RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

Stable RAGE-Heparan Sulfate Complexes Are Essential for Signal Transduction

(2013) Ding Xu et al.   ACS Chemical Biology

Opposing Roles of Membrane and Soluble Forms of the Receptor for Advanced Glycation End Products in Primary Respiratory Syncytial Virus Infection

(2012) Allison L. Miller et al.   JOURNAL OF INFECTIOUS DISEASES

Solution Structure of the Soluble Receptor for Advanced Glycation End Products (sRAGE)

(2011) Zsuzsa Sárkány et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase

(2011) Sarah E. Ewald et al.   JOURNAL OF EXPERIMENTAL MEDICINE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

HMGB1 and RAGE in Inflammation and Cancer

(2010) Gary P. Sims et al.   Annual Review of Immunology

Homodimerization Is Essential for the Receptor for Advanced Glycation End Products (RAGE)-mediated Signal Transduction

(2010) Hongliang Zong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 1.5 Å Crystal Structure of Human Receptor for Advanced Glycation Endproducts (RAGE) Ectodomains Reveals Unique Features Determining Ligand Binding

(2010) HaJeung Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Receptor for Advanced Glycation End Products (RAGE) and the Lung

(2010) Stephen T. Buckley et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Carboxylated N-glycans on RAGE promote S100A12 binding and signaling

(2010) Geetha Srikrishna et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons

(2010) Josh Gregorio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Complement C3a, CpG Oligos, and DNA/C3a Complex Stimulate IFN-  Production in a Receptor for Advanced Glycation End Product-Dependent Manner

(2010) B. H. Ruan et al.   JOURNAL OF IMMUNOLOGY

The C-terminal acidic tail is responsible for the inhibitory effects of HMGB1 on efferocytosis

(2010) Sami Banerjee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Chronic Inflammation in Obesity and the Metabolic Syndrome

(2010) Rosário Monteiro et al.   MEDIATORS OF INFLAMMATION

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

(2010) A. L. Blasius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation

(2010) K. Kawane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3

(2010) M. Sasai et al.   SCIENCE

Structural Basis for Ligand Recognition and Activation of RAGE

(2010) Michael Koch et al.   STRUCTURE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Tempering the wrath of RAGE: An emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation

(2009) Shi Fang Yan et al.   ANNALS OF MEDICINE

Alternative splicing of the murine receptor for advanced glycation end-products (RAGE) gene

(2009) Anastasia Z. Kalea et al.   FASEB JOURNAL

Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity

(2009) Y. J. Crow et al.   HUMAN MOLECULAR GENETICS

Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

(2009) Martin Schlee et al.   IMMUNITY

RAGE: therapeutic target and biomarker of the inflammatory response-the evidence mounts

(2009) Ravichandran Ramasamy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

(2009) Hideyuki Yanai et al.   NATURE

Cytoplasmic nucleic acid sensors in antiviral immunity

(2009) Priya Ranjan et al.   TRENDS IN MOLECULAR MEDICINE

The DNA Sugar Backbone 2′ Deoxyribose Determines Toll-like Receptor 9 Activation

(2008) Tobias Haas et al.   IMMUNITY

Interaction of the RAGE Cytoplasmic Domain with Diaphanous-1 Is Required for Ligand-stimulated Cellular Migration through Activation of Rac1 and Cdc42

(2008) Barry I. Hudson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for translation termination on the 70S ribosome

(2008) Martin Laurberg et al.   NATURE

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

(2008) Sarah E. Ewald et al.   NATURE

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

(2008) Boyoun Park et al.   NATURE IMMUNOLOGY

V domain of RAGE interacts with AGEs on prostate carcinoma cells

(2008) Edith Uetz-von Allmen et al.   PROSTATE