Therapeutic potential of targeting IRES-dependent c-myc translation in multiple myeloma cells during ER stress

MNK1-Induced eIF-4E Phosphorylation in Myeloma Cells: A Pathway Mediating IL-6-Induced Expansion and Expression of Genes Involved in Metabolic and Proteotoxic Responses

(2014) Yijiang Shi et al.   PLoS One

Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762

(2013) A. Chaidos et al.   BLOOD

hnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stress

(2012) Fabrizio Damiano et al.   BIOCHEMICAL JOURNAL

MYC addiction: a potential therapeutic target in MM

(2012) W. M. Kuehl et al.   BLOOD

ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth

(2012) Lori S. Hart et al.   JOURNAL OF CLINICAL INVESTIGATION

The feed-forward loop between YB-1 and MYC is essential for multiple myeloma cell survival

(2012) K S Bommert et al.   LEUKEMIA

Deregulated MYC expression induces dependence upon AMPK-related kinase 5

(2012) Lidan Liu et al.   NATURE

MNK kinases facilitate c-myc IRES activity in rapamycin-treated multiple myeloma cells

(2012) Y Shi et al.   ONCOGENE

A Cell-Based Method for Screening RNA-Protein Interactions: Identification of Constitutive Transport Element-Interacting Proteins

(2012) Robert L. Nakamura et al.   PLoS One

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor

(2010) B. Hoang et al.   BLOOD

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

IL-6-Induced Stimulation of c-Myc Translation in Multiple Myeloma Cells Is Mediated by Myc Internal Ribosome Entry Site Function and the RNA-Binding Protein, hnRNP A1

(2008) Y. Shi et al.   CANCER RESEARCH

Heterogeneous Nuclear Ribonucleoprotein A1 Regulates Cyclin D1 and c-mycInternal Ribosome Entry Site Function through Akt Signaling

(2008) Oak D. Jo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heterogeneous nuclear ribonuclear protein K interacts with the enterovirus 71 5' untranslated region and participates in virus replication

(2008) J.-Y. Lin et al.   JOURNAL OF GENERAL VIROLOGY