Article
Chemistry, Physical
Eimantas Ramonas, Atefeh Shafaat, Marius Dagys, Tautgirdas Ruzgas, Dalius Ratautas
Summary: This study investigated the catalytic properties of citrate-capped gold nanoparticles and gold nanoparticle-protein conjugates, showing that gold nanoparticles form stable conjugates with proteins but do not increase enzyme activity. Under certain conditions, gold nanoparticles can mimic enzymatic reactions, emphasizing the need for specific measurements to differentiate between enzyme and gold nanoparticle-catalyzed reactions.
JOURNAL OF CATALYSIS
(2021)
Article
Chemistry, Analytical
Gilberto Henao-Pabon, Ning Gao, K. Sudhakara Prasad, XiuJun Li
Summary: A disposable paper-based glucose biosensor with direct electron transfer of glucose oxidase was developed using simple covalent immobilization. It exhibited high electron transfer rate and good affinity for glucose oxidase, while maintaining enzymatic activities. This low-cost glucose biosensor achieved a wide glucose detection range and remarkable selectivity, making it suitable for monitoring different stages of diabetes.
Article
Chemistry, Physical
Minying Wu, Qian Zhang, Yuanyuan Fang, Chao Deng, Fangzhou Zhou, Yi Zhang, Xingdong Wang, Yi Tang, Yajun Wang
Summary: Two-dimensional nanoreactors with cascade catalytic activity for glucose oxidation and hydrogen peroxide decomposition were prepared by immobilizing GOx on Ti3C2 MXene nanosheets. The GOx-conjugated Ti3C2-PLL nanosheets exhibited excellent enzymatic activities and were further deposited on glassy carbon electrode to construct a high-performance biosensor with a low glucose detection limit.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Multidisciplinary Sciences
Bongjin Jeong, Rashida Akter, Jeonghyun Oh, Dong-Gi Lee, Chang-Geun Ahn, Jong-Soon Choi, Md. Aminur Rahman
Summary: A novel and facile biosensor for post-mortem interval (PMI) detection was developed using a double-label strategy to detect the glyceraldehyde 3-phosphate dehydrogenase (GAPDH) biomarker. The sensor showed high sensitivity and selectivity for GAPDH, making it a promising tool for PMI determination in real samples.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Analytical
Yang-Yang Hou, Jing Xu, Fu-Ting Wang, Zhong Dong, Xuecai Tan, Ke-Jing Huang, Jia-Qiang Li, Chun-Yang Zuo, Si-Qi Zhang
Summary: A novel self-powered biosensing platform was developed for detecting miRNA, utilizing an EBFC-based biosensor with a matching capacitor. By improving the EBFC performance with catalytic hairpin assembly and hybrid chain reaction, along with using a matching capacitor for signal amplification, the sensitivity was significantly increased.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Umut Bulut, Vuslat Oyku Sayin, Yasin Altin, Sevki Can Cevher, Ali Cirpan, Ayse Celik Bedeloglu, Saniye Soylemez
Summary: A specific and stable biosensor for glucose was designed using a flexible, modified electrode with a carbon nanofiber (CNF) and a novel conjugated polymer. The biosensor exhibited a linear response to glucose within a concentration range of 20 mu M to 500 mu M, with a detection limit of 8.5 mu M. It also demonstrated good sensing ability for glucose in beverages.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Rafael Leonardo Cruz Gomes da Silva, Shiv K. Sharma, Suraj Paudyal, Keenan J. Mintz, Roger M. Leblanc, Luciano Caseli
Summary: This work explores the physicochemical properties of mixed stearic acid (HSt)/phenylalanine dehydrogenase enzyme (PheDH) Langmuir films and their immobilization onto solid supports as Langmuir-Blodgett films. The hydrophobic interactions between the enzyme and HSt were found to tune the secondary structure of PheDH. The stability of the mixed floating monolayers allowed their successful transfer to solid supports and formation of LB films, which is crucial for creating optical and electrochemical sensors for phenylalanine with controlled molecular architecture.
Article
Biochemistry & Molecular Biology
Siyuan Liu, Jingxing Liu, Zefen Wang, Zhiqi Wu, Yiliang Wei, Pengru Liu, Xiongdiao Lan, Yexin Liao, Ping Lan
Summary: A novel immobilized glucose oxidase (GOx) based on amorphous Zn-MOFs (DA-PEG-DA/GOx@aZIF-7/PDA) was developed, which showed enhanced stability, excellent reusability, and promising potential for glucose detection. The in situ embedding strategy provided not only a preparation strategy of immobilized enzyme with high activity, high stability, and low enzyme leakage rate, but also a more comprehensive understanding of the formation of immobilized enzymes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Physical
Ji Hyun Yang, Hyeong Ryeol Kim, Ja Hyun Lee, Joon-Hyung Jin, Hee Uk Lee, Seung Wook Kim
Summary: The study aimed to enhance power output by optimizing electrical communication for GOx on a composite surface and found that immobilized GOx at a concentration of 40:80 mM EDC:NHS exhibited the highest activity with a power density of 2.24 mWcm(-2) under optimal conditions.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Chemistry, Analytical
Laura Sakalauskiene, Anton Popov, Asta Kausaite-Minkstimiene, Arunas Ramanavicius, Almira Ramanaviciene
Summary: In this study, electrochemical glucose biosensors based on graphite rod electrode modified with dendritic gold nanostructures and glucose oxidase were developed. Three methods for immobilization of glucose oxidase were compared, and it was found that using GA-GOx-SAM/DGNs/GR electrode provided the highest current response with low detection limit and the same linear dynamic range. The developed biosensors showed good stability and sensitivity.
Article
Chemistry, Physical
Ievgen Kurylo, Sophie Demoustier-Champagne, Christine Dupont-Gillain
Summary: Nanoconfinement plays an important role in modulating the catalytic properties of enzymes. The catalytic activity of enzyme-based nanotubes depends on factors such as pore diameter and the concentration of polyelectrolytes.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Multidisciplinary
Juan M. Devida, Facundo Herrera, M. Antonieta Daza Millone, Feilix G. Requejo, Diego Pallarola
Summary: Graphene oxide is widely used in electrical sensors for monitoring various processes. However, the presence of defects on the surface of the graphene affects its electrical properties. Therefore, it is important to adjust the surface chemistry of graphene oxide for the immobilization of biomolecules while preserving its electrochemical integrity.
Article
Nanoscience & Nanotechnology
Liping Gao, Jin Wen, Zhiyang Huang, Shouri Sheng, Fugang Xu, Guangran Ma, Hongliang Tan
Summary: A pH meter-assisted biosensor based on glucose oxidase (GOx)-conjugated magnetic zeolitic imidazolate framework-8 (mZIF-8) was developed for the on-site evaluation of bacterial contamination. The mZIF-8/GOx conjugate inhibited GOx activity without protein denaturation, but the presence of bacteria caused the release of GOx from the mZIF-8 surface, resulting in the recovery of GOx activity and the generation of an amplified pH signal. The biosensor exhibited enhanced sensitivity and precision, with detection limits of 10 cfu/mL for Escherichia coli and 30 cfu/mL for Staphylococcus aureus.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Anahita Izadyar, My Ni Van, Kayleigh Amber Rodriguez, Ilwoo Seok, Elizabeth E. Hood
Summary: By utilizing recombinant enzymes derived from corn, researchers developed a novel biosensor for glucose detection that offers fast, accurate, and cost-effective measurements. The biosensor demonstrated excellent amperometric response to detect glucose over a wide range, with high reproducibility and selectivity in experimental solutions.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Analytical
Oleh Smutok, Evgeny Katz
Summary: This review gives an overview of different biosensors, focusing on electrochemical analytical devices. It briefly explains the general approaches, construction, and performance of various biosensors. The article discusses how all the components of biosensors are brought together for analytical work, including the immobilization of biomolecular components and their integration with electronic devices. The review mainly covers general concepts of biosensing processes rather than specific modern achievements in the field.
Article
Biophysics
Venkata Suresh Vajrala, Fadhila Sekli Belaidi, Gabriel Lemercier, Dodzi Zigah, Michel Rigoulet, Anne Devin, Neso Sojic, Pierre Temple-Boyer, Jerome Launay, Stephane Arbault
BIOSENSORS & BIOELECTRONICS
(2019)
Article
Chemistry, Multidisciplinary
Cyril Poriel, Frederic Barriere, Joelle Rault-Berthelot, Damien Thirion
CHEMISTRY-A EUROPEAN JOURNAL
(2019)
Article
Chemistry, Multidisciplinary
Franck Camerel, Gregory Albert, Frederic Barriere, Corinne Lagrost, Marc Fourmigue, Olivier Jeannin
CHEMISTRY-A EUROPEAN JOURNAL
(2019)
Article
Chemistry, Inorganic & Nuclear
Antoine Vacher, Yann Le Gal, Thierry Roisnel, Vincent Dorcet, Thomas Devic, Frederic Barriere, Dominique Lorcy
Article
Chemistry, Analytical
Estelle Lebegue, Frederic Barriere, Allen J. Bard
ANALYTICAL CHEMISTRY
(2020)
Article
Nanoscience & Nanotechnology
Malinee Niamlaem, Oranit Phuakkong, Patrick Garrigue, Bertrand Goudeau, Valerie Ravaine, Alexander Kuhn, Chompunuch Warakulwit, Dodzi Zigah
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Biophysics
T. Flinois, E. Lebegue, A. Zebda, J-P Alcaraz, D. K. Martin, F. Barriere
COLLOIDS AND SURFACES B-BIOINTERFACES
(2020)
Article
Chemistry, Inorganic & Nuclear
Hadi Hachem, HengBo Cui, Reizo Kato, Olivier Jeannin, Frederic Barriere, Marc Fourmigue, Dominique Lorcy
Summary: Two selenated analogues of a sulfur-containing nickel complex have been synthesized, showing different solid-state structures and electrical properties. One exhibits a large semiconducting gap and low conductivity, while the other has a conventional layered structure with a smaller HOMO-LUMO gap.
INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Alessandro Iannaci, Adam Myles, Timothe Philippon, Frederic Barriere, Eoin M. Scanlan, Paula E. Colavita
Summary: Surface modification of electrodes with glycans was explored as a strategy to modulate the development of electrocatalytic biofilms in microbial fuel cell applications. The presence of different types of glycans on electrodes significantly impacted the performance of microbial fuel cell devices, with lactosides inhibiting biofilm development and mannosides promoting biofilm adhesion. This study demonstrates the potential of leveraging specific glycan-mediated bioaffinity interactions to direct the development of biotic electrocatalysts in bioelectrochemical systems.
Article
Biochemistry & Molecular Biology
Alessandro Iannaci, Swapnil Ingle, Carlota Dominguez, Mariangela Longhi, Odile Merdrignac-Conanec, Soraya Ababou-Girard, Frederic Barriere, Paula E. Colavita
Summary: Nanostructured electrocatalysts using Fe/N-carbon were found to have better performance and cost-effectiveness compared to Pt/C cathodes in microbial fuel cells. The optimized nanocarbon scaffold resulted in a 25% increase in maximum power densities at a fraction of the material costs.
BIOELECTROCHEMISTRY
(2021)
Article
Electrochemistry
Tobias F. Burton, Yachao Zhu, Lea Droguet, Rossukon Jommongkol, Dodzi Zigah, Alexis Grimaud, Jean-Marie Tarascon, Olivier Fontaine
Summary: This article introduces a novel water-in-salt electrolyte (WISE) with reduced free water content and solves the issues of unstable solid electrolyte interphase (SEI) and salt precipitation/dissolution by adding poly(ethylene glycol) diglycidyl ether (PDE).
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Yannick Dufil, Marc Dietrich, Dodzi Zigah, Frederic Favier, Said Sadki, Pascal Gentile, Olivier Fontaine
Summary: This study introduces scanning electrochemical microscopy (SECM) as a new technique for in situ characterization and acceleration of degradation processes of conducting polymers, aiming to study the conjugated/conducting polymer-based nanostructured electrodes used for micro-electrochemical energy storage (MEES).
Article
Chemistry, Multidisciplinary
Haia Kharraz, Hadi Hachem, Yann Le Gal, Thierry Roisnel, Olivier Jeannin, Frederic Barriere, Thierry Guizouarn, Dominique Lorcy
Summary: Tetrathiafulvalenes (TTFs) were functionalized with groups that enhance non-covalent intermolecular interactions. The study involved designing appropriate precursors and assessing the electronic effect of the substituents on the overall donating ability of the TTFs. Charge transfer salts were prepared and their crystal structures were analyzed to understand the stacking mode and non-covalent interactions in the solid state.
Article
Electrochemistry
Estelle Lebegue, Nazua L. Costa, Ricardo O. Louro, Frederic Barriere
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2020)
Article
Chemistry, Multidisciplinary
Hadi Hachem, Olivier Jeannin, Marc Fourmigue, Frederic Barriere, Dominique Lorcy