DNA-mediated cooperativity facilitates the co-selection of cryptic enhancer sequences by SOX2 and PAX6 transcription factors

The grammar of transcriptional regulation

(2014) Shira Weingarten-Gabbay et al.   HUMAN GENETICS

Single Molecule Visualization and Characterization of Sox2–Pax6 Complex Formation on a Regulatory DNA Element Using a DNA Origami Frame

(2014) Seigi Yamamoto et al.   NANO LETTERS

An atlas of active enhancers across human cell types and tissues

(2014) Robin Andersson et al.   NATURE

In pursuit of design principles of regulatory sequences

(2014) Michal Levo et al.   NATURE REVIEWS GENETICS

Structural Basis for the SOX-Dependent Genomic Redistribution of OCT4 in Stem Cell Differentiation

(2014) Felipe Merino et al.   STRUCTURE

Absence of a simple code: how transcription factors read the genome

(2014) Matthew Slattery et al.   TRENDS IN BIOCHEMICAL SCIENCES

Subtle Changes in Motif Positioning Cause Tissue-Specific Effects on Robustness of an Enhancer's Activity

(2014) Jelena Erceg et al.   PLoS Genetics

Crystallization and preliminary X-ray diffraction analysis of the Pax9 paired domain bound to a DC5 enhancer DNA element

(2014) Kamesh Narasimhan et al.   Acta Crystallographica Section F-Structural Biology Communications

Nano-Analysis of DNA Conformation Changes Induced by Transcription Factor Complex Binding Using Plasmonic Nanodimers

(2013) Hiroyuki Morimura et al.   ACS Nano

Dynamic trans-Acting Factor Colocalization in Human Cells

(2013) Dan Xie et al.   CELL

Functional dissection of the paired domain of Pax6 reveals molecular mechanisms of coordinating neurogenesis and proliferation

(2013) T. Walcher et al.   DEVELOPMENT

The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis

(2013) Shi-Yan Ng et al.   MOLECULAR CELL

A naturally occuring insertion of a single amino acid rewires transcriptional regulation by glucocorticoid receptor isoforms

(2013) M. Thomas-Chollier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox Transcription Factors Require Selective Interactions with Oct4 and Specific Transactivation Functions to Mediate Reprogramming

(2013) Irene Aksoy et al.   STEM CELLS

An expansive human regulatory lexicon encoded in transcription factor footprints

(2012) Shane Neph et al.   NATURE

Deciphering the Sox-Oct partner code by quantitative cooperativity measurements

(2012) Calista K. L. Ng et al.   NUCLEIC ACIDS RESEARCH

Identification of a Polyoxometalate Inhibitor of the DNA Binding Activity of Sox2

(2011) Kamesh Narasimhan et al.   ACS Chemical Biology

The crystal structure of the Sox4 HMG domain–DNA complex suggests a mechanism for positional interdependence in DNA recognition

(2011) Ralf Jauch et al.   BIOCHEMICAL JOURNAL

Cofactor Binding Evokes Latent Differences in DNA Binding Specificity between Hox Proteins

(2011) Matthew Slattery et al.   CELL

Sequentially acting Sox transcription factors in neural lineage development

(2011) M. Bergsland et al.   GENES & DEVELOPMENT

Discovery and assessment of conserved Pax6 target genes and enhancers

(2011) Pedro Coutinho et al.   GENOME RESEARCH

Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

(2011) Dong Wang et al.   NATURE

Jury remains out on simple models of transcription factor specificity

(2011) Quaid Morris et al.   NATURE BIOTECHNOLOGY

Conversion of Sox17 into a Pluripotency Reprogramming Factor by Reengineering Its Association with Oct4 on DNA

(2011) Ralf Jauch et al.   STEM CELLS

Pax6 Is a Human Neuroectoderm Cell Fate Determinant

(2010) Xiaoqing Zhang et al.   Cell Stem Cell

Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-β effectors

(2010) Nithya BabuRajendran et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of the dimeric Oct6 (POU3f1) POU domain bound to palindromic MORE DNA

(2010) Ralf Jauch et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

NovelSOX2mutations and genotype–phenotype correlation in anophthalmia and microphthalmia

(2009) Adele Schneider et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Novel SOX2 partner-factor domain mutation in a four-generation family

(2009) Marija Mihelec et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

(2008) Vikas Chandra et al.   NATURE