Article
Chemistry, Analytical
Laura Sakalauskiene, Benediktas Brasiunas, Anton Popov, Asta Kausaite-Minkstimiene, Almira Ramanaviciene
Summary: The development of a first-generation reagentless amperometric glucose biosensor based on the combination of AuNS, PB, and GOx has been achieved, enabling convenient and intuitive glucose detection. The biosensor exhibits a wide linear range, good repeatability, and high selectivity.
Article
Chemistry, Analytical
Povilas Virbickas, Gerda Ziziunaite, Arunas Ramanavicius, Ausra Valiuniene
Summary: A Hg2+ ion biosensor was developed by combining Prussian blue with glucose oxidase, which can detect changes in Hg2+ ions at low potential and has a wider linear range and higher maximum detectable concentration, making it suitable for the analysis of samples with high concentration of Hg2+ ions.
Article
Chemistry, Analytical
Wisanu Niamsi, Nutcha Larpant, Pramod K. Kalambate, Vitsarut Primpray, Chanpen Karuwan, Nadnudda Rodthongkum, Wanida Laiwattanapaisal
Summary: This paper presents a novel glucose sensing platform based on a paper-based screen-printed ionic liquid/graphene electrode modified with MXene (Ti3C2Tx), prussian blue (PB), glucose oxidase (GOx), and Nafion. It has been demonstrated that the platform exhibits good correlation with the reference hexokinase method and has the potential to enhance the sensitivity and develop paper-based electroanalytical devices.
Article
Chemistry, Physical
Bin Li, Xingmin Wu, Chaosheng Shi, Yongqiang Dai, Jingfei Zhang, Wanyu Liu, Chen Wu, Yangfan Zhang, Xue Huang, Wei Zeng
Summary: The development of flexible glucose biosensors for non-invasive blood glucose monitoring through wearable devices is significant for diabetes prevention and treatment. A flexible GCGP biosensor was fabricated for sweat glucose detection, exhibiting high sensitivity and low detection limit. The biosensor showed high selectivity for glucose and good response in real sweat, attributed to the inclusion of GS.
SURFACES AND INTERFACES
(2023)
Article
Chemistry, Analytical
Maria A. Komkova, Andrei A. Eliseev, Artem A. Eliseev, Valeria S. Kasimovskaya, Andrei A. Poyarkov, Arkady A. Karyakin
Summary: We propose pulse power generation (PPG) amperometry as an advanced readout for Prussian blue (PB)-based (bio)sensors. The suggested pulse regime, which involves periodic opening and shorting of the circuit, provides a 15-fold increased signal-to-background ratio compared to the conventional continuous short-circuiting mode. The improved sensitivity and stability of the pulse readout allow reliable monitoring of blood glucose variations through sweat analysis.
ANALYTICAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Long Yan, Kunpeng Miao, Pengcheng Ma, Xiaoyan Ma, Ran Bi, Fang Chen
Summary: The highly sensitive H2O2 biosensor was successfully constructed by forming coral-like gold micro/nanostructures onto carbon cloth followed by PB electrochemical deposition. Furthermore, a glucose biosensor GOx(EA)@PB/Au/CC with high sensitivity, selectivity, reproducibility, and stability was established using the cross-linking enzyme aggregates method. The proposed biosensor was successfully applied for glucose determination in real human serum samples, demonstrating its practicality.
BIOELECTROCHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Lenys Fernandez, Jocelyne Alvarez-Paguay, Gema Gonzalez, Rafael Uribe, Diego Bolanos-Mendez, Jose Luis Pineiros, Luis Celi, Patricio J. Espinoza-Montero
Summary: In this investigation, a hydrogen peroxide (H2O2) electrochemical sensor was evaluated using a modified glassy carbon (GC) electrode. The sensor showed good electrochemical properties and could be tuned by modifying conditions and synthesis method. The coverage of TiO2-ZrO2 nanoparticles on carbon nanotubes significantly affected the immobilization and sensitivity of the electrochemical biosensor. The fabricated sensor exhibited a linear relationship between H2O2 concentration and peak current in whey milk samples.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Analytical
Joonyoung Lee, Jungyeon Ji, Kyuhwan Hyun, Heedae Lee, Yongchai Kwon
Summary: This study proposes a self-powered glucose biosensor that is flexible, disposable, and portable, allowing for quick measurement of glucose concentration with the naked eye. By utilizing the theory of enzymatic biofuel cell, this biosensor operates without the need for additional power supply and equipment to interpret glucose concentration. The biosensor demonstrates the ability to accurately measure glucose concentration even at low ranges, and has strong potential for commercial use as a glucose sensor.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Biophysics
Nicole L. Walker, Jeffrey E. Dick
Summary: The development of a new electrochemical technique - open circuit potential, has been aimed at stable and reliable monitoring of biological metabolites. By immobilizing oxidase enzyme in chitosan hydrogel, the method achieves specificity in monitoring metabolites. This approach can effectively detect metabolites such as glucose and can be extended to detect other analytes.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Physical
Jiawei Wang, Mingzhao Li, Yi Zhai, Fumin Wang, Xubin Zhang, Huihui Lv, Tiantian Yu, Weike Zhang
Summary: Constructing porous three-dimensional structures in electrode materials is an effective strategy to improve the utilization of active sites in pseudocapacitors. The study synthesized 3D NiFe Prussian blue analogue nanocubes on stainless steel mesh, demonstrating enhanced electrochemical performance and conductivity through self-built heterointerfacial interfaces. Furthermore, a hybrid supercapacitor device showed impressive electrochemical performance, providing insights for rational design of functional nanomaterials based on 3D PBAs.
APPLIED SURFACE SCIENCE
(2021)
Article
Engineering, Environmental
Changshun Xu, Danfeng Jiang, Yuancai Ge, Liping Huang, Yang Xiao, Xueqian Ren, Xiaohu Liu, Qingwen Zhang, Yi Wang
Summary: A noninvasive and continuous glucose monitoring method based on an electrochemical biosensor using PEDOT:PSS conductive hydrogel and Prussian blue nano-particles (PBNPs) is presented. The hydrogel showed low detection limit and high sensitivity, and demonstrated good accuracy in comparison to a commercial glucometer.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ausra Valiuniene, Gabija Kavaliauskaite, Povilas Virbickas, Arunas Ramanavicius
Summary: An impedimetric urea biosensor was developed in this study by modifying a fluorine doped tin oxide coated glass slide with a layer of PB and immobilizing urease. The biosensor exhibited good sensitivity to urea and a linear detectable concentration range, with investigations into the optimal conditions for stabilizing the PB layer also conducted.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Huixin Zhang, Zonghua Wang, Feng Wang, Yimeng Zhang, Hongye Wang, Yang Liu
Summary: The study developed a sensitive electrochemical biosensor for the detection of exosomes and their surface proteins, showing high selectivity and sensitivity. Through dual amplification effect, the electrochemical detection of exosomes was realized, demonstrating great potential for clinical diagnostics as an important tool.
Article
Chemistry, Multidisciplinary
Shoichi Nishitani, Tiffany Tran, Andrew Puglise, Sounghyun Yang, Markita P. Landry
Summary: This study presents the development of near-infrared fluorescent single-walled carbon nanotube (SWCNT) based nanosensors for glucose imaging. The authors find that the fluorescence modulation of GOx-SWCNT is not associated with the enzymatic activity but rather triggered by the substrate-enzyme binding. Leveraging this unique mechanism, the authors developed catalytically inactive nanosensors that enable glucose imaging in mouse brain slices.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)