The cell fate determinant Llgl1 influences HSC fitness and prognosis in AML

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML

(2012) Z. Li et al.   BLOOD

Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia

(2012) R. Beekman et al.   BLOOD

CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARγ signaling

(2012) Katrin Faber et al.   JOURNAL OF CLINICAL INVESTIGATION

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

(2011) Nicolas Goardon et al.   CANCER CELL

Cholesterol synthesis-related enzyme oxidosqualene cyclase is required to maintain self-renewal in primary erythroid progenitors

(2011) C. Mejia-Pous et al.   CELL PROLIFERATION

Cooperation between both Wnt/ -catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion

(2011) J. M. Perry et al.   GENES & DEVELOPMENT

Self-renewal related signaling in myeloid leukemia stem cells

(2011) Florian H. Heidel et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF

(2011) C. Tamm et al.   JOURNAL OF CELL SCIENCE

Deregulated apoptosis signaling in core-binding factor leukemia differentiates clinically relevant, molecular marker-independent subgroups

(2011) S C Lück et al.   LEUKEMIA

The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic stem cells

(2011) Chozhavendan Rathinam et al.   NATURE IMMUNOLOGY

Atypical protein kinase C (aPKC  and aPKC ) is dispensable for mammalian hematopoietic stem cell activity and blood formation

(2011) A. Sengupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity

(2010) Kristin J. Hope et al.   Cell Stem Cell

Gene expression profiling in AML with normal karyotype can predict mutations for molecular markers and allows novel insights into perturbed biological pathways

(2010) A Kohlmann et al.   LEUKEMIA

Regulation of myeloid leukaemia by the cell-fate determinant Musashi

(2010) Takahiro Ito et al.   NATURE

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

(2010) Michael G Kharas et al.   NATURE MEDICINE

A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway

(2010) J. Menendez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant Splicing of Hugl-1 Is Associated with Hepatocellular Carcinoma Progression

(2009) X. Lu et al.   CLINICAL CANCER RESEARCH

Balancing dormant and self-renewing hematopoietic stem cells

(2009) Anne Wilson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

HOXA9 is required for survival in human MLL-rearranged acute leukemias

(2008) J. Faber et al.   BLOOD

The Transcription Factor EGR1 Controls Both the Proliferation and Localization of Hematopoietic Stem Cells

(2008) Irene M. Min et al.   Cell Stem Cell