期刊
JOURNAL OF ECT
卷 28, 期 3, 页码 190-193出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/YCT.0b013e3182542649
关键词
brain lateralization; brain stimulation; brain imaging; neurological soft signs; mind-brain relationship
This case report describes the successful response to electroconvulsive therapy (ECT) in a patient with an unusual presentation of catatonia, whose onset occurred in the context of an extremely severe form of refractory obsessive-compulsive disorder (OCD). We correlated the clinical improvement in catatonic and OCD symptoms with specific changes in brain function as shown by regional cerebral blood flow scans, neurological soft signs examination, and neuropsychological testing. All assessments were conducted before and after the ECT course. The results strongly suggest that a right hemisphere dysfunction was the neural correlate of our patient's symptoms, and that ECT, by reverting this abnormality, may serve as an effective therapeutic approach for refractory catatonic OCD.
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