The Role of Cadmium and Nickel in Estrogen Receptor Signaling and Breast Cancer: Metalloestrogens or Not?

Dietary Cadmium Exposure and Risk of Postmenopausal Breast Cancer: A Population-Based Prospective Cohort Study

(2012) B. Julin et al.   CANCER RESEARCH

A Cross-Talk Between NFAT and NF-κB Pathways is Crucial for Nickel- Induced COX-2 Expression in Beas-2B Cells

(2012) T. Cai et al.   CURRENT CANCER DRUG TARGETS

Exposure to cadmium chloride influences astrocyte-elevated gene-1 (AEG-1) expression in MDA-MB231 human breast cancer cells

(2011) Claudio Luparello et al.   BIOCHIMIE

Trace Elements and Heavy Metals in Hair of Stage III Breast Cancer Patients

(2011) Yasemin Benderli Cihan et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Structural and thermodynamic consequences of the replacement of zinc with environmental metals on estrogen receptor α-DNA interactions

(2011) Brian J. Deegan et al.   JOURNAL OF MOLECULAR RECOGNITION

Effects of Nickel Treatment on H3K4 Trimethylation and Gene Expression

(2011) Kam-Meng Tchou-Wong et al.   PLoS One

Histone Deacetylase 6 Regulates Estrogen Receptor α in Uterine Leiomyoma

(2011) Lin-Hung Wei et al.   Reproductive Sciences

Nickel-induced down-regulation of ΔNp63 and its role in the proliferation of keratinocytes

(2011) Zhuo Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Estrogen Receptor-beta Mediates the Protective Effects of Aromatase Induction in the MMTV-Her-2/neu x Aromatase Double Transgenic Mice

(2011) Hareesh B. Nair et al.   Hormones & Cancer

Cadmium concentration in biological media of breast cancer patients

(2010) Loreta Strumylaite et al.   BREAST CANCER RESEARCH AND TREATMENT

Nuclear Alternate Estrogen Receptor GPR30 Mediates 17 -Estradiol-Induced Gene Expression and Migration in Breast Cancer-Associated Fibroblasts

(2010) A. Madeo et al.   CANCER RESEARCH

The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells

(2010) E. A. Ariazi et al.   CANCER RESEARCH

Reactive Oxygen Species-Activated Akt/ASK1/p38 Signaling Pathway in Nickel Compound-Induced Apoptosis in BEAS 2B Cells

(2010) Jingju Pan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Estrogen-Like Effects of Cadmium in Vivo Do Not Appear to be Mediated via the Classical Estrogen Receptor Transcriptional Pathway

(2010) Imran Ali et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cadmium Promotes Breast Cancer Cell Proliferation by Potentiating the Interaction between ERα and c-Jun

(2010) Christina L. Siewit et al.   MOLECULAR ENDOCRINOLOGY

Arsenic abrogates the estrogen-signaling pathway in the rat uterus

(2010) Aniruddha Chatterjee et al.   Reproductive Biology and Endocrinology

The membrane estrogen receptor GPR30 mediates cadmium-induced proliferation of breast cancer cells

(2010) Xinyuan Yu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Heterochromatinization as a Potential Mechanism of Nickel-Induced Carcinogenesis

(2009) Thomas P. Ellen et al.   BIOCHEMISTRY

Cadmium effects on p38/MAPK isoforms in MDA-MB231 breast cancer cells

(2009) Caterina Casano et al.   BIOMETALS

Effects of Nickel on Cyclin Expression, Cell Cycle Progression and Cell Proliferation in Human Pulmonary Cells

(2009) J. Ding et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

(2009) Deo Prakash Pandey et al.   EMBO JOURNAL

Population Toxicokinetic Modeling of Cadmium for Health Risk Assessment

(2009) Billy Amzal et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cadmium Malignantly Transforms Normal Human Breast Epithelial Cells into a Basal-like Phenotype

(2009) Lamia Benbrahim-Tallaa et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Epigenetics in metal carcinogenesis: nickel, arsenic, chromium and cadmium

(2009) Adriana Arita et al.   Metallomics

Mechanisms of estrogen signaling and gene expression via GPR30

(2009) Eric R. Prossnitz et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Cadmium — A metallohormone?

(2009) Celia Byrne et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Dose- and route-dependent hormonal activity of the metalloestrogen cadmium in the rat uterus

(2009) Nicola Höfer et al.   TOXICOLOGY LETTERS

Estrogen Signaling through the Transmembrane G Protein–Coupled Receptor GPR30

(2008) Eric R. Prossnitz et al.   Annual Review of Physiology

Cadmium regulation of apoptotic and stress response genes in tumoral and immortalized epithelial cells of the human breast

(2008) Rosalia Sirchia et al.   BIOCHIMIE

Mechanisms of cytotoxicity of nickel ions based on gene expression profiles

(2008) Xiaoying Lü et al.   BIOMATERIALS

The G Protein-Coupled Receptor GPR30 Inhibits Human Urothelial Cell Proliferation

(2008) Jian Teng et al.   ENDOCRINOLOGY

Comparison of gene expression profiles in HepG2 cells exposed to arsenic, cadmium, nickel, and three model carcinogens for investigating the mechanisms of metal carcinogenesis

(2008) Koji Kawata et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKα-dependent cyclin D1 down-regulation

(2008) Weiming Ouyang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effects of cadmium chloride on some mitochondria-related activity and gene expression of human MDA-MB231 breast tumor cells

(2008) Giuseppe Cannino et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Global DNA hypomethylation, rather than reactive oxygen species (ROS), a potential facilitator of cadmium-stimulated K562 cell proliferation

(2008) Dejun Huang et al.   TOXICOLOGY LETTERS

Effects of cadmium on estrogen receptor mediated signaling and estrogen induced DNA synthesis in T47D human breast cancer cells

(2008) Yu Zang et al.   TOXICOLOGY LETTERS

GPR30 Contributes to Estrogen-Induced Thymic Atrophy

(2007) Chunhe Wang et al.   MOLECULAR ENDOCRINOLOGY

Nickel compounds induce histone ubiquitination by inhibiting histone deubiquitinating enzyme activity

(2007) Q KE et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Rapid activation of ERK1/2 and AKT in human breast cancer cells by cadmium

(2007) Zhiwei Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY