Review
Medicine, General & Internal
Randall T. Espinoza, Charles H. Kellner
Summary: Update on Electroconvulsive Therapy (ECT): ECT is effective for several disorders, notably severe or treatment-resistant depression, showing rapid response. However, stigma hampers its usage. The mechanism remains unknown, but a seizure is necessary for efficacy. ECT prominently affects memory, albeit transiently.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Psychiatry
A. Coman
Summary: This study explores the issue of information provision about electroconvulsive treatment (ECT) and finds that the majority of participants experienced an education deficit throughout the treatment period, with oral information being the primary source and a lack of follow-up services. Therefore, it is important to strengthen patient education and autonomy, provide more varied and accurate information, and reduce social stigma.
Review
Biochemistry & Molecular Biology
Milagros Rojas, Daniela Ariza, Angel Ortega, Manuel E. Riano-Garzon, Mervin Chavez-Castillo, Jose Luis Perez, Lorena Cudris-Torres, Maria Judith Bautista, Oscar Medina-Ortiz, Joselyn Rojas-Quintero, Valmore Bermudez
Summary: This article provides a review of the neurobiological, endocrine, and immune mechanisms involved in electroconvulsive therapy (ECT) and discusses its clinical efficacy in various psychiatric disorders. The review suggests that ECT induces neurobiological changes, endocrine and immune alterations which contribute to its therapeutic effects. The study also highlights the expanding use of ECT in treating other conditions such as Parkinson's disease psychosis, malignant neuroleptic syndrome, post-traumatic stress disorder, and obsessive-compulsive disorder.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Psychology, Multidisciplinary
Hui Shi, Honglin Ren, Ying Tian, Zhe Chen, Cuiping Xu, Lu Lu, Xiaoyu Ma, Xiaoyan Li, Wenming Chen, Tong Guo, Cuizhen Fan, Wen Gao
Summary: The study investigated the prevalence of depression or anxiety in patients with multiple myeloma during maintenance treatment in China. Results showed that despite being in clinical remission, depressive mood problems in patients with MM remain prominent. Clinicians should enhance mood assessment and management in patients with concomitant pain.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Medicine, General & Internal
Johanne Eliacin, Jessica Carter, Emily Bass, Mindy Flanagan, Michelle P. Salyers, Alan McGuire
Summary: The study explores the understanding and practice of shared decision-making (SDM) in Veterans Health Administration (VHA) inpatient mental healthcare units. The results suggest that the implementation of SDM is feasible in these units. However, there is a gap between understanding and practice, highlighting the need for ongoing implementation support for SDM. The study also emphasizes the importance of patient autonomy and creating a supporting and empowering environment for SDM.
Article
Medicine, General & Internal
Markku Lahteenvuo, Ari Ahola-Olli, Kimmo Suokas, Minna Holm, Zuzanna Misiewicz, Tuomas Jukuri, Teemu Maennynsalo, Asko Wegelius, Willehard Haaki, Risto Kajanne, Aija Kyttala, Annamari Tuulio-Henriksson, Kaisla Lahdensuo, Katja Hakkinen, Jarmo Hietala, Tiina Paunio, Jussi Niemi-Pynttari, Tuula Kieseppa, Juha Veijola, Jouko Lonnqvist, Erkki Isometsa, Olli Kampman, Jari Tiihonen, Steven Hyman, Benjamin Neale, Mark Daly, Jaana Suvisaari, Aarno Palotie
Summary: The purpose of this study is to establish a large Finnish collection of psychosis cases, including diverse populations from Asia, Latin America, and Africa, in addition to known population isolates like Finland. A total of 10,474 individuals aged 18 years or older were recruited and genotyped. The future plans of this study include investigating the effects of common variants, rare variants, and copy number variations on the severity of psychotic illness, as well as tracking the longitudinal course of illness based on nationwide register data.
Review
Medicine, General & Internal
Stevan Nikolin, Kieran Owens, Rohan Francis-Taylor, Anna Chaimani, Donel M. Martin, Michael Bull, Harold A. Sackeim, Declan M. McLoughlin, Pascal Sienaert, Charles H. Kellner, Colleen Loo
Summary: This study aims to compare the efficacy, cognitive side effects and acceptability of different types of electroconvulsive therapy for major depressive episodes, using a network meta-analysis approach.
Article
Health Care Sciences & Services
Hideyuki Iwanaga, Takefumi Ueno, Naoya Oribe, Manabu Hashimoto, Jun Nishimura, Naho Nakayama, Nami Haraguchi, Hiroshi Tateishi, Yutaka Kunitake, Yoshito Mizoguchi, Akira Monji
Summary: The study indicates that an increase in alpha-band spectral power after acute ECT is associated with improvement in patients' emotional and mental states. Therefore, the increase in spectral power of the alpha band can serve as an objective indicator of the treatment effect of ECT.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Medicine, General & Internal
Rashmi Patel, Jessica Irving, Aimee Brinn, Matthew Taylor, Hitesh Shetty, Megan Pritchard, Robert Stewart, Paolo Fusar-Poli, Philip McGuire
Summary: This study investigated the associations of bipolar depression and depressive symptoms with clinical outcomes. The results showed that the presence of bipolar or overlapping symptoms in patients with unipolar depression is associated with worse clinical outcomes. Symptom-based approaches are more effective in predicting subsequent clinical outcomes than psychiatric diagnosis alone.
Article
Medicine, General & Internal
Dara K. Y. Leung, Kayla K. Y. Wong, Aimee Spector, Gloria H. Y. Wong
Summary: The study found that Chinese carers adopt strategies such as maintaining the personhood of the person with dementia, responding positively to BPSD, explanation and bargaining, responding negatively to BPSD, controlling upsetting thoughts, and seeking respite care to manage BPSD. They value warm and supportive family relationships, identify and minimize triggers, but some may struggle with care tasks. Changing attitudes, seeking social and emotional support, and practicing self-care were described to manage carers' distress.
Article
Medicine, General & Internal
Emma Millard, Emma Medlicott, Jessica Cardona, Stefan Priebe, Catherine Carr
Summary: The survey found that approximately 60% of participants were interested in taking part in group arts therapies, with music therapy being the most popular choice among mental health patients and art therapy preferred by the general population. Past experience with arts therapies was a key predictor of preference for a particular modality. Participants cited expectations of enjoyment, helpfulness, feeling capable, impact on mood, and social interaction as the main reasons for choosing a specific arts therapy form.
Article
Psychology, Clinical
Chittaranjan Andrade
Summary: Patients with major mental illness have a high risk of relapse if they discontinue pharmacotherapy or ECT. Older age and presence of psychotic symptoms predict lower relapse risk, while bipolar II diagnosis and more previous depressive episodes predict higher relapse risk. Abrupt discontinuation of maintenance ECT can lead to relapse within a short time frame, especially in patients with psychosis or history of multiple ECT courses.
JOURNAL OF CLINICAL PSYCHIATRY
(2021)
Review
Psychology, Developmental
Santiago Castaneda-Ramirez, Timothy D. Becker, Adriana Bruges-Boude, Charles Kellner, Timothy R. Rice
Summary: ECT has been shown to be a safe and effective treatment for mood disorders in child and adolescent populations, particularly in severe and treatment-refractory cases. However, further controlled studies are needed to confirm its efficacy and long-term effects.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Medicine, General & Internal
Milena Falcaro, David Osborn, Joseph Hayes, Gary Coyle, Lisa Couperthwaite, Scott Weich, Kate R. Walters
Summary: The study investigated the delivery of smoking cessation interventions in primary care for smokers with depression or severe mental illness (SMI) compared to those without. It found that although smokers with SMI received more smoking cessation advice initially, the gap reduced in recent years. Despite an increase in smoking cessation advice, there were no corresponding increases in quit attempts or changes in smoking status.
Article
Health Care Sciences & Services
Sevdalina Kandilarova, Drozdstoy St. Stoyanov, Rositsa Paunova, Anna Todeva-Radneva, Katrin Aryutova, Michael Maes
Summary: This study investigated the differences in connectomes between psychiatric patients and healthy controls, revealing that dysfunction in the self-regulation of the salience network may underpin major mental disorders. Key connectome features differentiate mood disorders from schizophrenia, and can serve as potential imaging biomarkers.
JOURNAL OF PERSONALIZED MEDICINE
(2021)