2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+T cell responses

IFN-  Dictates Allograft Fate via Opposing Effects on the Graft and on Recipient CD8 T Cell Responses

(2014) S. M. Coley et al.   JOURNAL OF IMMUNOLOGY

A Critical Precursor Frequency of Donor-Reactive CD4+ T Cell Help Is Required for CD8+ T Cell-Mediated CD28/CD154-Independent Rejection

(2014) M. L. Ford et al.   JOURNAL OF IMMUNOLOGY

PD-1-Dependent Mechanisms Maintain Peripheral Tolerance of Donor-Reactive CD8+ T Cells to Transplanted Tissue

(2014) B. H. Koehn et al.   JOURNAL OF IMMUNOLOGY

AP-1 is involved in ICOS gene expression downstream of TCR/CD28 and cytokine receptor signaling

(2012) Masashi Watanabe et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Selective CD28 Blockade Attenuates Acute and Chronic Rejection of Murine Cardiac Allografts in a CTLA-4-Dependent Manner

(2011) T. Zhang et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Three-Year Outcomes from BENEFIT, a Randomized, Active-Controlled, Parallel-Group Study in Adult Kidney Transplant Recipients

(2011) F. Vincenti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Solid Organ Allograft Survival Improvement in the United States: The Long-Term Does Not Mirror the Dramatic Short-Term Success

(2011) S. A. Lodhi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Tight Regulation of Memory CD8+ T Cells Limits Their Effectiveness during Sustained High Viral Load

(2011) Erin E. West et al.   IMMUNITY

Cutting Edge: An NK Cell-Independent Role for Slamf4 in Controlling Humoral Autoimmunity

(2011) D. R. Brown et al.   JOURNAL OF IMMUNOLOGY

A Phase III Study of Belatacept Versus Cyclosporine in Kidney Transplants from Extended Criteria Donors (BENEFIT-EXT Study)

(2010) A. Durrbach et al.   AMERICAN JOURNAL OF TRANSPLANTATION

A Phase III Study of Belatacept-based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

(2010) F. Vincenti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Long-Term Renal Allograft Survival in the United States: A Critical Reappraisal

(2010) K. E. Lamb et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Altered expression of signalling lymphocyte activation molecule (SLAM) family receptors CS1 (CD319) and 2B4 (CD244) in patients with systemic lupus erythematosus

(2010) J. R. Kim et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function

(2010) Bijan Raziorrouh et al.   HEPATOLOGY

Absence of mouse 2B4 promotes NK cell–mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis

(2010) Stephen N. Waggoner et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: The Adapters EAT-2A and -2B Are Positive Regulators of CD244- and CD84-Dependent NK Cell Functions in the C57BL/6 Mouse

(2010) N. Wang et al.   JOURNAL OF IMMUNOLOGY

Five-Year Safety and Efficacy of Belatacept in Renal Transplantation

(2010) F. Vincenti et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inducing CTLA-4-Dependent Immune Regulation by Selective CD28 Blockade Promotes Regulatory T Cells in Organ Transplantation

(2010) N. Poirier et al.   Science Translational Medicine

Belatacept-Based Regimens Versus a Cyclosporine A-Based Regimen in Kidney Transplant Recipients: 2-Year Results From the BENEFIT and BENEFIT-EXT Studies

(2010) Christian P. Larsen et al.   TRANSPLANTATION

Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation

(2010) Bertram Bengsch et al.   PLoS Pathogens

The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses

(2009) Alison Crawford et al.   CURRENT OPINION IN IMMUNOLOGY

Effector Functions of Donor-Reactive CD8 Memory T Cells Are Dependent on ICOS Induced During Division in Cardiac Grafts

(2008) A. D. Schenk et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Toward experimental assessment of receptor occupancy: TGN1412 revisited

(2008) Zoe Waibler et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY

Signaling Signatures and Functional Properties of Anti-Human CD28 Superagonistic Antibodies

(2008) Zoe Waibler et al.   PLoS One