期刊
JOURNAL OF FLUID MECHANICS
卷 734, 期 -, 页码 -出版社
CAMBRIDGE UNIV PRESS
DOI: 10.1017/jfm.2013.474
关键词
biological fluid dynamics; flow-vessel interactions; microfluidics
资金
- US NSF [CMMI-0970071]
- Div Of Civil, Mechanical, & Manufact Inn
- Directorate For Engineering [0970071] Funding Source: National Science Foundation
Direct and non-invasive measurement of the pressure distribution in test sections of a micro-channel is a challenging, if not an impossible, task. Here, we present an analytical method for extracting the pressure distribution in a deformable microchannel under flow. Our method is based on a measurement of the channel deflection profile as a function of applied hydrostatic pressure; this initial measurement generates 'constitutive curves' for the deformable channel. The deflection profile under flow is then matched to the constitutive curves, providing the hydrodynamic pressure distribution. The method is validated by measurements on planar microfluidic channels against analytic and numerical models. The accuracy here is independent of the nature of the wall deformations and is not degraded even in the limit of large deflections, zeta(max)/2h(0) = O(1), with zeta(max) and 2h(0) being the maximum deflection and the unperturbed height of the channel, respectively. We discuss possible applications of the method in characterizing micro-flows, including those in biological systems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据