The PIN domain of EXO1 recognizes poly(ADP-ribose) in DNA damage response

Poly(ADP-ribosyl)ation is recognized by ECT2 during mitosis

(2014) Mo Li et al.   CELL CYCLE

The oligonucleotide/oligosaccharide-binding fold motif is a poly(ADP-ribose)-binding domain that mediates DNA damage response

(2014) F. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Functional Cancer Genomics Screen Identifies a Druggable Synthetic Lethal Interaction between MSH3 and PRKDC

(2014) F. Dietlein et al.   Cancer Discovery

Function of BRCA1 in the DNA Damage Response Is Mediated by ADP-Ribosylation

(2013) Mo Li et al.   CANCER CELL

An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay

(2013) S. Jonas et al.   GENES & DEVELOPMENT

The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response

(2013) M. Li et al.   GENES & DEVELOPMENT

PCNA promotes processive DNA end resection by Exo1

(2013) Xiaoqing Chen et al.   NUCLEIC ACIDS RESEARCH

Recognition of the iso-ADP-ribose moiety in poly(ADP-ribose) by WWE domains suggests a general mechanism for poly(ADP-ribosyl)ation-dependent ubiquitination

(2012) Z. Wang et al.   GENES & DEVELOPMENT

On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1

(2012) X. Luo et al.   GENES & DEVELOPMENT

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

(2012) Bryan A. Gibson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks

(2012) Jana Krietsch et al.   NUCLEIC ACIDS RESEARCH

DNA end resection—Unraveling the tail

(2011) Eleni P. Mimitou et al.   DNA REPAIR

PARP-1 enhances the mismatch-dependence of 5′-directed excision in human mismatch repair in vitro

(2011) Yiyong Liu et al.   DNA REPAIR

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

(2011) A. V. Nimonkar et al.   GENES & DEVELOPMENT

DNA Repair Factor APLF Is a Histone Chaperone

(2011) Pawan Vinod Mehrotra et al.   MOLECULAR CELL

The macro domain protein family: Structure, functions, and their potential therapeutic implications

(2011) Weidong Han et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

(2011) Yue Zhang et al.   NATURE CELL BIOLOGY

Release of Ku and MRN from DNA Ends by Mre11 Nuclease Activity and Ctp1 Is Required for Homologous Recombination Repair of Double-Strand Breaks

(2011) Petra Langerak et al.   PLoS Genetics

Oligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardians

(2010) Rachel Litman Flynn et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks

(2010) Sascha E. Liberti et al.   DNA REPAIR

Mechanism of Holliday junction resolution by the human GEN1 protein

(2010) U. Rass et al.   GENES & DEVELOPMENT

Double-stranded DNA Binding Domain of Poly(ADP-ribose) Polymerase-1 and Molecular Insight into the Regulation of Its Activity

(2010) Orlando Huambachano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mre11–Rad50–Xrs2 and Sae2 promote 5′ strand resection of DNA double-strand breaks

(2010) Matthew L Nicolette et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose)

(2010) Sebastian Eustermann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

(2010) D. M. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response

(2010) G.-Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PIN-domain ribonucleases and the prokaryotic VapBC toxin-antitoxin array

(2010) V. L. Arcus et al.   PROTEIN ENGINEERING DESIGN & SELECTION

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

(2009) Feng Zhang et al.   CURRENT BIOLOGY

Involvement of Nucleotide Excision and Mismatch Repair Mechanisms in Double Strand Break Repair

(2009) Ye Zhang et al.   CURRENT GENOMICS

DNA end resection: Many nucleases make light work

(2009) Eleni P. Mimitou et al.   DNA REPAIR

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks

(2009) Emma Bolderson et al.   NUCLEIC ACIDS RESEARCH

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

(2009) A. J. Gottschalk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poly(ADP-ribose)-Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1

(2009) D. Ahel et al.   SCIENCE

Nucleases and helicases take center stage in homologous recombination

(2009) Eleni P. Mimitou et al.   TRENDS IN BIOCHEMICAL SCIENCES

The P. furiosus Mre11/Rad50 Complex Promotes 5′ Strand Resection at a DNA Double-Strand Break

(2008) Ben B. Hopkins et al.   CELL

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

(2008) S. Gravel et al.   GENES & DEVELOPMENT

Recruitment of mismatch repair proteins to the site of DNA damage in human cells

(2008) Z. Hong et al.   JOURNAL OF CELL SCIENCE

Characterization of a Highly Conserved Binding Site of Mlh1 Required for Exonuclease I-Dependent Mismatch Repair

(2008) C. Dherin et al.   MOLECULAR AND CELLULAR BIOLOGY

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE

Identification of Holliday junction resolvases from humans and yeast

(2008) Stephen C. Y. Ip et al.   NATURE

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

(2008) Ivan Ahel et al.   NATURE

The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases

(2007) Paul et al.   Frontiers in Bioscience-Landmark