Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia

Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML

(2011) E. M. Payne et al.   BLOOD

Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner

(2011) Min Sup Song et al.   CELL

Endogenous Myc maintains the tumor microenvironment

(2011) N. M. Sodir et al.   GENES & DEVELOPMENT

Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E

(2010) Andrew C. Hsieh et al.   CANCER CELL

CD4+ T Cells Contribute to the Remodeling of the Microenvironment Required for Sustained Tumor Regression upon Oncogene Inactivation

(2010) Kavya Rakhra et al.   CANCER CELL

Myc-Induced MicroRNAs Integrate Myc-Mediated Cell Proliferation and Cell Fate

(2010) Jong Wook Kim et al.   CANCER RESEARCH

The interaction between Myc and Miz1 is required to antagonize TGF -dependent autocrine signaling during lymphoma formation and maintenance

(2010) J. van Riggelen et al.   GENES & DEVELOPMENT

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia

(2010) Konstantinos J. Mavrakis et al.   NATURE CELL BIOLOGY

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

(2009) A. Gutierrez et al.   BLOOD

Genetic dissection of the miR-17 92 cluster of microRNAs in Myc-induced B-cell lymphomas

(2009) P. Mu et al.   GENES & DEVELOPMENT

miR-19 is a key oncogenic component of mir-17-92

(2009) V. Olive et al.   GENES & DEVELOPMENT

PTEN and the PI3-Kinase Pathway in Cancer

(2008) Nader Chalhoub et al.   Annual Review of Pathology-Mechanisms of Disease

A Novel Recurrent Chromosomal Inversion Implicates the Homeobox Gene Dlx5 in T-Cell Lymphomas from Lck-Akt2 Transgenic Mice

(2008) Y. Tan et al.   CANCER RESEARCH

PTEN Deletion and Concomitant c-Myc Activation Do Not Lead to Tumor Formation in Pancreatic β Cells

(2008) Anna Radziszewska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modelling Myc inhibition as a cancer therapy

(2008) Laura Soucek et al.   NATURE

Combined Analysis of Murine and Human Microarrays and ChIP Analysis Reveals Genes Associated with the Ability of MYC To Maintain Tumorigenesis

(2008) Chi-Hwa Wu et al.   PLoS Genetics