Article
Clinical Neurology
Santiago Madero, Gerard Anmella, Maria Sague-Vilavella, Maria Teresa Pons, Anna Gimenez, Andrea Murru, Marta Gomez-Ramiro, Joaquin Gil-Badenes, Jose Rios, Miquel Bioque, Eduard Vieta, Antonio Benabarre
Summary: This study aimed to investigate the real-life effectiveness of maintenance electroconvulsive therapy(mECT) in bipolar disorder(BD). The results showed that mECT can effectively reduce the number and duration of psychiatric hospitalizations in BD patients, supporting its effectiveness in the treatment of BD.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Clinical Neurology
Santiago Madero, Gerard Anmella, Maria Sague-Vilavella, Maria Teresa Pons, Anna Gimenez, Andrea Murru, Marta Gomez-Ramiro, Joaquin Gil-Badenes, Jose Rios, Miquel Bioque, Eduard Vieta, Antonio Benabarre
Summary: This study aimed to investigate the effectiveness of maintenance electroconvulsive therapy (mECT) in treating bipolar disorder (BD). The results showed that mECT had a 62.2% effectiveness in preventing psychiatric hospitalizations and significantly reduced the number of hospitalization days and admissions for BD patients.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Medicine, General & Internal
Sergey Mosolov, Christoph Born, Heinz Grunze
Summary: This study examined the clinical experience of using ECT in patients with rapid cycling bipolar disorder and unstable mixed states. The results showed that ECT was very effective for about 40% of patients, helping them achieve and maintain remission. Additionally, ECT significantly reduced the duration of affective episodes in rapid and ultra-rapid cycling bipolar patients.
MEDICINA-LITHUANIA
(2021)
Review
Psychiatry
Jian Zhang, Guojun Wang, Xi Yang, Keming Gao
Summary: A meta-analysis compared the efficacy and safety of ECT combination with medication versus medication alone in treating acute mania. ECT-combo was found to outperform Med-alone in reducing manic symptoms, but also had increased memory impairment. Larger studies are needed to further confirm these findings due to high heterogeneity in the included studies.
PSYCHIATRY RESEARCH
(2021)
Review
Psychology, Clinical
Anil K. Bachu, Vijaya Padma Kotapati, Tejasvi Kainth, Rikinkumar Patel, Nagy A. Youssef, Rajesh R. Tampi
Summary: This study systematically reviewed the literature on the use of electroconvulsive therapy (ECT) in patients with dementia/major NCD presenting with behavioral symptoms. The results showed that ECT can effectively alleviate behavioral symptoms in these patients, but sometimes adverse events may occur.
INTERNATIONAL PSYCHOGERIATRICS
(2023)
Review
Clinical Neurology
L. Roosen, P. Sienaert
Summary: This paper provides an overview of evidence-based treatment options for rapid cycling in bipolar disorder, highlighting medications such as aripiprazole, olanzapine, quetiapine, valproate, and lamotrigine. However, evidence regarding the treatment of rapid cycling remains scarce, indicating the need for future research to further validate the efficacy of these treatment methods.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Psychiatry
Gao Zhihan, Sun Fengli, Lv Wangqiang, Shen Dong, Jin Weidong
Summary: The combination of lithium and lamotrigine has shown to be effective in improving mental symptoms and increasing response rates in patients with rapid-cycling bipolar disorder.
FRONTIERS IN PSYCHIATRY
(2022)
Review
Psychiatry
Subho Chakrabarti, Amal J. Jolly, Pranshu Singh, Nidhi Yadhav
Summary: Rapid-cycling bipolar disorder (RCBD) is a common subtype of bipolar disorder characterized by greater severity and disability, with limited efficacy of conventional pharmacotherapy. There is a lack of robust evidence regarding optimal treatment strategies for RCBD, especially nonpharmacological interventions. However, preliminary studies suggest that adjunctive electroconvulsive therapy and chronotherapeutic treatments may be beneficial for RCBD management.
WORLD JOURNAL OF PSYCHIATRY
(2023)
Article
Psychiatry
Erhan Kavakbasi, Franziska Rodner, Lavanja Nimalavachchlan, Kathrin Schwarte, Christiane Schettler, Linda M. Bonnekoh, Nils Opel, Anne-Christin Peine, Bernhard T. Baune, Christa Hohoff
Summary: This case study reports on the use of electroconvulsive therapy (ECT) in a middle-aged man with multiple sclerosis (MS) and treatment-resistant severe bipolar depression. The results show that ECT was well-tolerated and did not lead to neurological deterioration or new neurological symptoms. Partial response was observed in terms of symptom improvement, and the concentration of inflammation and neurodegeneration biomarkers was low.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychiatry
Giulio E. Brancati, Beniamino Tripodi, Martina Novi, Margherita Barbuti, Pierpaolo Medda, Giulio Perugi
Summary: The study found that a history of multiple drug treatments during the current episode of bipolar depression may be associated with a greater resistance to all types of therapies, including ECT.
PSYCHIATRY RESEARCH
(2021)
Article
Neurosciences
Ying Lu, Yu Tian, Yu Gan, Yixiao Fu, Qibin Chen, Lei Zou, Bangshu Zhao, Yu Yan, Shudong Liu, Xiaolu Chen, Xiao Li
Summary: This study evaluates the efficacy and tolerability of electroconvulsive therapy (ECT) in psychiatric patients with arachnoid cysts. The results show that ECT is an effective and tolerable therapy for these patients.
Article
Clinical Neurology
Linda Steinholtz, Johan Reutfors, Lena Brandt, Pia Nordanskog, Elin Thornblom, Jonas Persson, Robert Boden
Summary: Response rates to electroconvulsive therapy in depression may be lower in patients with concurrent personality or anxiety disorders, but the majority of patients still respond positively. The impact of comorbidity decreases with higher age and severity of depressive episode; subjective ratings of memory impairment do not differ between patients with and without comorbidity.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Psychiatry
Alby Elias, Naveen Thomas, Harold A. Sackeim
Summary: While electroconvulsive therapy (ECT) is no longer the first-line treatment for mania, recent research has shown promising results in its use, including the adoption of ultrabrief ECT, combination with pharmacological agents, and use as a maintenance strategy. Technical parameters, such as treatment frequency, electrode placements, and pulse width, play a critical role in its efficacy.
AMERICAN JOURNAL OF PSYCHIATRY
(2021)
Article
Health Care Sciences & Services
Claudia Pisanu, Erika Vitali, Anna Meloni, Donatella Congiu, Giovanni Severino, Raffaella Ardau, Caterina Chillotti, Luigi Trabucchi, Marco Bortolomasi, Massimo Gennarelli, Alessandra Minelli, Alessio Squassina
Summary: Psychiatric disorders may exhibit premature cell senescence, but the relationship between leukocyte telomere length (LTL) and response to electroconvulsive therapy (ECT) is inconclusive. LTL was found to be shorter in patients with treatment-resistant major depressive disorder (MDD) and bipolar disorder (BD) compared to controls, but baseline LTL was not predictive of ECT response. No significant overlap between genetic variants associated with LTL and ECT response was observed.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Clinical Neurology
Kannapas Kittayarak, Pichai Ittasakul
Summary: The practice of electroconvulsive therapy (ECT) in Thailand has seen significant development over the past two decades, with the majority of patients now being treated with modified ECT. The use of pre-treatment investigations, devices providing brief pulses, unilateral electrode placement, and monitoring of treatment parameters has also become more widespread to enhance treatment efficacy and minimize side effects. However, there are still areas for improvement, such as promoting ECT education among psychiatrists and psychiatry residents.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2022)