Article
Dentistry, Oral Surgery & Medicine
Laise Pena Braga Monteiro, Sergio Emilio Miranda de Sousa, Roberta Fonseca de Castro, Emmanuel Joao Nogueira Leal da Silva, Juliana Melo da Silva Brandao
Summary: This study aimed to evaluate the effectiveness of passive ultrasonic irrigation (PUI) compared to mechanical activation with Easy Clean in the removal of organic tissue from simulated areas of internal root resorption. The results showed that Easy Clean was more effective than PUI in removing organic tissue from simulated internal resorption.
Article
Dentistry, Oral Surgery & Medicine
Poliana Amanda Oliveira Silva, Stella Maris de Freitas Lima, Mirna de Souza Freire, Andre Melro Murad, Octavio Luiz Franco, Taia Maria Berto Rezende
Summary: The study identified 123 different proteins from pulp tissue, with a higher abundance of proteins related to immune response, multi-organism process, platelet activation, and stress in inflamed pulp compared to healthy pulp. Necrotic pulp showed a higher abundance of proteins related to metabolism, transport, and response between organisms compared to inflamed pulp.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Pharmacology & Pharmacy
Minjee Kwon, Il Young Jung, Myeounghoon Cha, Bae Hwan Lee
Summary: Pulpitis causes changes in the peripheral nervous system, leading to hyperalgesia. Experimental pulpitis activates Nav1.7 expression peripherally and affects TG neuronal activity. Inhibition of the Nav1.7 channel can modulate nociceptive signal processing in the TG following pulp inflammation.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Medicine, General & Internal
Abdullah Mahmoud Riyahi
Summary: This article presents a successful treatment for internal resorption cases using bioceramic material under an operating microscope. Follow-up at 18 months showed no abnormal findings clinically and radiographically. Bioceramics have many advantages, but further long-term and large sample studies are needed in the future.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Dentistry, Oral Surgery & Medicine
Mohamed Nageh, Lamiaa A. Ibrahim, Fatma M. AbuNaeem, Engy Salam
Summary: The study evaluated the management of internal inflammatory root resorption in permanent teeth using injectable platelet-rich fibrin, showing successful clinical results and periapical healing. Cone-beam computed tomography imaging revealed significant volumetric differences preoperatively and after the 12-month follow-up period.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Chemistry, Multidisciplinary
Alessio Zanza, Rodolfo Reda, Giuseppe Familiari, Stefania Annarita Nottola, Dario Di Nardo, Luca Testarelli, Orlando Donfrancesco
Summary: This study assessed surface alterations of four reciprocating instruments before and after shaping resin-simulated root canals, showing significant differences in cutting edges for one instrument and higher presence of debris for another after simulated use.
APPLIED SCIENCES-BASEL
(2022)
Article
Infectious Diseases
Giovanni Mergoni, Maddalena Manfredi, Pio Bertani, Tecla Ciociola, Stefania Conti, Laura Giovati
Summary: Enterococcus faecalis is a common cause of biofilm-associated infections, and two antifungal peptides showed promising activity in inhibiting E. faecalis biofilm formation. L18R demonstrated better anti-biofilm and bactericidal effects, while also showing no cytotoxicity to murine fibroblasts.
Article
Biotechnology & Applied Microbiology
Michael Ranniery Garcia Ribeiro, Hudson Guterres Guilherme, Alina Neres Braga, Afonso Gomes Abreu, Erika Martins Pereira, Vandilson Rodrigues, Jose Bauer, Soraia de Fatima Carvalho Souza
Summary: This study evaluated the properties and biocompatibility of an experimental endodontic repair cement containing 45S5 bioactive glass. The cement showed good physicochemical characteristics, including compressive strength, modulus of elasticity, radiopacity, pH stability, and ion release. Inflammatory reactions decreased over time, indicating a favorable biological response. Histological analysis revealed that the cement promoted new bone formation, suggesting its potential as a bioactive endodontic repair material.
BIOTECHNOLOGY LETTERS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Matheus Nogueira da Hora, Lucas de Paula Lopes Rosado, Frederico Sampaio Neves, Ieda Crusoe-Rebello, Taruska Ventorini Vasconcelos
Summary: This study compared the diagnostic efficacy of different devices in detecting simulated internal root resorption (IRR) and found that the sensitivity and accuracy values were higher with the use of Android Tablet, while lower results were observed with the iMac. Furthermore, the size of the lesion interferes with the detection capacity in the image, but the use of portable devices does not impair the diagnosis of IRR.
DENTOMAXILLOFACIAL RADIOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Fatemeh Mokhtari, Jalil Modaresi, Abbas Bagheri
Summary: This in vitro study aimed to evaluate the effect of blood contamination on the marginal adaptation of CC and MTA Angelus. The results showed that CC had significantly better marginal adaptation than MTA Angelus when contaminated with blood.
Article
Chemistry, Physical
Emmanuel J. N. L. Silva, Jorge N. R. Martins, Natasha C. Ajuz, Henrique S. Antunes, Victor T. L. Vieira, Francisco M. Braz Fernandes, Felipe G. Belladonna, Marco A. Versiani
Summary: This study compared three endodontic rotary systems in terms of design, metallurgy, and mechanical performance, and evaluated their shaping ability in simulated root canals. The results revealed similarities and differences in the design and material properties of the instruments, but their shaping ability was similar and without clinically significant errors.
Article
Materials Science, Multidisciplinary
K. E. Nygren, A. Nagao, S. Wang, P. Sofronis, I. M. Robertson
Summary: Internal hydrogen has a significant effect on the fatigue lifetime of SUS316L stainless steel, but a minimal impact on the tensile properties. The influence of hydrogen on the microstructural state and deformation twins results in non-linear changes in fatigue lifetime with increasing hydrogen concentration.
Article
Engineering, Biomedical
S. Kosumcu Akdere, Z. Ugur Aydin, D. Erdonmez
Summary: This study compared the antibacterial efficacy of different irrigation activation methods on teeth with simulated internal root resorption (IRR) and contaminated with Enterococcus faecalis (E. faecalis) using confocal laser scanning microscopy (CLSM). The results showed that there was no significant difference in bacterial elimination between the tested methods. Among the methods, PIPS showed a higher percentage of dead bacteria in the middle region compared to the apical region.
LASERS IN MEDICAL SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Izabela Potocka, Joanna Szymanowska-Pulka
Summary: This study examined the impact of mechanical stress on the pellicle of grass roots. Results showed that while mechanical stress caused microdamage in the epidermal layers, the pellicle played a protective role in preventing damage to the protodermal cells, thereby safeguarding the root apical meristem from negative effects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemical Research Methods
Tong Xin, Yanan Lv, Haoran Chen, Linlin Li, Lijun Shen, Guangcun Shan, Xi Chen, Hua Han
Summary: This article proposes a new method for serial section registration using an unsupervised optical flow network to measure feature similarity and eliminate nonlinear deformation. The optical flow network is also used to estimate and compensate for cumulative registration error, enabling the reconstruction of biological tissue structures. Experimental results demonstrate that this method effectively improves the spatial continuity of serial sections and enhances the accuracy of registration and reconstruction for biological tissue structures.
Article
Dentistry, Oral Surgery & Medicine
Sang Won Kwak, Jung-Hong Ha, Ya Shen, Markus Haapasalo, Hyeon-Cheol Kim
Summary: Glide-path preparation and coronal pre-flaring can reduce torque generation, which is advantageous for reducing stress and reactive forces to NiTi files and root dentin.
AUSTRALIAN ENDODONTIC JOURNAL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Wenjuan Zhang, He Liu, Zhejun Wang, Markus Haapasalo, Qianzhou Jiang, Ya Shen
Summary: The efficiency of retreatment in oval-shaped canals using a tricalcium silicate sealer is closely related to storage time rather than filling technique. The XPFR instrument is effective in removing remaining materials from oval-shaped canals.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Hind Al-Zuhair, Zheng Su, He Liu, Zhejun Wang, Markus Haapasalo, Ahmed Hieawy, Yuan Gao, Ya Shen
Summary: This study compared the antibacterial effects of different agitation devices on single- and multispecies biofilms in dentin canals. The results showed that agitating NaOCl can more effectively kill biofilms. EDDY was as effective as PUI when combined with NaOCl, but the antimicrobial efficiency in the apical portion was still a concern.
Article
Dentistry, Oral Surgery & Medicine
Evan Baird, Xiangya Huang, He Liu, Ahmed Hieawy, N. Dorin Ruse, Zhejun Wang, Markus Haapasalo, Ya Shen
Summary: A dynamic model was developed to evaluate the fatigue resistance of instruments at body temperature. The study found that the combination of rotational and axial movement led to greater fatigue resistance compared to rotational movement alone. Additionally, the curvature near the apex had a greater impact on fatigue resistance than curvatures in the coronal and middle thirds.
AUSTRALIAN ENDODONTIC JOURNAL
(2023)
Article
Engineering, Biomedical
Yue Xu, Yuan You, Luyao Yi, Xiaoyi Wu, Yaning Zhao, Jian Yu, He Liu, Ya Shen, Jingmei Guo, Cui Huang
Summary: A stimuli-responsive multidrug delivery system has been developed in this study, which can prevent tooth decay and promote enamel restoration. The system can identify cariogenic conditions, intelligently release drugs, and restore the microarchitecture and mechanical properties of demineralized teeth.
BIOACTIVE MATERIALS
(2023)
Article
Engineering, Biomedical
Fushi Wang, Xinjie Cai, Ya Shen, Liuyan Meng
Summary: This review discusses the effects of various types of scaffold materials on cell-scaffold interaction in tissue engineering. It elaborates on the influence of the physical, chemical, mechanical, and biological characteristics of scaffold materials on cell-scaffold interaction. The review also examines the role of scaffold components, degradation process, and degraded products in cell-scaffold interactions. Furthermore, it summarizes the latest research progress on cell-scaffold interactions among various engineered tissues or organs in the oral and craniofacial region.
BIOACTIVE MATERIALS
(2023)
Article
Engineering, Biomedical
Jian Yu, Haolin Bian, Yaning Zhao, Jingmei Guo, Chenmin Yao, He Liu, Ya Shen, Hongye Yang, Cui Huang
Summary: As a global public health focus, oral health plays a vital role in overall health. Defected teeth with exposed dentin increase the risk of oral diseases such as hypersensitivity and inflammation. The E/PA@HMS nanosystem effectively occludes dentinal tubules, inhibits biofilm formation, induces collagen mineralization, and promotes odontogenic differentiation and mineralization of dental pulp cells. Animal experiments demonstrate its long-lasting effects in sealing tubules and inhibiting biofilm growth. This nanosystem shows promising benefits for protecting exposed dentin.
BIOACTIVE MATERIALS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jinghao Hu, Jian Yu, He Liu, Zhejun Wang, Markus Haapasalo, Evan F. Haney, Robert E. W. Hancock, Shuli Deng, Ya Shen
Summary: This study evaluated the antimicrobial effects of commercially available mouthrinses and a D-enantiomeric peptide on oral multispecies biofilms. The results showed that DJK-5 demonstrated the highest percentage of dead bacteria and may be a potential candidate for future mouthrinses.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
He Liu, Stefanie Nio, Ya Shen
Summary: This study evaluated the efficacy of different concentrations of sodium hypochlorite at various exposure times and temperatures against Enterococcus faecalis biofilms in human dentinal tubules. The results showed no significant differences in effectiveness between the 2% and 5.25% sodium hypochlorite solutions at different temperatures or exposure times. Increasing the temperature or exposure time of sodium hypochlorite was found to be more important than raising its concentration to optimize its effectiveness in killing E. faecalis while minimizing potential damage.
Article
Materials Science, Multidisciplinary
Jihye Hong, Sang Won Kwak, Jung-Hong Ha, Asgeir Sigurdsson, Ya Shen, Hyeon-Cheol Kim
Summary: This study compared the fatigue resistance of files made from different heat treatment methods and surface treatment. Four prototype files were created and tested, and it was found that the file that underwent a specific temperature heat treatment with titanium coating surface treatment showed the highest fatigue resistance.
Article
Infectious Diseases
Luana Dutra de Carvalho, Bernardo Urbanetto Peres, Ya Shen, Markus Haapasalo, Hazuki Maezono, Adriana P. Manso, Frank Ko, John Jackson, Ricardo M. Carvalho
Summary: This study successfully encapsulated and controlled the release of chlorhexidine using cellulose acetate nanofibers as a drug carrier for the treatment of dental bacterial infections. The nanofiber mats produced were thin, flexible and strong, allowing for intimate contact with surfaces and effective bacterial killing.
Article
Medicine, General & Internal
Ying Li, Zhengyang Wang, Pingping Bao, Tingting Meng, Meng Liu, Huixu Li, Ya Shen, Dayong Liu, Zhi Jia, He Liu
Summary: This study aimed to compare the cleaning and disinfecting efficiency of oval-shaped root canals using XP-endo Shaper (XPS), ProTaper Next (PTN), and HyFlex CM (HCM) in combination with passive ultrasonic irrigation (PUI). Results showed that XPS outperformed PTN and HCM in disinfecting the root canals. However, removing hard tissue debris from the critical apical area remained challenging.
MEDICINA-LITHUANIA
(2023)
Article
Dentistry, Oral Surgery & Medicine
Dan Wang, Jian Yu, He Liu, Tian Zhang, Evan F. Haney, Robert E. W. Hancock, Lin Peng, Ya Shen
Summary: This study aimed to investigate the effectiveness of DJK-5-D enantiomeric antibiofilm peptide on the corrosion resistance of titanium with different surface roughness. The results showed that DJK-5 effectively enhanced the corrosion resistance of titanium while killing S. mutans biofilms, with smooth surfaces more susceptible to peptide treatment.
JOURNAL OF DENTISTRY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Kayi Lui, He Liu, Hao Wang, Xueqin Yang, Dingming Huang, Xuedong Zhou, Yuan Gao, Ya Shen
Summary: The objective of this study was to develop a customized framework for evaluating registration accuracy and measuring the untouched surface area of canal instrumentation. The results showed a significant difference between manual and automatic registration, while there was no difference in the untouched surface measure methods. There was a correlation between registration accuracy and untouched surface area.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Medicine, General & Internal
Hui Zhang, Min Cai, Zhiguo Liu, He Liu, Ya Shen, Xiangya Huang
Summary: This study reported a novel autotransplantation technique using virtual simulation, CARP model-based rehearsed surgery, and tooth replica-guided surgery. The technique showed excellent stability and predictable outcomes in a complex case of dental rehabilitation.
MEDICINA-LITHUANIA
(2022)