The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

(2010) R. Eric Davis et al.   NATURE

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

(2009) J. W. Friedberg et al.   BLOOD

The Lymphoma-associated Fusion Tyrosine Kinase ITK-SYK Requires Pleckstrin Homology Domain-mediated Membrane Localization for Activation and Cellular Transformation

(2009) Sue Rigby et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment of rheumatoid arthritis with a syk kinase inhibitor: A twelve-week, randomized, placebo-controlled trial

(2008) Michael E. Weinblatt et al.   ARTHRITIS AND RHEUMATISM

Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas

(2008) A L Feldman et al.   LEUKEMIA

Chromosomal Abnormalities in Cancer

(2008) Stefan Fröhling et al.   NEW ENGLAND JOURNAL OF MEDICINE