental Sciences
Miguel Garcia-Villarino, Antonio J. Signes-Pastor, Isolina Riano-Galan, Ana Cristina Rodriguez-Dehli, Esther Vizcaino, Joan O. Grimalt, Ana Fernandez-Somano, Adonina Tardon
Summary: This study investigated the association between prenatal exposure to POP mixtures and anogenital distance. The results showed a negative correlation between maternal exposure to POPs and AGD in male children, and a positive correlation in female children.
ENVIRONMENTAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Katarzyna Kordas, Alejandra Cantoral, Gauri Desai, Olivia Halabicky, Antonio J. Signes-Pastor, Martha M. Tellez-Rojo, Karen E. Peterson, Margaret R. Karagas
Summary: Concerns have been raised about the contamination of commercially available infant foods worldwide by toxic elements, such as arsenic, cadmium, lead, and mercury. Young children are more vulnerable to the effects of these toxic elements due to higher absorption levels and potentially poorer detoxification capacities. Well-designed epidemiological studies are needed to estimate the exposure of young children to dietary toxicants and determine whether there are causal links between toxicants in children's diets and health outcomes.
JOURNAL OF NUTRITION
(2022)
Article
Multidisciplinary Sciences
Antonio J. Signes-Pastor, Susana Diaz-Coto, Pablo Martinez-Camblor, Manus Carey, Raquel Soler-Blasco, Miguel Garcia-Villarino, Ana Fernandez-Somoano, Jordi Julvez, Paula Carrasco, Aitana Lertxundi, Loreto Santa Marina, Maribel Casas, Andrew A. Meharg, Margaret R. Karagas, Jesus Vioque-Lopez
Summary: This study examined the association between inorganic arsenic exposure and respiratory health in children. It found that even at low exposure levels, inorganic arsenic may be linked to an increased number of respiratory symptoms in childhood.
Article
Nutrition & Dietetics
Alejandro Oncina-Canovas, Sandra Gonzalez-Palacios, Leyre Notario-Barandiaran, Laura Torres-Collado, Antonio Signes-Pastor, Enrique De-Madaria, Miguel Santibanez, Manuela Garcia-de la Hera, Jesus Vioque
Summary: This study aimed to assess the association between three pro-vegetarian food patterns and the risk of esophageal, stomach, and pancreatic cancers. The results showed that adherence to general and healthful pro-vegetarian food patterns was associated with a lower risk of these cancers, while adherence to an unhealthful pro-vegetarian food pattern was associated with a higher risk of stomach cancer.
Article
Environmental Sciences
L. Notario-Barandiaran, A. Irizar, M. Begona-Zubero, R. Soler-Blasco, G. Riutort-Mayol, A. Fernandez-Somoano, A. Tardon, M. Casas, M. Vrijheid, A. Meharg, M. Carey, C. Meharg, K. Ralphs, C. McCreanor, J. O. Grimalt, J. Vioque, A. J. Signes-Pastor
Summary: In this study, the association between adherence to the Mediterranean diet (MD) and urinary metal concentrations in children was evaluated. It was found that high adherence to MD was associated with increased urinary levels of arsenic and copper, but also an increase in non-toxic arsenobetaine concentrations.
ENVIRONMENTAL RESEARCH
(2023)
