Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide–MHC

Naive Precursor Frequencies and MHC Binding Rather Than the Degree of Epitope Diversity Shape CD8+ T Cell Immunodominance

(2014) M. F. Kotturi et al.   JOURNAL OF IMMUNOLOGY

T Cell Activation Results in Conformational Changes in the Src Family Kinase Lck to Induce Its Activation

(2013) A. Stirnweiss et al.   Science Signaling

The molecular determinants of CD8 co-receptor function

(2012) David K. Cole et al.   IMMUNOLOGY

The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy

(2012) Salvatore Valitutti   Frontiers in Immunology

CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I

(2011) Vasily Rybakin et al.   EMBO REPORTS

Opposite Effects of Endogenous Peptide-MHC Class I on T Cell Activity in the Presence and Absence of CD8

(2011) J. D. Stone et al.   JOURNAL OF IMMUNOLOGY

Constitutively Active Lck Kinase in T Cells Drives Antigen Receptor Signal Transduction

(2010) Konstantina Nika et al.   IMMUNITY

Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection

(2010) Jeremy Juang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8 Controls T Cell Cross-Reactivity

(2010) L. Wooldridge et al.   JOURNAL OF IMMUNOLOGY

CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery

(2010) M. N. Artyomov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient stochastic simulation of reaction–diffusion processes via direct compilation

(2009) Mieszko Lis et al.   BIOINFORMATICS

A Single-Chain H-2Db Molecule Presenting an Influenza Virus Nucleoprotein Epitope Shows Enhanced Ability at Stimulating CD8+ T Cell Responses In Vivo

(2009) M. J. Palmowski et al.   JOURNAL OF IMMUNOLOGY

An endogenous peptide positively selects and augments the activation and survival of peripheral CD4+ T cells

(2009) Wan-Lin Lo et al.   NATURE IMMUNOLOGY

The molecular basis of TCR germline bias for MHC is surprisingly simple

(2009) K Christopher Garcia et al.   NATURE IMMUNOLOGY

An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a

(2009) Peter J R Ebert et al.   NATURE IMMUNOLOGY

Quantitative challenges in understanding ligand discrimination by αβ T cells

(2007) Ofer Feinerman et al.   MOLECULAR IMMUNOLOGY