The beta hairpin structure within ribosomal protein S5 mediates interplay between domains II and IV and regulates HCV IRES function

Re-analysis of cryoEM data on HCV IRES bound to 40S subunit of human ribosome integrated with recent structural information suggests new contact regions between ribosomal proteins and HCV RNA

(2014) Agnel Praveen Joseph et al.   RNA Biology

Structures of the human and Drosophila 80S ribosome

(2013) Andreas M. Anger et al.   NATURE

Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit

(2013) Yaser Hashem et al.   NATURE

HCV IRES interacts with the 18S rRNA to activate the 40S ribosome for subsequent steps of translation initiation

(2013) A. A. Malygin et al.   NUCLEIC ACIDS RESEARCH

Hepatitis C virus 3′UTR regulates viral translation through direct interactions with the host translation machinery

(2013) Yun Bai et al.   NUCLEIC ACIDS RESEARCH

HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation

(2012) Megan E Filbin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Targeting Ribosome assembly on the HCV RNA using a small RNA molecule

(2012) Prasanna Bhat et al.   RNA Biology

Attenuation of 40S Ribosomal Subunit Abundance Differentially Affects Host and HCV Translation and Suppresses HCV Replication

(2012) Jing-Ying Huang et al.   PLoS Pathogens

ModeRNA: a tool for comparative modeling of RNA 3D structure

(2011) Magdalena Rother et al.   NUCLEIC ACIDS RESEARCH

HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove

(2011) M. E. Filbin et al.   RNA

The HADDOCK web server for data-driven biomolecular docking

(2010) Sjoerd J de Vries et al.   Nature Protocols

The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit

(2010) K. E. Berry et al.   RNA

Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1

(2010) J. Rabl et al.   SCIENCE

Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome

(2009) Rebecca M Voorhees et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Positioning of subdomain IIId and apical loop of domain II of the hepatitis C IRES on the human 40S ribosome

(2009) E. Babaylova et al.   NUCLEIC ACIDS RESEARCH

A one-step PCR-based method for rapid and efficient site-directed fragment deletion, insertion, and substitution mutagenesis

(2008) Dong Qi et al.   JOURNAL OF VIROLOGICAL METHODS

Structure and function of HCV IRES domains

(2008) Peter J. Lukavsky   VIRUS RESEARCH