Chemical intervention of the NM23-H2 transcriptional programme onc-MYCvia a novel small molecule

Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo

(2014) T J Phesse et al.   CELL DEATH AND DIFFERENTIATION

A Small Molecule That Binds and Inhibits the ETV1 Transcription Factor Oncoprotein

(2014) M. S. Pop et al.   MOLECULAR CANCER THERAPEUTICS

Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition

(2014) Michael V. Gormally et al.   Nature Communications

DNA G-quadruplex binders: a patent review

(2013) Yiyong Yan et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Pro-oncogenic potential ofNM23-H2in hepatocellular carcinoma

(2012) Mi-Jin Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Bcr–Abl dependent post-transcriptional activation of NME2 expression is a specific and common feature of chronic myeloid leukemia

(2012) Sabine Tschiedel et al.   LEUKEMIA & LYMPHOMA

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: A new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene

(2011) Yan Ma et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Impact of planarity of unfused aromatic molecules on G-quadruplex binding: Learning from isaindigotone derivatives

(2011) Jin-Qiang Hou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Bisaryldiketene derivatives: A new class of selective ligands for c-myc G-quadruplex DNA

(2010) Dan Peng et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Quantitative Structure–Activity Relationship Analysis of 4(3H)-Quinazolone Derivatives as Tyrosine Kinase Inhibitors by Multiple Linear Regression

(2010) Vikas Srivastava et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

A complex task? Direct modulation of transcription factors with small molecules

(2010) Angela N Koehler   CURRENT OPINION IN CHEMICAL BIOLOGY

The landscape of somatic copy-number alteration across human cancers

(2010) Rameen Beroukhim et al.   NATURE

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands

(2009) Yan Ma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification and Characterization of Nucleolin as a c-mycG-quadruplex-binding Protein

(2009) Verónica González et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isaindigotone Derivatives: A New Class of Highly Selective Ligands for Telomeric G-Quadruplex DNA

(2009) Jia-Heng Tan et al.   JOURNAL OF MEDICINAL CHEMISTRY

NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1

(2009) T. S. Dexheimer et al.   MOLECULAR CANCER THERAPEUTICS

Genome-Wide Computational and Expression Analyses Reveal G-Quadruplex DNA Motifs as Conservedcis-Regulatory Elements in Human and Related Species

(2008) Anjali Verma et al.   JOURNAL OF MEDICINAL CHEMISTRY

5-N-Methylated Quindoline Derivatives as Telomeric G-Quadruplex Stabilizing Ligands: Effects of 5-NPositive Charge on Quadruplex Binding Affinity and Cell Proliferation

(2008) Yu-Jing Lu et al.   JOURNAL OF MEDICINAL CHEMISTRY