Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection

Detrimental Contribution of the Immuno-Inhibitor B7-H1 to Rabies Virus Encephalitis

(2014) M. Lafon et al.   JOURNAL OF IMMUNOLOGY

NFATc1 Regulates PD-1 Expression upon T Cell Activation

(2014) K. J. Oestreich et al.   JOURNAL OF IMMUNOLOGY

Epigenetic Modifications Induced by Blimp-1 Regulate CD8+ T Cell Memory Progression during Acute Virus Infection

(2013) Hyun Mu Shin et al.   IMMUNITY

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

(2012) Suzanne L Topalian et al.   CURRENT OPINION IN IMMUNOLOGY

ZBTB32 Is an Early Repressor of the CIITA and MHC Class II Gene Expression during B Cell Differentiation to Plasma Cells

(2012) H. S. Yoon et al.   JOURNAL OF IMMUNOLOGY

Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

(2012) Julie R. Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiple Histone Methyl and Acetyltransferase Complex Components Bind the HLA-DRA Gene

(2012) Nancy M. Choi et al.   PLoS One

Chronic Virus Infection Enforces Demethylation of the Locus that Encodes PD-1 in Antigen-Specific CD8+ T Cells

(2011) Ben Youngblood et al.   IMMUNITY

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

(2011) Erika Cretney et al.   NATURE IMMUNOLOGY

Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection

(2011) Charlly Kao et al.   NATURE IMMUNOLOGY

Role of PD-1 in regulating acute infections

(2010) Keturah E Brown et al.   CURRENT OPINION IN IMMUNOLOGY

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

(2010) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation

(2010) Koichi Araki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+T cell dysfunction in melanoma patients

(2010) Julien Fourcade et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PU.1 Binds to a Distal Regulatory Element That Is Necessary for B Cell-Specific Expression of CIITA

(2010) H. Yoon et al.   JOURNAL OF IMMUNOLOGY

Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

(2009) Rachel L. Rutishauser et al.   IMMUNITY

Blimp-1 Transcription Factor Is Required for the Differentiation of Effector CD8+ T Cells and Memory Responses

(2009) Axel Kallies et al.   IMMUNITY

A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection

(2009) Haina Shin et al.   IMMUNITY

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

(2009) R. J. Johnston et al.   SCIENCE

Blimp-1 directly repressesIl2and theIl2activatorFos, attenuating T cell proliferation and survival

(2008) Gislâine A. Martins et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The PD-1/PD-L costimulatory pathway critically affects host resistance to the pathogenic fungus Histoplasma capsulatum

(2008) E. Lazar-Molnar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients

(2007) Guoping Peng et al.   MOLECULAR IMMUNOLOGY