Article
Otorhinolaryngology
Coralie Mignot, Anica Schunke, Charlotte Sinding, Thomas Hummel
Summary: The study did not find a clear peripheral adaptation as measured by EOG, but suggests the possibility of such an effect based on a few subjects showing decreases in EOG amplitude over stimulations.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Immunology
Zhenjie Ma, Weihao Li, Liujing Zhuang, Tieqiao Wen, Ping Wang, Hongmeng Yu, Yongliang Liu, Yiqun Yu
Summary: In this study, TMEM59 is identified as a critical regulator in maintaining and regenerating the olfactory epithelium. TMEM59 deletion leads to transcriptional changes, affecting genes associated with olfactory transduction and inflammatory/immune response. Loss of TMEM59 impairs olfactory functions, decreases proliferation, and promotes infiltration of inflammatory cells. TMEM59 also plays a role in the regeneration of the olfactory epithelium, with reduced proliferative cells and sensory neurons. Anti-inflammatory treatment can recover neuronal generation and olfactory functions, suggesting a potential therapy for olfactory dysfunction associated with inflammation.
BRAIN BEHAVIOR AND IMMUNITY
(2023)
Article
Biology
Tayfun Tumkaya, Safwan Burhanudin, Asghar Khalilnezhad, James Stewart, Hyungwon Choi, Adam Claridge-Chang
Summary: Animals use olfactory receptors to navigate mates, food, and danger. Research on Drosophila reveals that only a small fraction of olfactory sensory neurons can individually drive avoidance or attraction behavior, suggesting that most neurons have neutral effects. Additionally, wind and hunger have minimal impact on these responses. Comparisons between single- and double-ORN responses also contradict simple pooling rules, indicating that complex interactions may be responsible for the observed behavioral effects.
Article
Biology
Kaitlin Ching, Jennifer T. Wang, Tim Stearns, Danelle Devenport
Summary: This study discovered that centrioles migrate together during dendrite outgrowth in olfactory sensory neurons (OSNs) and form cilia during maturation. They are associated with microtubule nucleation factors and the parental centriole forms a cilium before other centrioles.
Article
Neurosciences
Joseph D. Zak
Summary: Olfactory sensory neurons are located in a restricted area of the nasal cavity, making it challenging to access and measure them in living animals. This study presents a new method that overcomes these limitations and allows for long-term observation of olfactory sensory neurons in mice.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Physiology
Hanyu Fu, Jingwei Zhou, Shan Li, Ying Zhang, Zhiyun Chen, Yingying Yang, Anan Li, Dejuan Wang
Summary: General anesthesia impairs olfactory detection in adult mice by increasing neuronal activity in the olfactory bulb. This effect may be mediated by increased excitability of mitral cells and weakened inhibitory input.
Review
Neurosciences
Federica Genovese, Johannes Reisert, Vladimir J. Kefalov
Summary: The past decades have seen significant progress in understanding the function of photoreceptors and olfactory sensory neurons. This progress has been driven by the combination of physiological experimental tools and genetic manipulations, which have allowed researchers to identify molecular players in sensory neuron transduction cascades, explore how properties impact stimulus detection and disease effects on vision and smell.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Lina-Marielle Krysewski, Nicole Power Guerra, Annika Glatzel, Carsten Holzmann, Veronica Antipova, Oliver Schmitt, Libo Yu-Taeger, Huu Phuc Nguyen, Andreas Wree, Martin Witt
Summary: This study investigated olfactory deficits in a transgenic rat model of Huntington's disease (HD). The results suggest that the main olfactory epithelium (MOE) is temporarily affected in HD, while the vomeronasal (VNE) remains relatively stable.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Neurosciences
Du Chen, Hankui Cheng, Siyan Liu, Umar Al-Sheikh, Yuedan Fan, Duo Duan, Wenjuan Zou, Linhui Zhu, Lijun Kang
Summary: The glial L-Type VGCC EGL-19 plays a crucial role in regulating calcium variations and behavioral outputs in C. elegans, and it also affects the morphologies of sensory neurons and glial cells.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2022)
Article
Medicine, Research & Experimental
Wenwen Ren, Zhenjie Ma, Li Wang, Xiaoyu Feng, Hongmeng Yu, Yiqun Yu
Summary: This study elucidates the role of Lgr5(+) cells in the homeostasis and regeneration of the olfactory epithelium, potentially providing a candidate for cell-based therapy against olfactory dysfunction.
Article
Neurosciences
Sinisa Prelic, Merid N. Getahun, Sabine Kaltofen, Bill S. Hansson, Dieter Wicher
Summary: Olfaction is a crucial sensory modality in insects, but the regulation of odorant receptor function and intracellular signaling pathways in the sensory periphery are not fully understood. This study investigates the presence and role of nitric oxide (NO) signaling in the antennal tissue of Drosophila. The researchers find that while the NO signaling machinery is present, inhibiting or activating the NO-cGMP pathway does not affect olfactory responses. Additionally, cyclic nucleotides cAMP and cGMP have no effect on olfactory responses, suggesting that NO may not be a regulator of olfactory transduction in insects.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2023)
Article
Anatomy & Morphology
Bo-Ra Kim, Min-Seok Rha, Hyung-Ju Cho, Joo-Heon Yoon, Chang-Hoon Kim
Summary: This study used olfactory specific genes to investigate the development of the mouse olfactory system from prenatal to postnatal stages. The olfactory epithelium (OE) and olfactory bulb (OB) were found to become multilayered during development, accompanied by the differentiation of olfactory neurons. Interestingly, the development of olfactory cilia and differentiation of OE were found to progress dramatically after birth, suggesting the influence of air exposure.
FRONTIERS IN NEUROANATOMY
(2023)
Review
Biochemistry & Molecular Biology
Gowoon Son, Ali Jahanshahi, Seung-Jun Yoo, Jackson T. Boonstra, David A. Hopkins, Harry W. M. Steinbusch, Cheil Moon
Summary: Neuropathological research on the olfactory system in Alzheimer's disease suggests that olfactory dysfunction may be an early indicator of the disease, related to amyloid-beta production and neuroinflammation.
Review
Cell Biology
Dieter Wicher, Fabio Miazzi
Summary: The majority of insect olfactory receptors belong to two distinct protein families - ionotropic receptors (IRs) related to the ionotropic glutamate receptor family, and odorant receptors (ORs) evolved from the gustatory receptor family. Both types assemble into heteromeric ligand-gated cation channels, addressing environmental and ecological challenges insects face.
CELL AND TISSUE RESEARCH
(2021)
Article
Otorhinolaryngology
Boo-Young Kim, Ju Yeon Park, Jung Ho Bae
Summary: This study aimed to investigate the cytotoxic effects of intermittent hypoxia on the mouse olfactory epithelium and the relationship between hypoxia concentration and olfactory system destruction. The results showed that hypoxia damaged the olfactory neuroepithelium and brain tissue in mice, decreased the activity of olfactory marker genes and neurogenesis. The oxygen concentration may affect changes in the olfactory neuroepithelium. Olfactory ensheathing cells may be a major factor in the recovery of the olfactory neuroepithelium.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
(2023)
Article
Multidisciplinary Sciences
Eloise J. Cave, Stephen M. Kajiura
SCIENTIFIC REPORTS
(2018)
Review
Fisheries
Kyle C. Newton, Andrew B. Gill, Stephen M. Kajiura
JOURNAL OF FISH BIOLOGY
(2019)
Article
Engineering, Environmental
Lela S. Schlenker, Megan J. Welch, Tricia L. Meredith, Edward M. Mager, Ebrahim Lari, Elizabeth A. Babcock, Greg G. Pyle, Philip L. Munday, Martin Grosell
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2019)
Article
Marine & Freshwater Biology
Kyle C. Newton, Stephen M. Kajiura
Article
Fisheries
Melanie D. Doan, Stephen M. Kajiura
JOURNAL OF FISH BIOLOGY
(2020)
Article
Plant Sciences
Xing-Hai Zhang, Nicholas Pizzo, Mohamed Abutineh, Xiao-Lu Jin, Sarah Naylon, Tricia L. Meredith, Lyndon West, John M. Harlin
PLANT GROWTH REGULATION
(2020)
Article
Marine & Freshwater Biology
Kyle C. Newton, Stephen M. Kajiura
Article
Zoology
E. J. Cave, S. M. Kajiura
Article
Anatomy & Morphology
Danielle N. Ingle, Tricia L. Meredith, Justin R. Perrault, Jeanette Wyneken
Summary: This study utilizes micro-computed tomography to investigate the craniofacial and axial bifurcation in sea turtles from south Florida beaches. Various types of bifurcation were observed, leading to differences in body dimensions, skull morphology, and vertebral measurements between normal and anomalous specimens. The findings suggest potential implications for the health assessment of sea turtle populations in relation to environmental factors.
JOURNAL OF MORPHOLOGY
(2021)
Article
Fisheries
Kathryn A. Ayres, James T. Ketchum, Rogelio Gonzalez-Armas, Felipe Galvan-Magana, Alex Hearn, Fernando R. Elorriaga-Verplancken, Edgar M. Hoyos-Padilla, Stephen M. Kajiura
Summary: Established in 1995, Cabo Pulmo National Park has seen a significant increase in fish biomass. A study using an unmanned aerial vehicle (UAV) found lemon sharks, bull sharks, and Pacific nurse sharks in shallow coastal habitats, with sharks being more common in the afternoon, potentially using warmer shallow areas for thermoregulation. This highlights the efficacy of UAV surveys for species identification compared to previous terrestrial surveys.
JOURNAL OF FISH BIOLOGY
(2021)
Article
Education, Special
Maria D. Vasquez-Colina, Leila Shatara, Tricia L. Meredith
Summary: This mixed methods research study examined 79 dual-enrolled students in a research methodology course, finding that students perceived increased knowledge in undergraduate research content but slightly decreased usefulness perception. Students felt more comfortable with research, expressed benefits, but also experienced anxiety when setting expectations and making comparisons. The study contributes by blending quantitative and qualitative data to make meta-inferences about the dichotomy of being a dual-enrolled student in research courses, and by introducing the concept of research capital in the context of dual enrollment programs in a specific state.
JOURNAL OF ADVANCED ACADEMICS
(2022)
Article
Fisheries
Stephen M. Kajiura, John C. Loyer, Cassandra Ruddy, Marianne E. Porter
Summary: The Caribbean reef shark Carcharhinus perezi exhibits a unique behavior of resting on the substrate, which is not seen in other members of its genus. A study quantified the swimming kinematics of C. perezi in the wild, showing that its head yaw frequency is higher than its tailbeat frequency, but the amplitude of the tail exceeds that of the head. In comparison to its ram ventilating congener C. limbatus, C. perezi shows lower velocity, head yaw frequency, and tailbeat frequency.
JOURNAL OF FISH BIOLOGY
(2022)
Article
Ecology
Mary E. Bowers, Stephen M. Kajiura
Summary: Global climate change affects oceanic characteristics and animal distribution. Inconsistencies in the migratory movement of blacktip sharks off the U.S. East Coast challenge current knowledge. Published data can be interpreted in multiple ways and perpetuate uncertain observations, calling for further research on the movement ecology of blacktip sharks in this region.
ENVIRONMENTAL BIOLOGY OF FISHES
(2023)
Review
Remote Sensing
Paul A. Butcher, Andrew P. Colefax, Robert A. Gorkin, Stephen M. Kajiura, Naima A. Lopez, Johann Mourier, Cormac R. Purcell, Gregory B. Skomal, James P. Tucker, Andrew J. Walsh, Jane E. Williamson, Vincent Raoult
Summary: This paper discusses the application of drones in wildlife management and research over the past decade, particularly focusing on their value and importance in shark research. Drones have helped to fill knowledge gaps about shark behavior and their significance in ecosystems, while also contributing to reducing dangerous encounters between sharks and humans. Additionally, the paper explores the future trends in drone technology for shark monitoring and research.
Article
Behavioral Sciences
Kyle C. Newton, Stephen M. Kajiura