High-throughput data integration of RNA–miRNA–circRNA reveals novel insights into mechanisms of benzo[a]pyrene-induced carcinogenicity

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

(2015) C. Tomasetti et al.   SCIENCE

Mitochondrial Targeting of Cytochrome P450 (CYP) 1B1 and Its Role in Polycyclic Aromatic Hydrocarbon-induced Mitochondrial Dysfunction

(2014) Seema Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance

(2014) Charles Wang et al.   NATURE BIOTECHNOLOGY

Assessing compound carcinogenicityin vitrousing connectivity mapping

(2013) Florian Caiment et al.   CARCINOGENESIS

Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models

(2013) Tatyana Y. Doktorova et al.   CARCINOGENESIS

Benzo[a]pyrene induces oxidative stress and endothelial progenitor cell dysfunction via the activation of the NF-κB pathway

(2013) KANGTING JI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Aryl Hydrocarbon Receptor-Induced Adrenomedullin Mediates Cigarette Smoke Carcinogenicity in Humans and Mice

(2012) S. Portal-Nunez et al.   CANCER RESEARCH

A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo

(2012) C. Magkoufopoulou et al.   CARCINOGENESIS

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

RNA-Seq Provides New Insights in the Transcriptome Responses Induced by the Carcinogen Benzo[a]pyrene

(2012) J. van Delft et al.   TOXICOLOGICAL SCIENCES

MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood

(2012) Paul J Mintz et al.   Molecular Therapy-Nucleic Acids

Benzo(a)pyrene-induced mitochondrial dysfunction and cell death in p53-null Hep3B cells

(2011) Ying Jiang et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Haplotype and isoform specific expression estimation using multi-mapping RNA-seq reads

(2011) Ernest Turro et al.   GENOME BIOLOGY

Moving Forward in Human Cancer Risk Assessment

(2010) Richard S. Paules et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Time Series Analysis of Benzo[A]Pyrene-Induced Transcriptome Changes Suggests That a Network of Transcription Factors Regulates the Effects on Functional Gene Sets

(2010) Joost H. M. van Delft et al.   TOXICOLOGICAL SCIENCES

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Genetic dissection of the miR-17 92 cluster of microRNAs in Myc-induced B-cell lymphomas

(2009) P. Mu et al.   GENES & DEVELOPMENT

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

(2009) Junfang Ji et al.   HEPATOLOGY

Circulating microRNAs, potential biomarkers for drug-induced liver injury

(2009) K. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

PatMaN: rapid alignment of short sequences to large databases

(2008) Kay Prüfer et al.   BIOINFORMATICS

EpCAM and  -Fetoprotein Expression Defines Novel Prognostic Subtypes of Hepatocellular Carcinoma

(2008) T. Yamashita et al.   CANCER RESEARCH

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

Discovering microRNAs from deep sequencing data using miRDeep

(2008) Marc R Friedländer et al.   NATURE BIOTECHNOLOGY

Transforming Environmental Health Protection

(2008) Francis S. Collins et al.   SCIENCE

Emerging fundamental roles for non-coding RNA species in toxicology

(2008) Emma L. Taylor et al.   TOXICOLOGY

Value of Rodent Carcinogenesis Bioassays

(2007) Jerrold M. Ward   TOXICOLOGY AND APPLIED PHARMACOLOGY