Review
Biotechnology & Applied Microbiology
Xiao Hou, Jingmin Liu, Kaixiang Weng, Lisa Griffin, Laura A. Rice, Yih-Kuen Jan
Summary: This study found that compression and LEDT have a significant effect on reducing muscle fatigue, and compression, active recovery, and cooling have a significant effect on reducing muscle fatigue when applied during exercise, but not after exercise.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Analytical
Joo Hye Sung, Seol-Hee Baek, Jin-Woo Park, Jeong Hwa Rho, Byung-Jo Kim
Summary: This study aimed to evaluate the feasibility of the surface electromyography (sEMG) parameters for estimating muscle mass. The results showed that sEMG parameters were positively correlated with maximal voluntary contraction strength, segmental lean mass, and appendicular skeletal muscle mass, but negatively correlated with segmental fat mass. Under controlled conditions, sEMG parameters can represent overall muscle strength and muscle mass in healthy individuals.
Article
Biochemistry & Molecular Biology
Javier Botella, Nicholas A. Jamnick, Cesare Granata, Amanda J. Genders, Enrico Perri, Tamim Jabar, Andrew Garnham, Michael Lazarou, David J. Bishop
Summary: Autophagy is an important mechanism for cells to degrade old or dysfunctional proteins and organelles. The effects of exercise on autophagosome content markers differ between rodents and humans. The decrease in LC3B-II protein levels induced by exercise in humans does not reflect a decreased autophagy flux.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Anjali Bhat, Rafay Abu, Sankarasubramanian Jagadesan, Neetha Nanoth Vellichirammal, Ved Vasishtha Pendyala, Li Yu, Tara L. Rudebush, Chittibabu Guda, Irving H. Zucker, Vikas Kumar, Lie Gao
Summary: Exercise training improves skeletal muscle health through various adaptative pathways. Nrf2, an important antioxidant transcription factor, is crucial for the adaptative responses and beneficial effects of exercise on muscle. The study suggests that Nrf2 plays a critical role in the adaptive effects of skeletal muscle and its response to exercise training.
Article
Medicine, General & Internal
Etienne Gouraud, Philippe Connes, Alexandra Gauthier-Vasserot, Camille Faes, Salima Merazga, Solene Poutrel, Celine Renoux, Camille Boisson, Philippe Joly, Yves Bertrand, Arnaud Hot, Giovanna Cannas, Christophe Hautier
Summary: This study investigated the relationship between muscle dysfunction and exercise capacity in sickle cell disease patients. The results suggest that the performance in the 6-MWT is primarily explained by anemia and self-paced step frequency in these patients, with no muscle fatigue observed.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Chemistry, Analytical
Yaojung Shiao, Thang Hoang
Summary: This paper presents a method to observe and evaluate muscle extension conditions using electromyography (EMG) and inertial measurement unit (IMU) sensors. The study successfully sensed a user's muscle conditions during exercise in a leg extension machine and provided proof of concept for using EMG signals to sense muscle fatigue. These results can be applied to other smart exercise machines in the future.
Article
Biochemistry & Molecular Biology
Marc Yehya, Doria Boulghobra, Pierre-Edouard Grillet, Pablo R. Fleitas-Paniagua, Patrice Bideaux, Sandrine Gayrard, Pierre Sicard, Jerome Thireau, Cyril Reboul, Olivier Cazorla
Summary: The aim of this study was to investigate the effects of four different natural extracts with recognized antioxidant properties on the contractile function of skeletal and cardiac muscles after prolonged exhausting exercise. The results showed that all natural extracts provided protection for both cardiac and skeletal muscles, with different degrees depending on muscle type and duration of recovery. These findings suggest that acute antioxidant supplementation can help protect against the toxic effects of prolonged exhausting exercise.
Article
Immunology
Catherine M. Jankowski, Melissa P. Wilson, Samantha MaWhinney, Jane Reusch, Leslie Knaub, Sara Hull, Kristine M. Erlandson
Summary: The study found that individuals with HIV had blunted mitochondrial adaptations to exercise compared to uninfected controls, suggesting the need for different types of exercise-induced stimulation to improve mitochondrial function in this population.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Review
Hospitality, Leisure, Sport & Tourism
Harrison Gallagher, Paul W. Hendrickse, Marcelo G. Pereira, T. Scott Bowen
Summary: This review discusses the mechanisms underlying skeletal muscle wasting and weakness caused by heart failure (HF). It covers topics such as protein synthesis and degradation rates, satellite cell proliferation, and calcium homeostasis. It also highlights the effects of aerobic and resistance exercise training as a beneficial treatment for HF. While exercise training can partially rescue wasting and weakness, the impact on satellite cell dynamics requires further exploration.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2023)
Article
Physiology
Cong Yin, Zewei Ma, Fan Li, Chen Duan, Yexian Yuan, Canjun Zhu, Lina Wang, Xiaotong Zhu, Songbo Wang, Ping Gao, Gang Shu, Huihua Zhang, Qingyan Jiang
Summary: This study revealed that hypoxanthine (Hx) can induce skeletal muscle fatigue and impaired exercise performance in mice through increased uncoupling protein 2 (UCP2) expression, leading to decreased energy substrate storage and enhanced glycolysis. The findings may provide insight into the pathological mechanisms of clinical muscle dysfunctions like muscle fatigue and weakness caused by abnormal metabolism.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Catherine M. Avitabile, Michael G. McBride, Xuemei Zhang, Steve Ampah, Bryan H. Goldstein, Tarek Alsaied, Samuel G. Wittekind, Kevin K. Whitehead, Babette S. Zemel, Stephen M. Paridon
Summary: Peak work rate and anaerobic activity increased with lower extremity-focused training in adolescents with Fontan circulation. However, leg lean mass did not improve. Additionally, training had no impact on physical activity questionnaire, quality of life scores, exercise cardiac magnetic resonance performance, and peripheral vascular function.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Endocrinology & Metabolism
Kristine Williams, German D. Carrasquilla, Lars Roed Ingerslev, Mette Yde Hochreuter, Svenja Hansson, Nicolas J. Pillon, Ida Donkin, Soetkin Versteyhe, Juleen R. Zierath, Tuomas O. Kilpelainen, Romain Barres
Summary: The study found that endurance exercise training remodels enhancer activity in skeletal muscle, potentially reducing the risk of chronic diseases, with exercise-induced enhancer remodeling locations also enriched in disease-associated genetic variants.
MOLECULAR METABOLISM
(2021)
Article
Biochemistry & Molecular Biology
Macsue Jacques, Shanie Landen, Javier Alvarez Romero, Danielle Hiam, Ralf B. Schittenhelm, Iresha Hanchapola, Anup D. Shah, Sarah Voisin, Nir Eynon
Summary: Exercise has significant effects on both the epigenome and proteome in human muscle. A 12-week high-intensity interval training intervention was conducted on 16 healthy moderately trained males, and muscle biopsies were collected at baseline and after 4, 8, and 12 weeks. The study found significant changes in proteins and DNA methylation levels, with some proteins consistently changed across individuals and the discovery of two novel exercise-related proteins. These findings contribute to a better understanding of the impact of exercise on the human body.
Article
Biology
Jorge Alarcon-Jimenez, Jose Enrique de la Rubia Orti, Julio Martin Ruiz, Nieves de Bernardo, Belen Proano, Carlos Villaron-Casales
Summary: This study aimed to determine muscle strength and fatigue in patients with ALS performing a unilateral exercise, and according to sex and type of ALS. The results showed more accentuated fatigue in men than in women, between the first and last contractions performed and especially on the dominant side. In addition, there was evidence of a coactivation effect on the muscles around the work joint. These findings support the use of systematic and extensive resistance exercise as a non-invasive option for maintaining the functional capacity of patients with ALS.
Article
Cell Biology
Amanda J. Genders, Jujiao Kuang, Nicholas J. Saner, Javier Botella, David J. Bishop
Summary: Exercise training can increase mitochondrial content and respiration, but high-intensity exercise may be limited by mild acidosis. This study aimed to determine the effects of administering ammonium chloride before each exercise session on mitochondrial content and respiration in rats. The results showed that ammonium chloride administration reduced the exercise-induced increase in mitochondrial respiration in the soleus muscle but did not alter mitochondrial content. These effects were not observed in the white gastrocnemius muscle.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
(2023)
Article
Sport Sciences
Mauricio Garzon, Olivier Dupuy, Laurent Bosquet, Anil Nigam, Alain Steve Comtois, Martin Juneau, Mathieu Gayda
EUROPEAN JOURNAL OF SPORT SCIENCE
(2017)
Meeting Abstract
Sport Sciences
Mauricio Garzon, Martin Juneau, Anil Nigam, Alain-Steve Comtois, Mathieu Gayda
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2016)
Meeting Abstract
Sport Sciences
Maxime Boidin, Paula A. B. Ribeiro, Meghann Monnet, Olivier Dupuy, Gabriel Lapierre, Martin Juneau, Anil Nigam, Mathieu Gayda
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2016)
Article
Hospitality, Leisure, Sport & Tourism
Mauricio Garzon, Mathieu Gayda, Anil Nigam, Alain-Steve Comtois, Martin Juneau
JOURNAL OF SPORT AND HEALTH SCIENCE
(2017)
Article
Surgery
Maria Sanz-de la Garza, Nadia Iannino, Vincent Finnerty, Asmaa Mansour, Lucie Blondeau, Mathieu Gayda, Diana Chaar, Martin G. Sirois, Normand Racine, Simon de Denus, Francois Harel, Michel White
CLINICAL TRANSPLANTATION
(2018)
Article
Multidisciplinary Sciences
Mathieu Gayda, Vincent Gremeaux, Louis Bherer, Martin Juneau, Joffrey Drigny, Olivier Dupuy, Gabriel Lapierre, Veronique Labelle, Annik Fortier, Anil Nigam
Article
Environmental Sciences
Florent Besnier, Beatrice Berube, Christine Gagnon, Miloudza Olmand, Paula Aver Bretanha Ribeiro, Anil Nigam, Martin Juneau, Lucie Blondeau, Michel White, Vincent Gremeaux, Louis Bherer, Mathieu Gayda
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Environmental Sciences
Florent Besnier, Beatrice Berube, Jacques Malo, Christine Gagnon, Catherine-Alexandra Gregoire, Martin Juneau, Francois Simard, Philippe L'Allier, Anil Nigam, Josep Iglesies-Grau, Thomas Vincent, Deborah Talamonti, Emma Gabrielle Dupuy, Hanieh Mohammadi, Mathieu Gayda, Louis Bherer
Summary: The COVID-Rehab study investigates the effectiveness of an eight-week cardiopulmonary rehabilitation program for long-term COVID-19 patients. The study examines multiple outcomes including cardiorespiratory fitness, quality of life, and cognition. The findings will provide important guidance for the rehabilitation of long-term COVID-19 patients.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Paula Aver Bretanha Ribeiro, Eve Normandin, Philippe Meyer, Martin Juneau, Michel White, Anil Nigam, Mathieu Gayda
ARQUIVOS BRASILEIROS DE CARDIOLOGIA
(2019)
Meeting Abstract
Sport Sciences
Mauricio Garzon, Mathieu Gayda, Anil Nigam, Alain-Steve Comtois, Martin Juneau
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2018)
Review
Rehabilitation
Paula A. B. Ribeiro, Maxime Boidin, Martin Juneau, Anil Nigam, Mathieu Gayda
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2017)
Article
Rehabilitation
Thibaut Guiraud, Marc Labrunee, Florent Besnier, Jean-Michel Senard, Fabien Pillard, Daniel Riviere, Lisa Richard, Davy Laroche, Frederic Sanguignol, Atul Pathak, Mathieu Gayda, Vincent Gremeaux
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2017)
Meeting Abstract
Cardiac & Cardiovascular Systems
M. Sanz, N. Iannino, V. Finnerty, F. Harel, A. Mansour, M. Gayda, D. Chaar, M. Sirois, N. Racine, M. White
EUROPEAN HEART JOURNAL
(2017)
Article
Physiology
Mathieu Gayda, Gabriel Lapierre, Olivier Dupuy, Sarah Fraser, Louis Bherer, Martin Juneau, Vincent Gremeaux, Anil Nigam
PHYSIOLOGICAL REPORTS
(2017)
Article
Rehabilitation
Paula Aver Bretanha Ribeiro, Eve Normandin, Philippe Meyer, Martin Juneau, Anil Nigam, Mathieu Gayda
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2017)
