期刊
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
卷 29, 期 5, 页码 647-653出版社
INFORMA HEALTHCARE
DOI: 10.3109/14756366.2013.837899
关键词
Anti-bacterial; methicillin-resistant Staphylococcus aureus; rhodanine
资金
- National Science Foundation of China [81260468]
Herein, we report the design, syntheses and in vitro anti-microbial activity of two series of rhodanines with chalcone moiety. Anti-microbial tests showed that some of the synthesized compounds exhibited good inhibition (MIC = 1-8 mu g/mL) against multi-drug-resistant Gram-positive organisms, including methicillin resistant and quinolone-resistant Staphylococcus aureus, in which the compound 4g was found to be the most potent with minimum inhibitory concentration (MIC) value of 1 mu g/mL against two methicillin-resistant S. aureus.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据