H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK

Silencing of the DNA Mismatch Repair Gene MLH1 Induced by Hypoxic Stress in a Pathway Dependent on the Histone Demethylase LSD1

(2014) Yuhong Lu et al.   Cell Reports

Replication Stress and Chromatin Context Link ATM Activation to a Role in DNA Replication

(2013) Monica M. Olcina et al.   MOLECULAR CELL

Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis

(2012) Lin Yuan et al.   EMBO REPORTS

p53-mediated heterochromatin reorganization regulates its cell fate decisions

(2012) Sathish Kumar Mungamuri et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hypoxia-Induced Epigenetic Regulation and Silencing of the BRCA1 Promoter

(2011) Y. Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of ATM/Chk2/p53 Pathway Components Accelerates Tumor Development and Contributes to Radiation Resistance in Gliomas

(2010) Massimo Squatrito et al.   CANCER CELL

ARF-dependent regulation of ATM and p53 associated KZNF (Apak) protein activity in response to oncogenic stress

(2010) Shan Wang et al.   FEBS LETTERS

Discovery and characterization of chromatin states for systematic annotation of the human genome

(2010) Jason Ernst et al.   NATURE BIOTECHNOLOGY

PrognoScan: a new database for meta-analysis of the prognostic value of genes

(2009) Hideaki Mizuno et al.   BMC Medical Genomics

The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

(2009) Alejandra Loyola et al.   EMBO REPORTS

Experimentally Derived Metastasis Gene Expression Profile Predicts Recurrence and Death in Patients With Colon Cancer

(2009) J. Joshua Smith et al.   GASTROENTEROLOGY

KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis

(2009) Chunyan Tian et al.   NATURE CELL BIOLOGY

ATM Activation and Signaling under Hypoxic Conditions

(2008) Z. Bencokova et al.   MOLECULAR AND CELLULAR BIOLOGY