Article
Medicine, General & Internal
Yan Shen, Jiajia Wang, Xingtao Zhou, Zhiqiang Yu, Jiaxu Hong, Qihua Le
Summary: This study aimed to investigate the impact of dry eye disease (DED) on uncorrected distance visual acuity (UDVA) and refractive status after small incision lenticule extraction (SMILE). The results showed that compared to the non-DED group, subjects in the DED group had better improvements in UDVA after SMILE. Age, contact lens daily wearing time, and tear meniscus height before surgery were identified as key factors in predicting UDVA after SMILE in contact lens wearers.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Infectious Diseases
Jin Li, Sheng-Wei Ren, Li-Juan Dai, Bo Zhang, Yu-Wei Gu, Chen-Jiu Pang, Yan Wang
Summary: This study describes the development of bacterial keratitis after small incision lenticule extraction in five patients and explores appropriate therapies. The patients were treated with topical antibiotics or surgical interventions, resulting in satisfactory outcomes.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Multidisciplinary Sciences
Jing Zhang, Yuehua Zhou
Summary: The combination of SMILE surgery with allogeneic intrastromal lenticule inlay is effective in treating high hyperopia with astigmatism, showing good safety, efficacy, and reproducibility.
Article
Ophthalmology
N. V. Arulmozhi Varman, Aadithreya Varman, Dinesh Balakumar
Summary: This study evaluated the visual outcomes of patients who underwent SMILE surgery for myopic astigmatism and found that the procedure successfully improved patients' vision.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Kevin K. Maand, Edward E. Manche
Summary: LASIK resulted in greater corneal denervation compared to SMILE in the early postoperative period, though this difference was no longer apparent after 12 months. Despite this, there was no difference in self-reported dry eye symptoms between the 2 groups. Patient-reported dry eye symptoms improved after both LASIK and SMILE procedures.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Multidisciplinary Sciences
Byunghoon Chung, Ik Hee Ryu, In Sik Lee, Jin Kuk Kim, Tae-im Kim, Eung Kweon Kim, Kyoung Yul Seo, Ikhyun Jun
Summary: This study analyzed the clinical outcomes of immediate reapplication of SMILE without adjusting the surgical parameters after suction loss and compared the outcomes with uneventful SMILE. The results showed that immediate reapplication of SMILE without adjusting the surgical parameters after suction loss resulted in surgical outcomes comparable to uneventful SMILE.
SCIENTIFIC REPORTS
(2022)
Article
Ophthalmology
Ahmed Samir, Ayman Lotfy, Mohamed Amin Heikal, Ayman M. Abdelrahman Elsayed
Summary: This study evaluated the effects of SMILE on treating unilateral myopic anisometropia in children with spectacles or contact lens intolerance. The results showed significant improvement in visual acuity postoperatively, with favorable refractive outcomes and low intraoperative complications, indicating the safety and efficacy of SMILE in this patient population.
JOURNAL OF REFRACTIVE SURGERY
(2021)
Article
Medicine, General & Internal
Erika Eskina, Olga Klokova, Roman Damashauskas, Karine Davtyan, Bojan Pajic, Marina Movsesian
Summary: This study aimed to evaluate the impact of thin corneas on the efficacy and safety of small-incision lenticule extraction (SMILE). The results showed that thin corneas had lower uncorrected distance visual acuity at one month after surgery compared to the control group, but the rates were comparable at three months. SMILE was equally safe in patients with thin corneas and the predictability of the procedure was similar between groups. Cap thickness and volume of removed tissue had an impact on the postoperative outcomes in patients with thin corneas.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Lu Zhu, Yan Ji, Xin Yang, Xiaorong Lu, Qiong Wu, Qing Wang, Jiuyi Xia, Meng Li, Ke Hu, Wenjuan Wan
Summary: This research aimed to study the corneal morphological changes in adult patients with myopic anisometropia after small incision lenticule extraction (SMILE) and the safety, efficacy, and predictability of clinical outcomes. The study found that SMILE is predictable, effective, and safe in correcting myopic anisometropia, but it can lead to changes in higher-order aberrations.
FRONTIERS IN MEDICINE
(2022)
Article
Ophthalmology
Bryce Chiang, Gabriel S. Valerio, Edward E. Manche
Summary: The study compared the visual outcomes of WFG-LASIK and SMILE in treating myopic patients. The results showed that at 12 months, WFG-LASIK eyes had faster visual recovery, better low-contrast visual acuity, and greater gains in uncorrected visual acuity compared to SMILE eyes.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Medicine, General & Internal
Estera Igras, Barbara Czarnota-Nowakowska, Ronan O'Caoimh
Summary: This study examined the effectiveness of Small Incision Lenticule Extraction (SMILE) for correcting myopic astigmatism. Results showed that SMILE reliably corrected spherical equivalent (SE) regardless of the type of astigmatism, and significant improvements were observed at 2 months.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Ophthalmology
Dan Z. Reinstein, Timothy J. Archer, Ryan S. Vida, Glenn I. Carp, Julia Reinstein, Theo McChesney, Joseph G. Potter
Summary: This study reports the outcomes of using SMILE for high myopia. The results show that SMILE is effective, safe, stable, and predictable, and it can significantly improve patient satisfaction in the 3 to 12 month follow-up.
JOURNAL OF REFRACTIVE SURGERY
(2022)
Article
Ophthalmology
Dengxin Gao, Xiaotong Lv, Fengju Zhang, Yanzheng Song, Yushan Xu
Summary: 3% Diquafosol sodium eye drop is effective in treating dry eye after FS-LASIK and SMILE in high-myopic eyes. Perioperative anti-dry eye management is crucial, especially for eyes with risk factors such as unstable tear film, high myopia, and FS-LASIK surgery.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2023)
Article
Ophthalmology
Amr A. Gab-Alla
Summary: The study evaluated the use of TPRK with smart pulse technology for correcting myopic residual refractive errors post-SMILE, showing that the technique is safe, predictable, stable, and effective.
Article
Multidisciplinary Sciences
Nikolaus Luft, Jakob Siedlecki, Franziska Reinking, Wolfgang J. Mayer, Benedikt Schworm, Stefan Kassumeh, Siegfried G. Priglinger, Martin Dirisamer
Summary: This study aimed to investigate the influence of extreme corneal keratometry on the outcomes of SMILE surgery. The results showed that SMILE can achieve satisfactory outcomes in patients with steep (>=47D) or flat (<42D) preoperative keratometry, but may induce more spherical aberration in the flat cornea group postoperatively.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Soufiane Souissi, Christophe Baudouin, Antoine Labbe, Pascale Hamard
Summary: The standardized micropulse transscleral diode laser cyclophotocoagulation procedure can lead to a mild decrease in intraocular pressure with a low rate of complications, thereby achieving a relatively good risk-benefit profile, especially for moderately hypertensive refractory glaucoma patients.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Chloe Chamard, Max Villain, Alain Bron, Alexandre Causse, Yacine Bentaleb, Francois Pelen, Christophe Baudouin, Vincent Daien
OPHTHALMIC RESEARCH
(2020)
Review
Cell Biology
Stephane Melik Parsadaniantz, Annabelle Reaux-le Goazigo, Anais Sapienza, Christophe Habas, Christophe Baudouin
Article
Ophthalmology
Sihem Lazreg, Marc Labetoulle, Didier Renault, Christophe Baudouin
Summary: The study demonstrated that combined corneal scrubbing and matrix regenerating therapy can lead to rapid healing and successful resolution of persisting corneal ulcers, including large and deep corneal ulcers.
EUROPEAN JOURNAL OF OPHTHALMOLOGY
(2021)
Editorial Material
Medicine, Legal
Noemie Bonneau, Christophe Baudouin, Francoise Brignole-Baudouin
Summary: The OECD is urging the scientific community to develop and validate alternative methods to reduce the need for animal testing, and proposes combining models and tests into integrated approaches to testing to obtain robust data.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2021)
Article
Environmental Sciences
Mathilde Grosselin, Leila Bouazzi, Thomas Ferreira de Moura, Carl Arndt, Maxime Thorigny, Stephane Sanchez, Alexandre Denoyer
Summary: This study suggests that farmers may have a higher risk of developing severe primary open-angle glaucoma (POAG), potentially due to pesticide exposure. Although more patients in the farmer group underwent filtering surgery, this difference was not statistically significant after adjustment. Further extended studies are needed to confirm the direct link between agricultural profession and the disease.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
Juliette Buffault, Francoise Brignole-Baudouin, Elodie Reboussin, Karima Kessal, Antoine Labbe, Stephane Melik Parsadaniantz, Christophe Baudouin
Summary: Comparing the effects of latanoprost and a Rho-kinase inhibitor on TGF-beta 2-induced glaucoma-like model revealed that the ROCKi was able to reverse the TGF-beta 2-induced cytoskeletal and ECM rearrangements, while latanoprost only affected the extracellular matrix.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Xin Zhang, Stephane Melik-Parsadaniantz, Christophe Baudouin, Annabelle Reaux-Le Goazigo, Nathan Moreau
Summary: The cornea, a crucial part of the eye, requires constant renewal and efficient healing to maintain ocular homeostasis. The Hedgehog signaling pathway plays a vital role in corneal wound healing, promoting cell proliferation, migration, and maintenance of the corneal epithelial barrier.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Immunology
Elodie Reboussin, Juliette Buffault, Francoise Brignole-Baudouin, Annabelle Reaux-Le Goazigo, Luisa Riancho, Celine Olmiere, Jose-Alain Sahel, Stephane Melik Parsadaniantz, Christophe Baudouin
Summary: This study demonstrated the neuroprotective and immunomodulatory effects of MSCs on RGCs in an ex vivo neuroretina explant model. However, co-culture with MSCs led to explant edema and the formation of an epiretinal membrane-like phenotype. The use of MSC secretome may offer the beneficial effects of MSCs without their potential adverse effects through paracrine signaling.
JOURNAL OF NEUROINFLAMMATION
(2022)
Review
Ophthalmology
Marc Labetoulle, Andrea Leonardi, Pierre-Jean Pisella, Christophe Baudouin
Summary: Dry eye disease is a chronic inflammatory disease of the ocular surface that requires long-term therapy. Treatment with ciclosporin A 0.1% cationic emulsion can improve clinical signs and symptoms as early as 4 weeks after treatment initiation.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Letter
Ophthalmology
E. Razlog, J. Gire, C. Arndt, A. Denoyer, S. Lassalle, S. Baillif, A. Martel
JOURNAL FRANCAIS D OPHTALMOLOGIE
(2023)
Article
Ophthalmology
Hanielle Vaitinadapoule, Sylvain Poinard, Zhiguo He, Alina Pascale-Hamri, Justin Thomas, Philippe Gain, Jean-Yves Thuret, Frederic Mascarelli, Gilles Thuret
Summary: This study investigated the interest of using chromatic confocal microscopy (CCM) to characterize guttae in Fuchs endothelial corneal dystrophy (FECD). The results showed that CCM can be an innovative approach to describe and quantify different morphologies of guttae, which could be useful for analyzing different stages of FECD and defining subgroups of patients.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Review
Ophthalmology
Juliette Buffault, Francoise Brignole-Baudouin, Antoine Labbe, Christophe Baudouin
Summary: The purpose of this article is to provide an overview of the existing alternative models for studying the trabecular meshwork (TM). The TM is a complex tissue that regulates aqueous humor outflow and dysfunction of the TM is a major contributor to open-angle glaucoma. Traditional animal models have limitations, leading to a focus on developing alternative in vitro models. These models have shown promise in reducing reliance on animal experimentation in glaucoma research.
CURRENT EYE RESEARCH
(2023)
Article
Ophthalmology
Jason Bacharach, Iqbal Ike K. Ahmed, Elizabeth Sharpe, Michael S. Korenfeld, Steven Zhang, Christophe Baudouin
Summary: This study evaluated the safety and efficacy of a preservative-free formulation of latanoprost (T2345) compared to benzalkonium chloride-preserved latanoprost in patients with primary open-angle glaucoma or ocular hypertension. The results showed that both formulations effectively controlled intraocular pressure, with T2345 demonstrating better safety profile.
CLINICAL OPHTHALMOLOGY
(2023)
Article
Sport Sciences
Morten Carstens Moe, Emin Ozmert, Christophe Baudouin, Abhinav Binadra, Sven Crafoord, Young Jo, Hayyam Kiratli, Melita Moore, Yannis P. Pitsiladis, Udo Rolle, Ben Tan, Ozge Yanik, Richard Budgett, Ugur Erdener, Kathrin Steffen, Lars Engbretsen
Summary: Vision plays a crucial role in athletes' success, with 80% of perceptual input being visual. Eye health and sports medicine are closely intertwined, as the physical nature of sports makes athletes more prone to eye injuries. In addition to injuries, vision problems such as blurred vision and light sensitivity can also affect athletes' performance. Collaboration between sports medicine professionals and ophthalmologists is necessary to provide athletes with appropriate eye care and guidance on eye protection.
BMJ OPEN SPORT & EXERCISE MEDICINE
(2023)