Article
Dentistry, Oral Surgery & Medicine
Maria Elisa Galarraga-Vinueza, Karina Obreja, Ausra Ramanauskaite, Ricardo Magini, Amira Begic, Robert Sader, Frank Schwarz
Summary: The study immunohistochemically characterized macrophage polarization at peri-implantitis sites and found that macrophages constituted a significant portion of the inflammatory cellular composition, with a higher expression of M1 phenotype in advanced peri-implantitis cases. This higher M1 expression may play a critical role in disease progression.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
I-Ching Wang, Jim Sugai, Jad Majzoub, Jeffery Johnston, William Giannobile, Hom-Lay Wang
Summary: This study found a weak association between peri-implantitis and CVD, which is supported by the increased expression of local and systemic pro-inflammatory cytokines.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Lorenzo Marini, Cristiano Tomasi, Rodolfo Gianserra, Filippo Graziani, Luca Landi, Mauro Merli, Luigi Nibali, Mario Roccuzzo, Nicola M. Sforza, Maurizio S. Tonetti, Federico Deli, Piero Papi, Bianca Di Murro, Mariana A. Rojas, Andrea Pilloni
Summary: The purpose of this study was to evaluate the reliability and accuracy of assigning case definitions to dental implants according to the 2018 classification. The study found that the reliability and accuracy of the case definitions were mostly moderate.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Tamires Pereira Dutra, Mabelle Freitas Monteiro, Isabela Lima Franca-Grohmann, Renato Correa Viana Casarin, Marcio Zaffalon Casati, Karina Gonzalez Silverio Ruiz, Purnima S. Kumar, Enilson Antonio Sallum
Summary: This study compared individuals with a history of periodontitis to periodontally healthy subjects in terms of immunological and microbiological changes during experimental peri-implant mucositis and gingivitis. The results showed that different microbial shifts contribute to the onset and progression of inflammatory responses around teeth and implants, while the history of periodontal disease plays a role in modulating the immune response.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Himabindu Dukka, Muhammad H. A. Saleh, Andrea Ravida, Henry Greenwell, Hom-Lay Wang
Summary: Bleeding on probing (BOP) is an indispensable diagnostic tool for evaluating periodontal disease, but its role in peri-implant disease is more complex. The confusion in interpretation is due to differences in how BOP originates and is used in implants. A comprehensive bleeding index and other parameters should be used together for diagnosing peri-implant diseases accurately.
JOURNAL OF PERIODONTOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Liat Chaushu, Haim Tal, Anton Sculean, Blanca Fernandez-Tome, Gavriel Chaushu
Summary: The study evaluated the impact of peri-implant disease on serum biochemical parameters in a dog model, showing that PID affects inflammatory and hepatic serum biochemical parameters. Most values returned to baseline after open flap debridement.
JOURNAL OF PERIODONTOLOGY
(2021)
Review
Biochemistry & Molecular Biology
Francesca Delucchi, Camilla Canepa, Luigi Canullo, Paolo Pesce, Gaetano Isola, Maria Menini
Summary: The aim of this systematic review is to summarize current knowledge on the use of biomarkers extracted from peri-implant crevicular fluid (PICF) as predictors of peri-implant bone loss (BL). A total of 158 entries were initially found, and after a full-text review and assessment of eligibility criteria, nine articles were selected. According to the review, several inflammatory biomarkers harvested from PICF seem to be correlated with peri-implant bone loss and may aid in diagnosing peri-implantitis early. MiRNA expression has shown predictive potential for peri-implant bone loss and may be useful for preventive and therapeutic purposes in implant dentistry.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Health Care Sciences & Services
Renzo Guarnieri, Alessio Zanza, Maurilio D'Angelo, Dario Di Nardo, Andrea Del Giudice, Alessandro Mazzoni, Rodolfo Reda, Luca Testarelli
Summary: This study analyzed the levels of peri-implant marginal bone loss and metalloproteinase-8 in different timeframes, finding a correlation between the two. Higher bone loss rates were associated with elevated metalloproteinase-8 levels, serving as predictive indicators for peri-implant marginal bone loss progression.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
S. Barootchi, L. Tavelli, J. Majzoub, H. L. Chan, H. L. Wang, O. D. Kripfgans
Summary: The study demonstrates that ultrasound color flow can serve as a valuable tool in evaluating the degree of clinical inflammation at implant sites and is directly correlated with clinical diagnoses.
JOURNAL OF DENTAL RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Florian Rathe, Rudiger Junker, Sabine Groger, Jorg Meyle, Markus Schlee
Summary: This study aimed to investigate the inflammatory effects of individualized abutments bonded onto titanium bases in implant prosthodontics. The results showed that there were no significant differences in bone level changes, clinical parameters, or Il-1 beta levels between test and control abutments. However, Il-1 beta levels were significantly elevated at 6 and 12 months follow-up compared to baseline in both groups.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
J. Martinez-Amargant, B. de Tapia, A. Pascual, J. Takamoli, C. Esquinas, J. Nart, C. Valles
Summary: This study aimed to determine the association between tobacco and peri-implant diseases and investigate patient- and implant-related variables associated with peri-implant diseases. Data from 117 patients treated with implant-supported restorations were analyzed, and the study found that smoke intensity was associated with an increased risk of peri-implant diseases.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Masumeh Babayi, Mohammed N. Ashtiani, Amirhossein Emamian, Hosseinali Ramezanpour, Hashem Yousefi, Majid Mahdavi
Summary: This study investigated the effect of immediate versus delayed dental implant placement strategies on cell differentiation. The results showed that delayed loading led to greater bone formation than immediate loading. In the delayed strategy, bone cells were appropriately supplied during the first few weeks following surgery, resulting in higher and faster secondary stability of the dental implant.
ARCHIVES OF ORAL BIOLOGY
(2023)
Review
Medicine, Research & Experimental
Carlos Henrique Alves, Karolayne Larissa Russi, Natalia Conceicao Rocha, Fabio Bastos, Michelle Darrieux, Thais Manzano Parisotto, Raquel Girardello
Summary: In recent decades, there have been significant advances in ortho-aesthetic-functional rehabilitation with the introduction of implantology. However, there is still a percentage of failures in implantology surgeries, mainly due to infections caused by bacterial proliferation, fungi presence, and biofilm formation, leading to peri-implantitis. Various studies have been conducted to explore the interaction between the host-oral microbiome and the development of peri-implantitis. Peri-implantitis is associated with a diversity of bacterial species, with Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia being identified in higher proportions of peri-implantitis samples. In addition, the injury of peri-implant tissue triggers an inflammatory response mediated by the activation of innate immune cells, such as macrophages, dendritic cells, mast cells, and neutrophils. Activation of the host immune system may disrupt the balance of oral microbiota, leading to dysbiosis and the production of various substances that contribute to implant loss.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Review
Infectious Diseases
Asma Gasmi Benahmed, Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Oleksandr Avdeev, Yurii Shanaida, Geir Bjorklund
Summary: Dental implants are commonly used to replace lost teeth, and titanium implants have a high success rate. However, there is an increasing risk of peri-implantitis, an inflammatory disease that affects the tissues around the implant. This review highlights the impact of different metabolic conditions on peri-implantitis and emphasizes the importance of considering both local and systemic factors in dental implant procedures and treatment.
Article
Dentistry, Oral Surgery & Medicine
Karin Apaza-Bedoya, Maria Elisa Galarraga-Vinueza, Bruna Barbosa Correa, Frank Schwarz, Marco Aurelio Bianchini, Cesar Augusto Magalhaes Benfatti
Summary: This study assessed the prevalence and risk indicators of peri-implant diseases, and associated specific clinical characteristics with these diseases. In the medium term, peri-implant diseases were correlated with factors inherent to the patient's conditions, presurgical treatment plan, and hygiene maintenance care.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Olivier Carcuac, Ingemar Abrahamsson, Georgios Charalampakis, Tord Berglundh
JOURNAL OF CLINICAL PERIODONTOLOGY
(2015)
Article
Dentistry, Oral Surgery & Medicine
O. Carcuac, J. Derks, G. Charalampakis, I. Abrahamsson, J. Wennstrom, T. Berglundh
JOURNAL OF DENTAL RESEARCH
(2016)
Article
Dentistry, Oral Surgery & Medicine
Olivier Carcuac, Jan Derks, Ingemar Abrahamsson, Jan L. Wennstroem, Max Petzold, Tord Berglundh
JOURNAL OF CLINICAL PERIODONTOLOGY
(2017)
Article
Dentistry, Oral Surgery & Medicine
Olivier Carcuac, Ingemar Abrahamsson, Jean-Pierre Albouy, Elena Linder, Lena Larsson, Tord Berglundh
CLINICAL ORAL IMPLANTS RESEARCH
(2013)
Article
Dentistry, Oral Surgery & Medicine
Georgios Charalampakis, Ingemar Abrahamsson, Olivier Carcuac, Gunnar Dahlen, Tord Berglundh
CLINICAL ORAL IMPLANTS RESEARCH
(2014)
Article
Dentistry, Oral Surgery & Medicine
Ahmed Almohandes, Olivier Carcuac, Ingemar Abrahamsson, Henrik Lund, Tord Berglundh
CLINICAL ORAL IMPLANTS RESEARCH
(2019)
Article
Dentistry, Oral Surgery & Medicine
Olivier Carcuac, Ingemar Abrahamsson, Jan Derks, Max Petzold, Tord Berglundh
CLINICAL ORAL IMPLANTS RESEARCH
(2020)
Article
Dentistry, Oral Surgery & Medicine
Olivier Carcuac, Jan Derks, Ingemar Abrahamsson, Jan L. Wennstrom, Tord Berglundh
CLINICAL ORAL IMPLANTS RESEARCH
(2020)
Article
Dentistry, Oral Surgery & Medicine
Carlotta Dionigi, Lena Larsson, Olivier Carcuac, Tord Berglundh
JOURNAL OF CLINICAL PERIODONTOLOGY
(2020)
Article
Dentistry, Oral Surgery & Medicine
Olivier Carcuac, Jan Derks
Summary: By modifying the free gingival graft technique, complete or almost complete root coverage was achieved in challenging gingival recession defects in the mandibular incisor area.
INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ingemar Abrahamsson, Olivier Carcuac, Tord Berglundh
Summary: The study aimed to compare the early stages of osseointegration around implants with different geometry following installation in sites using different osteotomy protocols. The results showed that the modified osteotomy protocol resulted in higher insertion torque and a correlation between insertion torque and radiographic bone loss after 6 weeks of healing. Implants in the test group had more pronounced decline in ISQ values during healing and presented with significantly higher BIC% in the mid and apical areas, indicating increased remodeling of cortical bone in undersized osteotomy sites.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Dentistry, Oral Surgery & Medicine
Ahmed Almohandes, Henrik Lund, Olivier Carcuac, Max Petzold, Tord Berglundh, Ingemar Abrahamsson
Summary: The accuracy of bone-level assessments using intra-oral peri-apical (PA) radiographs, cone-beam computed tomography (CBCT), and histology was evaluated in this study. The results showed that PA radiographs consistently overestimated bone levels compared to CBCT and histology. However, PA radiographs can still be considered a reliable technique for peri-implant bone-level evaluations.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Olivier Carcuac, Anna Trullenque-Eriksson, Jan Derks
Summary: This study evaluated the clinical and patient-reported outcomes of using conventional free gingival graft (FGG) or modified FGG (ModFGG) for treating RT1 gingival recession defects at mandibular incisors. The results showed that ModFGG had a higher root coverage rate at 1 year compared to FGG (91.8% vs. 60.7%) and significantly improved the height of keratinized tissue (4.2mm vs. 2.2mm) with less shrinkage. ModFGG also had lower post-surgical morbidity at 2 weeks and higher patient satisfaction at 12 months.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Olivier Carcuac, Leif Jansson
SWEDISH DENTAL JOURNAL
(2010)