Lipid phosphate phosphatase 3 enables efficient thymic egress

Thymic Emigration: When and How T Cells Leave Home

(2014) M. A. Weinreich et al.   JOURNAL OF IMMUNOLOGY

Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development

(2011) Alejandro López-Juárez et al.   GLIA

An alternative method for intrathymic injections in mice

(2010) Robin Blair-Handon et al.   LAB ANIMAL

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

(2010) Sergio E. Alvarez et al.   NATURE

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells

(2010) Guangwei Liu et al.   NATURE IMMUNOLOGY

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

Oral Therapy for Multiple Sclerosis — Sea Change or Incremental Step?

(2010) William M. Carroll   NEW ENGLAND JOURNAL OF MEDICINE

SphK1 Regulates Proinflammatory Responses Associated with Endotoxin and Polymicrobial Sepsis

(2010) P. Puneet et al.   SCIENCE

Neural Crest-Derived Pericytes Promote Egress of Mature Thymocytes at the Corticomedullary Junction

(2010) M. A. Zachariah et al.   SCIENCE

Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice

(2009) Eric Camerer et al.   JOURNAL OF CLINICAL INVESTIGATION

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

(2009) Trung H.M. Pham et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inducible Capillary Formation in Lymphatic Endothelial Cells by Blocking Lipid Phosphate Phosphatase-3 Activity

(2009) Kazutaka Senda et al.   Lymphatic Research and Biology

The receptor S1P1 overrides regulatory T cell–mediated immune suppression through Akt-mTOR

(2009) Guangwei Liu et al.   NATURE IMMUNOLOGY

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE

Sphingosine-1-phosphate regulation of mammalian development

(2008) M KONO   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The vascular S1P gradient—Cellular sources and biological significance

(2008) T HLA   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

Principles of bioactive lipid signalling: lessons from sphingolipids

(2008) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY