Article
Microbiology
Su-Hyeon Kim, Gashaw Assefa Yehuala, Won Yeong Bang, Jungwoo Yang, Young Hoon Jung, Mi-Kyung Park
Summary: The present study evaluated the safety of Bacillus subtilis (BS) IDCC1101, a newly isolated strain from Cheonggukjang in Korea. Genome sequencing revealed the presence of secondary metabolites, but antibiotic resistance and virulence genes were not transferable. BS IDCC1101 showed susceptibility to most antibiotics, utilized a wide range of carbohydrates, and exhibited various enzyme activities. It did not produce lactate or show hemolytic activity. Furthermore, no toxicity was observed in HaCaT cells and rats. These findings suggest that BS IDCC1101 can be safely used for industrial applications.
Article
Microbiology
Laura M. Brutscher, Claudia Borgmeier, Sean M. Garvey, Jessica L. Spears
Summary: In this study, the safety of Bacillus subtilis BS50 was assessed through preclinical analyses. The results showed that BS50 genome does not encode any known toxins, is susceptible to commonly prescribed antibiotics, and does not have any negative effects on the viability and permeability of human intestinal epithelial cells. Therefore, BS50 has a preclinical safety profile similar to commercial probiotic strains and poses little risk to human health.
Article
Nutrition & Dietetics
Jessica L. Spears, Richard Kramer, Andrey Nikiforov, Marisa O. Rihner, Elizabeth A. Lambert
Summary: The safety and tolerability of the unique strain Bacillus subtilis MB40 was assessed through in silico, in vitro, and in vivo studies. The study confirmed the absence of undesirable genetic elements encoding toxins and antibiotic resistance, and found that MB40 was well tolerated in both rats and healthy human volunteers. Based on the research, it was concluded that Bacillus subtilis MB40 does not pose any human health concerns under the tested conditions.
Article
Veterinary Sciences
Aoyun Li, Meng Wang, Yu Zhang, Zhengrong Lin, Mengen Xu, Lei Wang, Muhammad Fakhar-e-Alam Kulyar, Jiakui Li
Summary: This study investigated the genome and genetic properties of Bacillus subtilis derived from yaks, contributing to understanding the potential prebiotic mechanism of probiotics from a genetic perspective.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Fisheries
Sukanta K. Nayak
Summary: Microorganisms, particularly probiotics like Bacillus species, play a vital role in reducing the use of antibiotics and drugs in aquaculture. They improve growth, nutrition, immunity, and disease resistance in aquatic species, making them a valuable tool for sustainable and safe aquaculture practices.
REVIEWS IN AQUACULTURE
(2021)
Article
Microbiology
Ida Szmigiel, Damian Konkol, Mariusz Korczynski, Marcin Lukaszewicz, Anna Krasowska
Summary: This study found that the addition of 3% fermented rapeseed meal led to beneficial histological changes in the ceca of broiler chickens, inhibited the growth of pathogens, and stimulated the growth of probiotic bacteria.
Article
Microbiology
Xuan Zhang, Yanjun Tong, Xiaomei Lyu, Jing Wang, Yuxue Wang, Ruijin Yang
Summary: The therapeutic effect of B. subtilis-fermented milk on DSS-induced IBD in mice was evaluated in this study. Results showed a decrease in disease activity index, attenuation of intestinal mucosa injury, reduction of inflammatory response, induction of intestinal stem cell proliferation, and promotion of mucosal barrier reconstruction after oral administration of B. subtilis. Additionally, B. subtilis could rebalance the gut microbiota, increasing the abundance of beneficial bacteria while decreasing harmful bacteria.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Food Science & Technology
Hyeon-Ji Lim, Ha-Rim Kim, Su-Ji Jeong, Hee-Jong Yang, Myeong Seon Ryu, Do-Youn Jeong, Seon-Young Kim, Chan-Hun Jung
Summary: Inflammatory bowel disease (IBD) is a chronic inflammatory disease with increasing incidence due to changes in dietary structure. Recent evidence suggests that gut dysbiosis is closely associated with the pathogenesis of IBD. Cheonggukjang, a traditional Korean fermented soybean paste, contains probiotics that may affect the gut microbiota composition and potentially protect against IBD. This study found that traditional and commercial Cheonggukjang samples contain various types of beneficial probiotics. Cheonggukjang reduced the progression of DSS-induced colitis symptoms and improved intestinal barrier integrity. It also suppressed the expression of proinflammatory cytokines and inflammatory mediators through the inactivation of NF-kappa B and MAPK signaling pathways. These findings suggest that Cheonggukjang has protective effects against DSS-induced colitis and may be used as a functional food for improving inflammatory diseases.
Article
Biotechnology & Applied Microbiology
Satish Kumar Rajasekharan, Tali Paz-Aviram, Shmuel Galili, Zipi Berkovich, Ram Reifen, Moshe Shemesh
Summary: The study demonstrates that Bacillus subtilis forms a beneficial biofilm on chickpea milk fibres, producing pulcherrimin pigment, which enhances survivability and resilience to environmental stress through the Spo0A/SinI pathway. This biofilm formation is seen as an adaptation response for strategic survival.
MICROBIAL BIOTECHNOLOGY
(2021)
Article
Immunology
Weiwei Zhao, Xu Wang, Chen Zhao, Zhimin Yan
Summary: The study revealed that B. subtilis R0179 could modulate the immune response by regulating cytokine levels and signaling pathways, showing similar effects during Candida albicans infection.
MICROBIAL PATHOGENESIS
(2021)
Article
Multidisciplinary Sciences
Umair Shabbir, Akanksha Tyagi, Hun Ju Ham, Deog-Hwan Oh
Summary: The germination of black soybeans leads to significant changes in bioactive compounds, resulting in improved antioxidant and anti-inflammatory activities in sprouts compared to seeds. The increase in GABA content and the presence of other beneficial compounds show promising potential in preventing Alzheimer's disease.
Article
Medicine, Research & Experimental
Agnes Jakab, Fruzsina Kovacs, Noemi Balla, Zoltan Toth, Agota Ragyak, Zsofi Sajtos, Kinga Csillag, Csaba Nagy-Koteles, Daniel Nemes, Ildiko Bacskay, Istvan Pocsi, Laszlo Majoros, Akos T. Kovacs, Renato Kovacs
Summary: This study demonstrates that surfactin, a secondary metabolite derived from Bacillus subtilis, exhibits antifungal properties against Candida albicans. It inhibits the growth, adhesion, and morphogenesis of C. albicans, increases the level of reduced glutathione, and enhances the efficacy of fluconazole. Surfactin also affects the gene transcription of C. albicans, with down-regulation of genes involved in morphogenesis and metabolism, and up-regulation of genes associated with ribosome biogenesis, iron metabolism, and drug transport.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Veterinary Sciences
Karin Allenspach, Chi-Hsuan Sung, Jose Joaquin Ceron, Camila Peres Rubio, Agnes Bourgois-Mochel, Jan S. Suchodolski, Lingnan Yuan, Debosmita Kundu, Joan Colom Comas, Kieran Rea, Jonathan P. Mochel
Summary: This study investigated the effects of DE-CA9 (TM) on healthy Beagle dogs and found that it can reduce oxidative stress markers and have positive effects on protein and lipid metabolism in serum and feces.
VETERINARY SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Romain Villeger, Emilie Pinault, Karine Vuillier-Devillers, Karine Grenier, Cornelia Landolt, David Ropartz, Vincent Sol, Maria C. Urdaci, Philippe Bressollier, Tan-Sothea Ouk
Summary: This study found that using isomaltooligosaccharides (IMOSs) can improve the fitness and benefits of probiotic Bacillus subtilis CU1. IMOSs can modify the metabolism and functions of the strain, enhance the germination of Bacillus subtilis CU1, and increase the concentration of the strain.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Applied
Chen Hsu, Hsin-Ya Tsai, Chi-Fon Chang, Chien-Chih Yang, Nan-Wei Su
Summary: Flavonoid O-phosphorylation provides a potent modification to enhance the oral bioavailability of flavonoids. The enzyme BsFPS, discovered in this study, efficiently catalyzes the phosphorylation of structurally-diverse flavonoids. The findings highlight the potential for developing biosynthetic platforms to obtain new phosphorylated flavonoids for pharmaceutical and nutraceutical applications.
Article
Chemistry, Applied
Ziba Hosseinpour, Vida Rezaei
Summary: Sol-gel chemistry is a unique method for constructing high-performance flexible sensors. This study successfully developed a novel naked eye sensor for fast detection of oxalate by incorporating indole inside the pores of sol-gel silica glasses. The sol-gel films exhibited excellent sensitivity, leaching resistance, and response time under optimized conditions. The prepared sensor showed a wide detection range and low detection limit for oxalate, and displayed good precision for both inter-day and intra-day measurements.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
S. T. Sarhir, R. Belkhou, A. Bouseta, A. A. Hayaloglu
Summary: In order to optimize the quality of Lben, this study investigated the impact of starter, fermentation conditions and substrate composition on its organoleptic and technological characteristics using response surface methodology. An optimized model for Lben production was developed based on fermentation time, Lben sensory quality and its biological activities.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Kornelia Kadac-Czapska, Malgorzata Rutkowska, Eliza Knez, Piotr Konieczka, Malgorzata Grembecka
Summary: The quality of food is crucial for the healthy growth of children, and this study investigated the levels of mercury in infant formulas. The analysis revealed significant variations in mercury levels among different products. While the current assessment suggests mercury content is within acceptable limits, elevated levels in certain products may pose health risks.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Velisaria-Eleni Gerogianni, Eirini A. Panagopoulou, Paraskevi B. Vasilakopoulou, Vaios T. Karathanos, Antonia Chiou
Summary: This study evaluated the content of free and bound polar phenols in Corinthian currant and identified phenolic acids and flavonoids as components of its bound polar phenol fraction. An efficient method for the release of bound phenols from the fruit matrix was also applied. This research has significant implications for understanding the health benefits of Corinthian currant.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Jose Eduardo de Matos Paz, Aline Macedo Dantas, David Douglas de Sousa Fernandes, Marcio Jose Coelho Pontes
Summary: This work presents a new methodology based on digital images and multivariate analysis for the classification of sugar samples based on their color. By analyzing the frequency distribution of color indices and developing classification models, high accuracy can be achieved. The proposed method offers advantages such as low cost, simplicity, and non-destructiveness.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Maria Guerrero-Chanivet, Manuel J. Valcarcel-Munoz, M. Valme Garcia-Moreno, M. Carmen Rodriguez-Dodero, Dominico A. Guillen-Sanchez
Summary: This study conducted a comprehensive analysis of Brandies de Jerez aged in Sherry Casks with different seasoning times and types, demonstrating significant differences in chemical composition and sensory characteristics among the brandies.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Chayuttapong Malai, Kanvisit Maraphum, Khwantri Saengprachatanarug, Seree Wongpichet, Arthit Phuphaphud, Jetsada Posom
Summary: The quality of cassava can be measured using NIR spectroscopy to determine the starch content and dry matter content. A model developed from different scanning methods and surface conditions was compared, and the accuracy of the model using selected wavelengths was assessed. The prediction accuracy was found to depend on the scanning method, with the horizontal spectra obtaining the highest accuracy. The CARS-PLSR method was considered appropriate for predicting starch content, and the BOSS-PLSR method for predicting dry matter content.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Abhishek Sharma, Atul Kumar
Summary: This study detected antibiotics residues in goat milk in the Western Himalayan region of India and assessed the related health risks. It was found that the contamination did not pose acute health risks to adults and children at current levels, but children may be at a greater risk. The study highlights the need for monitoring and education to protect human health.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Livya Alves Oliveira, Stephanie Michelin Santana Pereira, Kelly Aparecida Dias, Stefany da Silva Paes, Mariana Grancieri, Luis Gonzalo Salinas Jimenez, Carlos Wanderlei Piler de Carvalho, Eugenio Eduardo de Oliveira, Hercia Stampini Duarte Martino, Ceres Mattos Della Lucia
Summary: This study characterized the powders of Tenebrio molitor and Gryllus assimilis, two types of insects, at different developmental stages. The powders were found to be rich in proteins, minerals, and vitamins, and showed good digestibility and solubility. The developmental stage of the insects affected their nutritional composition and functional properties.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Fernanda Rodrigues Spinelli, Jucara Aparecida Andre, Paulo Gustavo Celso, Marlos Schuck Vicenzi, Eder Julio Kinast, Caren Regina Cavichioli Lamb, Glauco Bertoldo
Summary: The production, marketing and consumption of grape juices have been constantly increasing in recent years due to consumers' search for products with proven health benefits. Brazilian data shows that grape juice produced from V. labrusca L. and hybrids has a lower soluble solids content, with more than half of the production falling between 14 and 16 degrees Brix. This suggests the need to re-discuss the 16 degrees Brix limit established by CXS 247-2005.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Fatima Zohra Issaad, Ala Abdessemed, Khalid Bouhedjar, Hani Bouyahmed, Mouna Derdour, Karima Ouffroukh, Ahmed Fellak, Mohamed Abd Salem Dems, Salah Chihoub, Radouane Bechlem, Abdelkader Mahrouk, Mourad Houasnia, Amine Belaidi, Khaled Moumed, Zohir Sebai, Faiza Saidani, Houria Akmouche
Summary: This study investigates the differences in physicochemical parameters and composition of monovarietal extra virgin olive oil from different varieties in Algeria, and applies machine learning techniques for classification and verification analysis.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Seyedeh Faezeh Taghizadeh, Ramin Rezaee, Gholamreza Karimi
Summary: This study assessed the risk of simultaneous oral exposure to a combination of 20 pesticides and 7 metals in citrus fruit samples. The results showed that the oral exposure to non-carcinogenic metals did not pose a major risk, while nickel intake presented a moderate risk. The intake of organophosphorus compounds indicated a moderate risk, while no significant risk was found for pyrethroids.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Jian Zhao, Min Guo, Patricia Martins, Joao Ramos, Lingxi Li, Baoshan Sun
Summary: This study analyzed the structural composition of eight-year-old Syrah red wines produced using different winemaking technologies. The results showed that the structural features of polymeric polyphenols, including the proportions of proanthocyanidins, amino acids, phenolic acids, and anthocyanins, as well as the mean degree of polymerization, varied significantly depending on the winemaking technology used. These findings are important for winemakers to control the polymeric polyphenol composition of wines.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Mahunan Francois Assogba, Roger Houechene Ahouansou, N. Olive Ruth Djohi, Yenoukounme Euloge Kpoclou, Gildas Dona Anihouvi, Herbert Ogouyo Iko Af Afe, Biowa Franck Tchibozo, Caroline Douny, Jacques Mahillon, Marie -Louise Scippo, Djidjoho Joseph Hounhouigan, Victor Bienvenu Anihouvi
Summary: This study assessed the performance of new equipment and aimed to reduce the level of polycyclic aromatic hydrocarbons (PAHs) in the end products. The results showed that using QUALISANI equipment with charcoal achieved the highest thermal efficiency and the lowest PAH levels in compliance with standards.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)
Article
Chemistry, Applied
Mehmet Ali Saridas, Erdal Agcam, Nafiye Unal, Asiye Akyildiz, Sevgi Paydas Kargi
Summary: Turkey's geographical location and climate conditions are suitable for growing various fruit species, with apricots being the most famous. Local and foreign varieties differ significantly in terms of soluble solids and acid content. The low taste values in foreign varieties are mainly due to their genotypic structure and early harvest. There are also differences in the main sugars and acid content among different apricot varieties.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2024)