4.1 Article

Latest Progress in Microsporidian Genome Research

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JOURNAL OF EUKARYOTIC MICROBIOLOGY
卷 60, 期 3, 页码 309-312

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WILEY-BLACKWELL
DOI: 10.1111/jeu.12030

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Fungi; heterozygosity; horizontal gene transfers; microsporidian phylogeny

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Microsporidia are obligate intracellular pathogens of medical and ecological importance whose genomes have been studied extensively over the last decade. Such studies have focused on the remarkably reduced gene content that characterizes all known species, and some have unraveled the mechanisms that are involved in their extreme genome compaction. In the last year, a large number of new genome sequences from several divergent members of the group have been finally released and analyzed, and these have revealed the presence of many features that were previously unsuspected to exist within the group. This study aims to shortly review the most recent progress in the field of microsporidian genomics, highlighting the importance of the most recently released genome data for our understanding of the biology and evolution of this important group of parasites.

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