Article
Dentistry, Oral Surgery & Medicine
Philipp Becker, Adrian Kasaj, Sven Schumann, Peer W. Kaemmerer, Daniel G. E. Thiem, Diana Heimes, Andreas Pabst
Summary: This study analyzed the biomechanical characteristics of a novel cyanoacrylate-based tissue adhesive (CTA) for soft-tissue closure in the alveolar process and around dental implants. The results showed that CTA had different biomechanical properties compared to sutures, suggesting that it could be a possible alternative for intraoral wound closure in certain conditions.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
J. J. Zhao, S. Tashi, E. J. Lim, S. Y. Wong, Y. W. Wang, R. Sultana, S. Leong, J. M. E. Chua, C. W. Too, S. Chandramohan
Summary: This study compared the peri-operative outcomes of using octyl cyanoacrylate (OCA) skin adhesive (Dermabond) for skin closure with or without subcuticular sutures after deep dermal suturing for implantable venous port placement closure. The results showed that there were no significant differences in pain scores, bleeding, swelling, bruising, fever, wound dehiscence, and discharge at postoperative day 1 (POD1) and at first follow-up between the groups.
CLINICAL RADIOLOGY
(2022)
Article
Emergency Medicine
Jennifer L. Brown, Dietrich Jehle, James Mayrose, Lainie Schwartz, Jennifer Pugh, Clay O'Brien
Summary: The study demonstrates that the combination of skin tapes and tissue adhesive provides superior immediate wound closure strength in a porcine model compared to either method alone.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Multidisciplinary Sciences
Young Hwan Park, Jeong Seok Choi, Jung Woo Choi, Hak Jun Kim
Summary: This study investigated the incidence and risk factors of allergic contact dermatitis (ACD) after using 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives. The incidence of ACD from both adhesives was around 2-3%, with no significant difference between them. Logistic regression analysis did not identify any variables that increased the risk of ACD for either adhesive, suggesting that clinicians and patients should be aware of the possibility of ACD even without known risk factors.
SCIENTIFIC REPORTS
(2021)
Article
Anesthesiology
Theerawat Chalacheewa, Vanlapa Arnuntasupakul, Lisa Sangkum, Rungrawan Buachai, Jiravud Chanvitayapongs
Summary: This study compared the efficacy of using 2-octyl cyanoacrylate glue (Dermabond (R)) and sterile strips for catheter fixation, finding that catheter fixation with adhesive glue significantly reduces the incidence of pericatheter leakage and catheter displacement.
BMC ANESTHESIOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
D. T. Wu, B. R. Freedman, K. H. Vining, D. L. Cuylear, F. P. S. Guastaldi, Y. Levin, D. J. Mooney
Summary: Oral lichen planus (OLP) and recurrent aphthous stomatitis (RAS) are common chronic inflammatory conditions causing painful oral lesions. The existing treatment methods are often ineffective due to insufficient contact time. A bioinspired adhesive patch called Dental Tough Adhesive (DenTAl) was developed, which exhibited superior physical and adhesive properties compared to current oral technologies. DenTAl can deliver clobetasol-17-propionate, a first-line drug for OLP and RAS, with extended release and demonstrated immunomodulatory capabilities in vitro.
JOURNAL OF DENTAL RESEARCH
(2023)
Article
Surgery
Barbara Perez-Kohler, Selma Benito-Martinez, Francisca Garcia-Moreno, Marta Rodriguez, Gemma Pascual, Juan Manuel Bellon
Summary: The study investigated the use of cyanoacrylate tissue adhesive to improve mesh behavior at fixation zones. Results showed that cyanoacrylate prevented bacterial adhesion, reducing infections and optimizing the efficacy of antibacterial meshes compared to those fixed with sutures.
Article
Medicine, General & Internal
Vincent Gomez, Mark Cairns, Paul Weinhold, Alexander D. Jeffs, Benjamin Bortner, Anthony Paterno, Laurence Dahners, Reid W. Draeger
Summary: The study found that the use of 2-OCTA inhibits bone healing and results in insufficient bone bridging formation, making it unsuitable for fracture fixation.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Dentistry, Oral Surgery & Medicine
Olutayo James, Adegbayi Adeola Adekunle, Wasiu Lanre Adeyemo
Summary: This study compared the efficacy of Dermabond tissue adhesive and 5/0 Prolene sutures in cleft lip repair, finding no significant difference in wound healing and cosmetic outcomes between the two groups at the 3-month follow-up.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2021)
Article
Orthopedics
Gun-Woo Lee, Woo Kyoung Kwak, Keun-Bae Lee
Summary: In patients undergoing total ankle arthroplasty, skin adhesive showed better patient satisfaction for wound cosmesis compared to interrupted polypropylene sutures, but had significantly higher rates of wound complications.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Materials Science, Multidisciplinary
Tao Lei, Yushuang Zhao, Xinrang Zhai, Shunxian Ji, Binghua Song, Wei Dong, Chong Teng, Wei Wei
Summary: This study presents a tissue adhesive patch based on a bioadhesive hydrogel and a tough elastomer for atraumatic and rapid tissue repair. The patch demonstrates strong and sutureless sealing capabilities using ex vivo models and shows biocompatibility through in vitro and in vivo experiments. The efficiency of the patch is demonstrated in a challenging rabbit meniscus tear model. The findings suggest that this hydrogel-elastomer composite may be a promising alternative to sutures for tissue repair.
MATERIALS & DESIGN
(2023)
Article
Allergy
Chika Asai, Naoko Inomata, Megumi Sato, Nao Koh, Seiko Goda, Hideyuki Ishikawa, Masako Tanaka, Michiko Aihara
Summary: This study found that Dermabond-induced allergic contact dermatitis is characterized by a high prevalence of primary sensitization at first exposure, frequent secondary generalization, and most patients showing cross-reactivity to ethyl cyanoacrylate.
CONTACT DERMATITIS
(2021)
Article
Biophysics
Chong Shen, Yingjun Li, Qin Meng
Summary: This paper presents a PEG-based tissue patch made of F127-DA hydrogel and PEG-DA adhesive, which can be used as an alternative to sutures for repairing wounded tissues. The patch shows good tissue compatibility and can effectively seal and prevent leakage of liquid or air.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Review
Pediatrics
Sarthak Tandon, Matthew Smale, Maurizio Pacilli, Ramesh M. Nataraja
Summary: This study compared tissue adhesive (TiA), adhesive tape (AdT), and sutures for closing surgical wounds and lacerations in children, finding that AdT had slightly better cosmetic outcomes compared to TiA, while there was no significant difference in cosmesis between TiA and sutures. All three techniques showed equivalent risk of wound infection and dehiscence.
JOURNAL OF PEDIATRIC SURGERY
(2021)
Article
Chemistry, Physical
Carlota Castro-Gaspar, Maria Victoria Olmedo-Gaya, Maria Nuria Romero-Olid, Maria Jesus Lisbona-Gonzalez, Marta Vallecillo-Rivas, Candela Reyes-Botella
Summary: The study demonstrates that the use of tissue adhesive cyanoacrylate in oral surgery significantly reduces operative time and postoperative bleeding within the first 24 hours compared to sutures.