KPNA2 promotes metabolic reprogramming in glioblastomas by regulation of c-myc

Hypoxia-Sensitive COMMD1 Integrates Signaling and Cellular Metabolism in Human Macrophages and Suppresses Osteoclastogenesis

(2017) Koichi Murata et al.   IMMUNITY

Karyopherin α-2 is a reliable marker for identification of patients with high-risk stage II colorectal cancer

(2017) Dongjun Jeong et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Therapeutic strategies of drug repositioning targeting autophagy to induce cancer cell death: from pathophysiology to treatment

(2017) Go J. Yoshida   Journal of Hematology & Oncology

Metabolic heterogeneity and plasticity of glioma stem cells in a mouse glioblastoma model

(2017) Shunsuke Shibao et al.   NEURO-ONCOLOGY

Silencing of karyopherin α2 inhibits cell growth and survival in human hepatocellular carcinoma

(2017) Yunfeng Yang et al.   Oncotarget

E2F1, a Novel Regulator of Metabolism

(2017) Pierre-Damien Denechaud et al.   Frontiers in Endocrinology

Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity

(2017) Daniel V. Brown et al.   PLoS One

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Cancer statistics in China, 2015

(2016) Wanqing Chen et al.   CA-A CANCER JOURNAL FOR CLINICIANS

KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis

(2016) Ling-Yu Wang et al.   Cell Reports

MIR517Cinhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation

(2015) Yuntao Lu et al.   Autophagy

Therapeutic strategies targeting cancer stem cells

(2015) Go J. Yoshida et al.   CANCER SCIENCE

Metabolic reprogramming: the emerging concept and associated therapeutic strategies

(2015) Go J. Yoshida   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The prognostic impact of high Nijmegen breakage syndrome (NBS1) gene expression in ERG-negative prostate cancers lacking PTEN deletion is driven by KPNA2 expression

(2014) Katharina Grupp et al.   INTERNATIONAL JOURNAL OF CANCER

Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation

(2013) Go J. Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Understanding high grade glioma: Molecular mechanism, therapy and comprehensive management

(2013) Yongzhi Wang et al.   CANCER LETTERS

Quantitative Proteomics Reveals Regulation of Karyopherin Subunit Alpha-2 (KPNA2) and Its Potential Novel Cargo Proteins in Nonsmall Cell Lung Cancer

(2012) Chun-I Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

High Expression of Karyopherin-α2 Defines Poor Prognosis in Non–Muscle-Invasive Bladder Cancer and in Patients with Invasive Bladder Cancer Undergoing Radical Cystectomy

(2011) Jørgen Bjerggaard Jensen et al.   EUROPEAN UROLOGY

MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities

(2009) C. V. Dang et al.   CLINICAL CANCER RESEARCH

Tumor suppressors and cell metabolism: a recipe for cancer growth

(2009) R. G. Jones et al.   GENES & DEVELOPMENT

The Warburg Effect Suppresses Oxidative Stress Induced Apoptosis in a Yeast Model for Cancer

(2009) Christoph Ruckenstuhl et al.   PLoS One

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism