Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand–dependent terminal keratinocyte differentiation

Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis

(2012) Aditya Murthy et al.   IMMUNITY

Inflammatory Skin and Bowel Disease Linked toADAM17Deletion

(2011) Diana C. Blaydon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis

(2011) Slaheddine Marrakchi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities

(2011) Mario E. Lacouture et al.   SUPPORTIVE CARE IN CANCER

Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17

(2011) Thorsten Maretzky et al.   Nature Communications

Flaky Tail Mouse Denotes Human Atopic Dermatitis in the Steady State and by Topical Application with Dermatophagoides pteronyssinus Extract

(2010) Catharina Sagita Moniaga et al.   AMERICAN JOURNAL OF PATHOLOGY

TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation

(2010) Xiping Cheng et al.   CELL

Fibroblast growth factor receptors 1 and 2 in keratinocytes control the epidermal barrier and cutaneous homeostasis

(2010) Jingxuan Yang et al.   JOURNAL OF CELL BIOLOGY

Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice

(2010) Aditya Murthy et al.   JOURNAL OF CLINICAL INVESTIGATION

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

(2010) Athena Chalaris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

(2010) Adan Aguirre et al.   NATURE

Tumor Necrosis Factor-  and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice

(2009) D. Surguladze et al.   CANCER RESEARCH

Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor

(2009) Tang-Cheng Lee et al.   GENESIS

Shedding of Collagen XVII/BP180 in Skin Depends on Both ADAM10 and ADAM9

(2009) Claus-Werner Franzke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epidermal homeostasis: a balancing act of stem cells in the skin

(2009) Cédric Blanpain et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Beyond Wavy Hairs

(2008) Marlon R. Schneider et al.   AMERICAN JOURNAL OF PATHOLOGY

Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions

(2008) Azza Eissa et al.   BIOLOGICAL CHEMISTRY

Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

(2008) Shadmehr Demehri et al.   PLOS BIOLOGY

The Epidermal Growth Factor Receptor System in Skin Repair and Inflammation

(2007) Saveria Pastore et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY