Article
Agronomy
Jinyu Hu, Buli Fu, Jinjin Liang, Rong Zhang, Xuegao Wei, Jing Yang, Qimei Tan, Hu Xue, Peipan Gong, Shaonan Liu, Mingjiao Huang, Tianhua Du, Cheng Yin, Chao He, Yao Ji, Chao Wang, Chengjia Zhang, He Du, Qi Su, Xin Yang, Youjun Zhang
Summary: The study found that the whitefly has developed resistance to neonicotinoid insecticides, and this resistance is closely related to the overexpression of the P450 gene CYP4CS5. Knockdown of CYP4CS5 through RNA interference increased mortality in both the resistant and susceptible populations when treated with neonicotinoids, but the opposite result was obtained when using a transgenic fruit fly expressing CYP4CS5. Additionally, the resistant whitefly exhibited a longer development time, shorter longevity, and reduced fecundity compared to the susceptible, indicating fitness costs associated with resistance.
PEST MANAGEMENT SCIENCE
(2023)
Article
Agronomy
Shuai Wu, Lang Yang, Minrong He, Fujin Xia, Yu Shi, Hongsong Chen, Xun Liao, Rongyu Li
Summary: The brown planthopper, a major rice pest in Asia, shows moderate resistance against the widely used insecticide acetamiprid. The resistance is inherited as autosomal and incompletely dominant, controlled by multiple genes. The resistant strain has lower fitness but shorter nymph duration.
Article
Microbiology
Fredrika Rajer, Linus Sandegren
Summary: Multiresistance plasmids have evolutionary advantage in antibiotic treatment environments and impose fitness costs on bacteria. This study investigates the contribution of plasmid-borne resistance genes to bacterial fitness and finds that particular resistance genes are responsible for the cost of the plasmid.
Article
Microbiology
Fredrika Rajer, Linus Sandegren
Summary: Multiresistance plasmids provide bacterial cells with protection against multiple antibiotics, but can also reduce the fitness of bacterial cells. Some resistance genes carried by plasmids incur costs on bacterial cells, while others are cost-free.
Article
Biochemistry & Molecular Biology
Hannah Prensky, Angela Gomez-Simmonds, Anne-Catrin Uhlemann, Allison J. Lopatkin
Summary: The process of plasmid acquisition during conjugation results in immediate but transient metabolic perturbation. This study found that newly acquired transconjugants exhibit slower growth and prolonged lag times compared to cells that have been replicating for several generations, indicating the presence of a plasmid acquisition cost. The short-term effects of plasmid acquisition have been shown to play a critical role in both short- and long-term plasmid prevalence, particularly in microbiomes with high plasmid/strain diversity.
MOLECULAR SYSTEMS BIOLOGY
(2021)
Article
Multidisciplinary Sciences
David Helekal, Matt Keeling, Yonatan H. Grad, Xavier Didelot
Summary: Increasing levels of antibiotic resistance pose a major threat to public health. Understanding the costs and benefits of resistance can lead to better use of antibiotics and prevent the spread of resistance.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2023)
Article
Entomology
Lang Liu, Suji Wang, Junfeng Zuo, Xiaohe Zhang, Xiong Peng, Kang Wang, Maohua Chen
Summary: Rhopalosiphum padi has developed extremely high resistance to the pyrethroid insecticide bifenthrin, with significant cross-resistance to other insecticides. The resistance is likely attributed to the presence of the P450 enzyme and a super-kdr mutation in the voltage-gated sodium channel.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2023)
Article
Agronomy
Dengke Hua, Xiaoyu Li, Jiangjiang Yuan, Min Tao, Kun Zhang, Xiaobin Zheng, Yanran Wan, Lianyou Gui, Youjun Zhang, Qingjun Wu
Summary: This study compared the reproductive capacities, ovary development, and vitellogenin (Vg) gene expression in spinosad-susceptible and -resistant western flower thrips to investigate the reason for the fitness cost in spinosad resistance. The results showed that the spinosad-resistant strain exhibited a decrease in fecundity and shortened ovariole length compared to the susceptible strain. The downregulated expression of Vg was found to contribute to these phenotypic changes and the fitness cost.
PEST MANAGEMENT SCIENCE
(2023)
Article
Agronomy
Mamuna Ijaz, Sarfraz A. Shad
Summary: The study showed that spirotetramat resistance significantly affects the survival and reproductive rate of the Dusky cotton bug population.
PEST MANAGEMENT SCIENCE
(2022)
Article
Agronomy
Bin Zeng, Ya-Ting Liu, Wen-Jing Zhang, Ze-Rui Feng, Shun-Fan Wu, Cong-Fen Gao
Summary: Chinese field populations of Laodelphax striatellus developed high-level buprofezin resistance within the first four years. The resistance was stable for about ten years and persisted even when buprofezin selection pressure was absent. Low-level resistance to several other insecticides was also detected, while nitenpyram and triflumezopyrim showed no resistance.
PEST MANAGEMENT SCIENCE
(2022)
Article
Microbiology
Pedro Dorado-Morales, M. Pilar Garcillan-Barcia, Inigo Lasa, Cristina Solano
Summary: Plasmids play a major role in the spread of antibiotic resistance genes among bacterial strains. This study demonstrates that the initial fitness cost of plasmids in Staphylococcus aureus can be alleviated over time through plasmid rearrangements mediated by insertion sequences, leading to the loss of antimicrobial resistance genes. The results suggest the potential benefits of reducing antibiotic use in both animal and clinical settings to prevent the spread of clinical multidrug resistance plasmids.
Article
Plant Sciences
Helen M. Cockerton, Shiv S. Kaundun, Lieselot Nguyen, Sarah Jane Hutchings, Richard P. Dale, Anushka Howell, Paul Neve
Summary: The study reveals a positive correlation between glyphosate resistance level and EPSPS gene copy number, identifying gene amplification as the resistance mechanism. Glyphosate-resistant A. tuberculatus plants exhibit lower competitive responses and a growth trade-off associated with gene amplification mechanism under intra-phenotypic competition.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Microbiology
Antoine G. Abou Fayad, Louis-Patrick Haraoui, Ahmad Sleiman, Mohamad Jaafar, Abdulaziz Zorgani, Ghassan M. Matar, Paul G. Higgins
Summary: The molecular epidemiology of carbapenem-resistant Acinetobacter baumannii isolates from Libya was investigated, revealing interhospital transmission clusters associated with international clones IC1, IC2, and IC7. Carbapenem resistance was linked to specific genes, with some isolates showing a fitness advantage compared to a reference strain.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Agronomy
Kaixin Li, Jiantao Liu, Ziqiong Geng, Wei Xu, Zhuang Zhang, Dong Chu, Lei Guo
Summary: This study identified a highly resistant Bemisia tabaci population to dinotefuran, a new neonicotinoid insecticide. The resistance was found to be polygenic and incompletely recessive. The study revealed the involvement of P450 enzymes, particularly the CYP6DW5 gene, in the resistance mechanism. This information is important for resistance management in B. tabaci.
PEST MANAGEMENT SCIENCE
(2023)
Article
Environmental Sciences
Shabana Wazir, Sarfraz Ali Shad
Summary: Pesticides are widely used in agriculture to control pests, diseases, and weeds, but their overuse and misuse have led to resistance issues, environmental contamination, and threats to human health. This study on a cotton dusky bug population exposed to fipronil showed significant resistance development, with recommendations for strategies like proper use, rotation, and high-dose application to mitigate resistance and negative impacts.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)