Editorial Material
Immunology
Ana Paula Streling, Mohanad M. Al Obaidi, William D. Lainhart, Tirdad Zangeneh, Ayesha Khan, An Q. Dinh, Blake Hanson, Cesar A. Arias, William R. Miller
Summary: A study reported the emergence of non-susceptibility to cefiderocol in a subpopulation of Pseudomonas aeruginosa recovered from a patient without prior exposure to the antibiotic. Whole genome sequencing revealed mutations in major iron transport pathways linked to cefiderocol uptake, highlighting the importance of susceptibility testing before therapy with siderophore cephalosporins.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Aysegul Copur Cicek, Ayse Erturk, Nebahat Ejder, Erva Rakici, Ugur Kostakoglu, Ilknur Esen Yildiz, Songul Ozyurt, Emine Sonmez
Summary: Researching carbapenem-resistant isolates revealed a high prevalence of bacteria carrying beta-lactamase and metallo-beta-lactamase genes, with more resistance genes and coexistence found in hospital-acquired samples. There was no difference between community and hospital-associated isolates in PFGE results, but a significant difference was observed in terms of fatality rates, indicating the importance of other microorganisms coexisting with resistance genes in patient outcomes.
INFECTION AND DRUG RESISTANCE
(2021)
Article
Veterinary Sciences
Telma de Sousa, Andreia Garces, Augusto Silva, Ricardo Lopes, Nuno Alegria, Michel Hebraud, Gilberto Igrejas, Patricia Poeta
Summary: This study evaluated the antimicrobial resistance patterns and biofilm production of clinical isolates of pathogenic bacterium Pseudomonas aeruginosa in dogs. The results revealed widespread resistance to beta-lactam antimicrobials, with amikacin and tobramycin being the only effective aminoglycosides. All isolates carried the oprD gene and virulence genes. The study emphasizes the importance of monitoring antimicrobial resistance and responsible antibiotic use in veterinary medicine to prevent multi-drug resistance.
VETERINARY SCIENCES
(2023)
Article
Environmental Sciences
Katja Kehl, Anja Schallenberg, Christiane Szekat, Cathrin Albert, Esther Sib, Martin Exner, Nicole Zacharias, Christiane Schreiber, Marjio Parcina, Gabriele Bierbaum
Summary: The study identified carbapenem-resistant bacteria in the wastewater of a large hospital, with high-risk clones potentially being directly disseminated into the environment. Two possible transmission pathways were identified, highlighting the need for remediation measures at both ends of the wastewater system.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Infectious Diseases
Seryoung Kim, Satomi Masai, Keiji Murakami, Momoyo Azuma, Keiko Kataoka, Mayu Sebe, Kazuya Shimizu, Tomoaki Itayama, Niwooti Whangchai, Kanda Whangchai, Ikko Ihara, Hideaki Maseda
Summary: This study established an isolation method to evaluate the infection risk of Pseudomonas aeruginosa in the environment using specific culture conditions and primers. The results showed clear differences between environmental and clinical strains, but both had a high potential resistance risk for non-resistant strains.
Article
Biochemistry & Molecular Biology
Adeline Cezard, Delphine Fouquenet, Virginie Vasseur, Katy Jeannot, Fabien Launay, Mustapha Si-Tahar, Virginie Herve
Summary: By using scanning electron microscopy and fluorometry test, this study demonstrated that poly-L-lysine can enhance the bactericidal effects of commonly used antibiotics against drug-resistant Pseudomonas aeruginosa. The synergistic effects of the combination were confirmed in vitro and ex vivo, suggesting that pLK could be a potential adjuvant antibiotherapy against drug-resistant strains.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Virology
Bahareh Lashtoo Aghaee, Mohammadali Khan Mirzaei, Mohammad Yousef Alikhani, Ali Mojtahedi, Corinne F. Maurice
Summary: Antibiotic resistance is a significant global threat, and using a combination of phages and antibiotics may be an effective strategy for treating multidrug-resistant Pseudomonas aeruginosa infections.
Article
Immunology
Wenlu Zhang, Shasha Li, Bo Deng, Pengfei Wu, Yingbin Shui, Jiaming Zhang, Zhongjie Li
Summary: This study used RNA-sequencing to analyze sRNAs in antibiotic-resistant PAO1, finding a large number of differentially expressed sRNAs. Target gene prediction and pathway analysis revealed the potential roles of these differentially expressed sRNAs in regulating antibiotic resistance.
MICROBIAL PATHOGENESIS
(2022)
Article
Engineering, Environmental
Farzaneh Baghal Asghari, Mohammad Hadi Dehghani, Reza Dehghanzadeh, Davoud Farajzadeh, Kamyar Yaghmaeian, Amir Hossein Mahvi, Akbar Rajabi
Summary: This research characterized the microbial populations and resistant genes in hospital wastewater, finding high concentrations of HPC and ARB, with high resistance rates to Sulfamethoxazole and ceftazidime, and high sensitivity to gentamicin. SulCYRILLIC CAPITAL LETTER BYELORUSSIAN-UKRAINIAN I and QnrS were identified as the most and least abundant ARGs, respectively, with bla(SHV) being the most prevalent beta-lactam resistant gene.
WATER SCIENCE AND TECHNOLOGY
(2021)
Article
Environmental Sciences
Nikola Roulova, Petra Mot'kova, Iveta Brozkova, Marcela Pejchalova
Summary: This study evaluated the antibiotic resistance profiles of Pseudomonas aeruginosa in untreated hospital effluents in the Czech Republic. The findings revealed the presence of antibiotic-resistant strains in hospital wastewater that were resistant to clinically relevant antipseudomonal drugs. Inadequate treatment of hospital wastewater can lead to the direct release of resistant bacteria into public sewer networks, potentially facilitating the spread of antibiotic resistance.
JOURNAL OF WATER AND HEALTH
(2022)
Article
Chemistry, Analytical
Zahra Rafiee, Seokheun Choi
Summary: A reliable and rapid AST device was developed to monitor bacterial growth and treatment efficacy in biofilm-based infections. The device measures changes in electrical outputs to assess the effectiveness of antibiotic treatment against pathogenic biofilms.
Article
Biochemistry & Molecular Biology
Karolina Anna Mielko, Slawomir Jan Jablonski, Lukasz Pruss, Justyna Milczewska, Dorota Sands, Marcin Lukaszewicz, Piotr Mlynarz
Summary: The research compared the metabolisms of two P. aeruginosa strains, showing that the differences between drug-resistant and drug-susceptible strains mainly lie in the turnover of amino acids. This study provides valuable information to complement research on drug resistance in P. aeruginosa.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Microbiology
Damien Fournier, Romain Carriere, Maxime Bour, Emilie Grisot, Pauline Triponney, Cedric Muller, Jerome Lemoine, Katy Jeannot, Patrick Plesiat
Summary: This study evaluated the resistance mechanisms of Pseudomonas aeruginosa to ceftolozane/tazobactam, identifying strains with various resistance genes and high production of cephalosporinase PDC. It also found mutations in regulatory genes and enzymes contributing to resistance, highlighting the importance of both intrinsic and transferable mechanisms in C/T-resistant P. aeruginosa.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Chemistry, Multidisciplinary
Cansu Kaya, Isabell Walter, Samir Yahiaoui, Asfandyar Sikandar, Alaa Alhayek, Jelena Konstantinovic, Andreas M. Kany, Jorg Haupenthal, Jesko Koehnke, Rolf W. Hartmann, Anna K. H. Hirsch
Summary: Extracellular virulence factors, including the LasB enzyme secreted by the Gram-negative pathogen Pseudomonas aeruginosa, have become important targets in the current antimicrobial resistance crisis. In this study, a sub-micromolar, non-peptidic inhibitor of LasB was discovered through structural data analysis and optimization, showing improved in vivo efficacy in Galleria mellonella larvae. This class of compounds shows promise as potential drug candidates for combating infections.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Review
Biochemistry & Molecular Biology
Claudia Verdial, Isa Serrano, Luis Tavares, Solange Gil, Manuela Oliveira
Summary: Pseudomonas aeruginosa is a highly adaptable bacterial pathogen that can cause infections in both human and veterinary medicine. It is capable of surviving in different environments and colonizing inert materials, as well as developing various phenotypes to persist, including antimicrobial-tolerant strains, persister cells, and biofilms. The emergence of pathogenic strains that are resistant to antibiotics and biocides is a major global concern, and the effectiveness of biocide use is hindered by the development of tolerance.
Article
Environmental Sciences
Elizabeth Alvarez-Chavez, Stephane Godbout, Mylene Genereux, Caroline Cote, Alain N. Rousseau, Sebastien Fournel
Summary: This study evaluated the effect of alternative filtering materials and bed aeration on the retention of nutrients and fecal bacteria in woodchip bedded stand-off pads for cows. The results showed that the alternative biofilters were more efficient in removing COD, SS, TN, and NO3-N, while conventional biofilters were more efficient for PO4-P removal. Aeration did not have a significant effect under the tested temperature conditions.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Yike Zhang, Zengyi Ma, Zhuoting Fang, Yuandong Qian, Zhiping Huang, Yilong Ye, Jianhua Yan
Summary: This study investigates the application of oxygen enrichment melting technology in the melting of municipal solid waste incineration fly ash. The results demonstrate that oxygen enrichment technology can reduce energy consumption and operating costs, as well as decrease pollution emissions.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Liangang Xiao, Mingkai Leng, Philip Greenwood, Rongqin Zhao, Zhixiang Xie, Zengtao You, Junguo Liu
Summary: This study investigates the effects of grazing exclusion on soil organic carbon (SOC) accumulation and vegetation recovery. It finds that grazing exclusion can increase the potential for SOC accumulation, and higher annual precipitation is positively correlated with SOC accumulation.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Beatrice Cantoni, Jessica Ianes, Beatrice Bertolo, Selena Ziccardi, Francesco Maffini, Manuela Antonelli
Summary: This study evaluates the performance of ozonation and adsorption as in-series processes compared to standalone processes for the removal of Contaminants of Emerging Concern (CECs) in drinking water. The combination of both processes proves to be more effective than adsorption and ozonation alone. Ozonation improves the adsorption performance of poorly-oxidizable CECs but worsens that of well-oxidizable compounds. This research highlights the importance of considering both processes in the removal of CECs in drinking water treatment plants.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Dan Li, Bingjun Liu, Yang Lu, Jianyu Fu
Summary: A new Standardized compound Drought and Saltwater intrusion Index (SDSI) was developed to detect changes in the severity of CDSEs in six estuaries. The study found that saltwater intrusion plays a dominant role in influencing SDSI severity, and CDSEs vary in frequency, duration and severity among different estuaries.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Yong-Qiang Li, Rui Sun, Chong-Miao Zhang, Zi-Xuan Liu, Rui-tao Chen, Jian Zhao, Hua-dong Gu, Huan-Cai Yin
Summary: In this study, an electron beam excitation multi-wavelength ultraviolet (EBE-MW-UV) system was established and found to have significantly higher microbial inactivation effects compared to single-wavelength UV-LEDs in water. Mechanism analysis revealed that EBE-MW-UV damaged microbial DNA and proteins, and generated additional reactive oxygen species, leading to microbial inactivation.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Kaili Ma, Xinxin Han, Qiujuan Li, Yu Kong, Qiaoli Liu, Xu Yan, Yahong Luo, Xiaopin Li, Huiyang Wen, Zhiguo Cao
Summary: This study reveals that the use of a tryptophan-degrading microbial consortium (TDC) can enhance the hydrolysis efficiency of waste activated sludge (WAS), increasing the yield and quality of short chain fatty acids (SCFAs) and improving the solubilization and release of organic substances from WAS.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Ling Xiong, Rui Li
Summary: Incorporating Ecosystem Service Value (ESV) into land use planning can provide informed land management decisions. This study evaluates the ESV of Guizhou Province in China's karst region. The results show an increase in total ESV over the past two decades due to ecological restoration projects.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
M. Geetha Jenifel
Summary: This article discusses the importance of water and the pollution of freshwater resources, and introduces the use of machine learning models and blockchain technology to predict and protect water quality.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Stanslaus Terengia Materu, Taotao Chen, Chang Liu, Daocai Chi, Meng Jun
Summary: The study showed that H2SO4-modified biochar can reduce P leaching, increase soil available P, and enhance plant P uptake in alternate wetting and drying irrigation systems. Biochar additions B20A and IAWDB20A-M were effective in improving yield, reducing P leaching, and increasing APB.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Amir Nouri, Ali Akbar Zinatizadeh, Sirus Zinadini, Mark Van Loosdrecht
Summary: This study focuses on the development of an air-lift bio-electrochemical reactor (ALBER) with a continuous feeding regime to enhance nitrogen removal from synthetic wastewater. The effect of temperature, hydraulic retention time (HRT), N -NH+4 /TN ratio, and current density on the reactor performance was investigated, and the ALBER achieved a maximum TN removal of 73%. The results suggest that the ALBER has potential for treating industrial wastewater at low temperatures.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Peifang Wang, Guoxiang You, Yang Gao, Juan Chen, Xun Wang, Chao Wang
Summary: This study investigated the ecological processes of microbial communities and N- and P-transformation processes in multistage agricultural drainage ditches. The results showed that the microbial communities were co-shaped by agricultural practices and ditch size, which further governed the N and P removal performance.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Xiaofeng Niu, Huan Wang, Tao Wang, Peiyu Zhang, Huan Zhang, Hongxia Wang, Xianghong Kong, Songguang Xie, Jun Xu
Summary: Microorganisms play a critical role in maintaining ecosystem balance, and environmental stressors can affect the assembly processes of microbial communities. The study found that different stressors have opposite effects on microbial community assembly in water and sediment, and warming has different influences compared to herbicides and nutrients.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Yuqing Tan, Qiming Cheng, Fengwei Lyu, Fei Liu, Linhao Liu, Yihong Su, Shaochun Yuan, Wenyu Xiao, Zhen Liu, Yao Chen
Summary: The exacerbation of global warming, extreme weather events, and rapid urbanization have led to increased flooding in urban areas. China has adopted sponge city as an efficient means of preventing and controlling urban floods. Using a SWMM-FVCOM model, the hydrological reduction and control effect of sponge city construction (SPCC) within a university campus were evaluated. The study found that implementing SPCC effectively mitigates surface runoff and reduces the severity of urban flooding. However, the efficacy of runoff control decreases with longer rainfall return periods.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)
Article
Environmental Sciences
Zhonghan Chen, Qiuyan Li, Shibo Yan, Juan Xu, Qiaoyun Lin, Zhuangming Zhao, Ziying He
Summary: Tidal rivers are important biochemical reaction channels, receiving carbon from wastewater and agricultural drains, affecting CO2 emissions. Through modeling and data analysis, researchers explored carbon distribution, emissions, and greenhouse effects, emphasizing the potential of river management to change global CO2 emissions under climate change.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2024)