Article
Agricultural Engineering
Sandip K. Singh, Brian K. Saulnier, David B. Hodge
Summary: This study investigated the impact of bmr mutations on lignin properties and plant response to cell wall deconstruction. The results show that bmr sorghum lines have lower abundance of water-extractable sugars and alkali-saponifiable p-coumarate, and higher glucose hydrolysis yields. The lignin in bmr sorghums exhibited higher solubility and lower molar mass after pretreatment. The Atlas bmr line showed significant differences in lignin content, lignin monomer distribution, and inter-unit linkages compared to the control line.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Plant Sciences
Hannah M. Tetreault, Tammy Gries, Sarah Liu, John Toy, Zhanguo Xin, Wilfred Vermerris, John Ralph, Deanna L. Funnell-Harris, Scott E. Sattler
Summary: The Bmr30 gene mutation results in significantly reduced CHI activity, impaired accumulation of total flavonoids and total anthocyanins. In the bmr30 mutants, the level of the flavone lignin monomer tricin was reduced 20-fold in the stem relative to wild type, and to undetectable levels in the leaf tissue of the mutants.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Noemi Gesteiro, Ana Butron, Sara Estevez, Rogelio Santiago
Summary: This research found significant negative correlations between cell wall-bound p-coumaric acid and syringyl monomers with maize resistance to attack by the Mediterranean corn borer. Therefore, it is advisable to use cell wall-bound p-coumaric acid in pest-resistant crop breeding programs.
Article
Plant Sciences
Catalina Duran Garzon, Michelle Lequart, Quentin Charras, Francoise Fournet, Leo Bellenger, Helene Sellier-Richard, Catherine Giauffret, Wilfred Vermerris, Jean-Marc Domon, Catherine Rayon
Summary: Maize is highly sensitive to low temperature, and changes in photosynthetic and cell wall metabolisms were investigated in this study. The study found that the biomass of the plant was reduced, and photosynthesis was altered under chilling conditions. There were also changes observed in the composition of the cell wall. The findings highlight the sensitivity of maize to low temperature and the adaptive responses in photosynthetic and cell wall metabolisms.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Article
Plant Sciences
Francisco Roberto Quiroz-Figueroa, Abraham Cruz-Mendivil, Enrique Ibarra-Laclette, Luz Maria Garcia-Perez, Rosa Luz Gomez-Peraza, Greta Hanako-Rosas, Eliel Ruiz-May, Apolinar Santamaria-Miranda, Rupesh Kumar Singh, Gerardo Campos-Rivero, Elpidio Garcia-Ramirez, Jose Alberto Narvaez-Zapata
Summary: Fusarium verticillioides is a fungal pathogen that causes harm to maize and results in significant agricultural and economic losses. This study compared the response of two different genotypes of maize roots to Fv infection and found that the resistant genotype exhibited slower and less severe infection compared to the susceptible genotype. Transcriptomic and histological analyses revealed differences in the expression of cell wall-related genes and lignified cells, suggesting the importance of the root cell wall in defense against Fv.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Alba Manga-Robles, Rogelio Santiago, Rosa A. Malvar, Victor Moreno-Gonzalez, Silvia Fornale, Ignacio Lopez, Maria Luz Centeno, Jose L. Acebes, Jesus Miguel Alvarez, David Caparros-Ruiz, Antonio Encina, Penelope Garcia-Angulo
Summary: The study found that H lignin subunits influenced the rind penetration strength of maize, while a high ferulic acid content increased lodging resistance and diferulates decreased it. The structural features of the cell wall may play a key role in determining the strength and lodging susceptibility of maize stems.
Article
Agriculture, Multidisciplinary
Kun Li, Xue Yang, Xiao-gang Liu, Xiao-jiao Hu, Yu-jin Wu, Qi Wang, Fei-qian Ma, Shu-qiang Li, Hong-wu Wang, Zhi-fang Liu, Chang-ling Huang
Summary: Cell wall architecture plays a crucial role in stalk strength and forage digestibility. This study utilized genetic mapping techniques to investigate the development of cell wall during secondary cell wall lignification in maize stalks and identified QTLs associated with cell wall components and digestibility traits. The findings indicate that cell wall-related traits are regulated by multiple genes, with stage-specific expression after silking.
JOURNAL OF INTEGRATIVE AGRICULTURE
(2022)
Article
Polymer Science
Sherif Mohamed El-Ganainy, Mohamed A. Mosa, Ahmed Mahmoud Ismail, Ashraf E. Khalil
Summary: Lignin, a waste product of pulp and paper industries, can be used as a carrier for drug delivery in the form of carbon nanoparticles. These lignin-loaded carbon nanoparticles have shown antifungal properties and promote growth in maize plants.
Article
Food Science & Technology
Clerio Valentin Damasceno Junior, Samantha Godoy, Adriana Gonela, Carlos Alberto Scapim, Adriana Grandis, Wanderley D. dos Santos, Claudete Aparecida Mangolin, Marcos S. Buckeridge, Maria de Fatima P. S. Machado
Summary: This study investigates the biochemical composition of the pericarp cell walls of different inbred lines of popcorn and discovers that lignin content and composition are related to popping expansion.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
Article
Agronomy
Daniela Simoes, Eugenio Diogo, Eugenia de Andrade
Summary: Maize is an important staple crop worldwide, but it is highly susceptible to fungal infections, particularly by certain species of Fusarium. These infections can lead to significant reductions in yield and quality, as well as the production of mycotoxins. In Portugal and similar Mediterranean countries, F. verticillioides and F. subglutinans are the most common species infecting maize. However, the incidence of diseases and mycotoxin levels have increased, suggesting the presence of other mycotoxigenic Fusarium species or changes in exogenous conditions. Monitoring Fusarium species occurrence in the field is crucial to address these threats. A recent survey in Portugal identified the presence of F. andiyazi in maize crops for the first time, highlighting the need for further studies to prevent its spread and mitigate its impact on maize production and farmers' livelihoods.
Article
Plant Sciences
Julio S. S. Bernal, Anjel M. M. Helms, Ana A. A. Fontes-Puebla, Thomas J. J. DeWitt, Michael V. V. Kolomiets, John M. M. Grunseich
Summary: Domestication has a greater impact on the abundances and diversity of maize root volatiles than northward spread and modern breeding. The preference of the herbivore for maize roots is correlated with volatile diversity and herbivore resistance. Changes in abundances of individual volatiles are evident at the level of volatile groups, and maize domestication has the greatest effects.
Article
Agronomy
Talita Vigo Longhi, Renata Rodrigues Robaina, Deived Uilian de Carvalho, Admilton Goncalves de Oliveira, Rui Pereira Leite Junior, Maria Isabel Balbi-Pena
Summary: According to the study, ten species of plants belonging to the Poaceae family can serve as alternative hosts for Xvv. Additionally, 23 asymptomatic species were found to have epiphytic colonization by Xvv. Scanning electron microscopy revealed that Xvv bacteria were distributed on the leaf surface and exhibited colonization in the intercellular tissues of some plant species. However, only a low number of bacterial cells were found on the leaf surface of asymptomatic species, and no internal tissue colonization was observed in millet.
Article
Agronomy
Jingwei Yan, Jing Li, Heping Zhang, Ya Liu, Aying Zhang
Summary: This study identified the function of the Zea mays WRKY transcription factor, ZmWRKY104, in salt stress response. ZmWRKY104 increases the salt tolerance of maize by regulating the expression of ZmSOD4.
Article
Plant Sciences
Alden C. Perkins, Jonathan P. Lynch
Summary: The research shows that seminal roots can improve the acquisition of nitrogen and phosphorus in maize seedlings, with increased seed size associated with maize domestication possibly facilitating the increase in seminal root number. The study also suggests that the optimal number of seminal roots for nutrient acquisition in teosinte is constrained by its limited seed carbohydrate reserves.
Article
Plant Sciences
Sina Barghahn, Georgios Saridis, Melissa Mantz, Ute Meyer, Jaqueline C. Mellueh, Johana C. Misas Villamil, Pitter F. Huesgen, Gunther Doehlemann
Summary: This study analyzed the transcriptome, proteome, and N-terminome of Zea mays leaves treated with different substances to explore cell processes related to cell death and plant immunity. The results showed distinct and time-dependent biological processes being activated in response to different substances. The correlation analysis of the transcriptome and proteome identified general and trigger-specific markers for cell death in Zea mays. Additionally, specific regulation of proteases, particularly papain-like cysteine proteases, was observed during regulated cell death.
Article
Immunology
Seong-Ho Choi, Michael Dagher, Felicia Ruffin, Lawrence P. Park, Batu K. Sharma-Kuinkel, Maria Souli, Alison M. Morse, Emily M. Eichenberger, Lauren Hale, Celia Kohler, Bobby Warren, Brenda Hansen, Felix Mba Medie, Lauren M. McIntyre, Vance G. Fowler
Summary: This study identified several risk factors for R-SAB, with the highest risk observed among black hemodialysis patients. Higher levels of RANTES in R-SAB compared to matched controls suggest a need for further investigation.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Genetics & Heredity
Brecca R. Miller, Alison M. Morse, Jacqueline E. Borgert, Zihao Liu, Kelsey Sinclair, Gavin Gamble, Fei Zou, Jeremy R. B. Newman, Luis G. Leon-Novelo, Fabio Marroni, Lauren M. McIntyre
Summary: Researchers can infer differences between non-tester alleles by using testcross design and hypothesis testing methods to compare more alleles with fewer crosses. Utilizing BayesASE allows for effective estimation of allelic effects and formal comparison between conditions of allelic imbalance levels.
G3-GENES GENOMES GENETICS
(2021)
Article
Chemistry, Analytical
Goncalo J. Gouveia, Amanda O. Shaver, Brianna M. Garcia, Alison M. Morse, Erik C. Andersen, Arthur S. Edison, Lauren M. McIntyre
Summary: The study developed stable and sustainable reference materials (RM) using the iterative batch averaging method (IBAT), which was then applied in a metabolomics experiment to estimate the proportion of sample variation.
ANALYTICAL CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Mai Mehanna, Caitrin W. McDonough, Steven M. Smith, Yan Gong, John G. Gums, Arlene B. Chapman, Julie A. Johnson, Lauren McIntyre, Rhonda M. Cooper-DeHoff
Summary: This study identified metabolic signatures associated with baseline PRA and their linkages with the effects of thiazides and beta-blockers in regulating blood pressure, providing insights into the mechanisms underlying BP response.
Article
Cell Biology
Xiaqing Zhao, Forrest T. Golic, Benjamin R. Harrison, Meghna Manoj, Elise Hoffman, Neta Simon, Richard Johnson, Michael J. MacCoss, Lauren M. McIntyre, Daniel E. L. Promislow
Summary: Activity levels and metabolome-wide profiles are strongly associated with age, and many individual metabolites show a strong association with lifespan. The metabolome provides a biological clock that predicts not only sample age but also future mortality rates and lifespan.
Article
Chemistry, Physical
Michael K. Riley, Wilfred Vermerris
Summary: The study investigated the influence of variations in lignin sources on the properties of lignin nanoparticles, and found that LNPs can serve as delivery vehicles for DNA and exhibit potential for gene therapy applications.
Article
Multidisciplinary Sciences
Hugo E. Cuevas, Clara M. Cruet-Burgos, Louis K. Prom, Joseph E. Knoll, Lauren R. Stutts, Wilfred Vermerris
Summary: Anthracnose caused by C. sublineola is a major issue for sorghum production globally. Studying resistance alleles is crucial for safeguarding yield, and this study identified potential genetic regions for anthracnose resistance in sorghum, especially on chromosomes 4, 5, and 8.
SCIENTIFIC REPORTS
(2021)
Article
Biology
Katrina Sherbina, Luis G. Leon-Novelo, Sergey Nuzhdin, Lauren M. McIntyre, Fabio Marroni
Summary: The study suggests that a minimum number of allele-specific reads and replicates are needed to detect allelic imbalance and differences between conditions with a power greater than 80%. Increasing the number of replicates is more effective in increasing power than adding coverage without impacting type I error. The study provides a Python package for simulating AI scenarios and estimating power in detecting AI and differences between conditions.
BMC RESEARCH NOTES
(2021)
Article
Biochemistry & Molecular Biology
Tianyuan Liu, Pedro Salguero, Marko Petek, Carlos Martinez-Mira, Leandro Balzano-Nogueira, Ziva Ramsak, Lauren McIntyre, Kristina Gruden, Sonia Tarazona, Ana Conesa
Summary: PaintOmics is a web server for integrative analysis of multi-omics data, offering various new analysis features and comprehensive pathway knowledge, providing novel insights into regulatory biology.
NUCLEIC ACIDS RESEARCH
(2022)
Article
Multidisciplinary Sciences
Danielle E. Mor, Francisco Huertas, Alison M. Morse, Rachel Kaletsky, Coleen T. Murphy, Vrinda Kalia, Gary W. Miller, Olexander Moskalenko, Ana Conesa, Lauren M. McIntyre
Summary: Parkinson's disease is a neurodegenerative disorder that affects multiple cell types. The mechanisms behind the disease are not fully understood, hindering development of targeted therapies. By utilizing high-throughput molecular profiling technologies and the multi-omics data analysis tool GAIT-GM, researchers have discovered an association between branched-chain amino acid metabolism and cholinergic neurons, as well as cholinergic neurodegeneration in a C. elegans PD model.
SCIENTIFIC REPORTS
(2022)
Article
Genetics & Heredity
Adalena Nanni, Alison M. Morse, Jeremy R. B. Newman, Nicole E. Choquette, Jessica M. Wedow, Zihao Liu, Andrew D. B. Leakey, Ana Conesa, Elizabeth A. Ainsworth, Lauren M. McIntyre
Summary: The study found that different maize genotypes exhibit varying transcriptional responses to sustained elevated ozone concentration, with some genotypes showing a higher number of differentially expressed genes under ozone stress, and one genotype exhibiting a response different from the others. Additionally, genes associated with photosynthesis and reactive oxygen species show a common response across different genotypes.
Article
Chemistry, Analytical
Carter K. Asef, Markace A. Rainey, Brianna M. Garcia, Goncalo J. Gouveia, Amanda O. Shaver, Franklin E. Leach, Alison M. Morse, Arthur S. Edison, Lauren M. McIntyre, Facundo M. Fernandez
Summary: Ion mobility spectrometry (IM) provides valuable data for identifying unknown metabolites in non-targeted metabolomics. This study presents a workflow using de novo molecular formula annotation, MS/MS structure elucidation, and machine learning predictions to identify differential unknown metabolites in Caenorhabditis elegans mutant strains. However, the performance of this approach is limited by instrumentation and data analysis challenges, resulting in a relatively low success rate in filtering candidate structures.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Amanda O. Shaver, Brianna M. Garcia, Goncalo J. Gouveia, Alison M. Morse, Zihao Liu, Carter K. Asef, Ricardo M. Borges, Franklin E. Leach, Erik C. Andersen, I. Jonathan Amster, Facundo M. Fernandez, Arthur S. Edison, Lauren M. McIntyre
Summary: Untargeted metabolomics studies face challenges in identifying the same feature across studies. In this research, an anchored experimental design was developed, integrating three genetic studies of Caenorhabditis elegans. An anchor strain was included in every sample collection to estimate treatment effects within each batch and combine treatment effects across batches. This approach allows for comparison of stable spectral features across time without the need for compound identification.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Jacob A. Lewis, Bixia Zhang, Rishi Harza, Nathan Palmer, Gautam Sarath, Scott E. Sattler, Paul Twigg, Wilfred Vermerris, ChulHee Kang
Summary: Flavonoids are potent antioxidants that play a crucial role in plant defense and detoxification. Understanding the structures and catalytic mechanisms of three reductases provides insights into the biosynthesis and metabolic regulation of flavonoids.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Meeting Abstract
Pharmacology & Pharmacy
M. Mehanna, Y. Gong, C. McDonough, J. Gums, A. Chapman, J. Johnson, L. McIntyre, R. Cooper-DeHoff
CLINICAL PHARMACOLOGY & THERAPEUTICS
(2022)