Article
Endocrinology & Metabolism
Markus A. Hartmann, Stephane Blouin, Barbara M. Misof, Nadja Fratzl-Zelman, Paul Roschger, Andrea Berzlanovich, Gerlinde M. Gruber, Peter C. Brugger, Jochen Zwerina, Peter Fratzl
Summary: The study compared BMDD between different types of SEM devices and found that increasing pixel resolution resulted in shifts of BMDD peak and width to higher values. The inter-device reproducibility of mean calcium content showed a difference of up to 1wt% Ca, while technical variance could be reduced to +/- 0.17wt% Ca.
CALCIFIED TISSUE INTERNATIONAL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Katherine N. Haseltine, Tariq Chukir, Pinar J. Smith, Justin T. Jacob, John P. Bilezikian, Azeez Farooki
Summary: Bone mineral density measurement and FRAX assessment tools can help evaluate fracture risk and guide decisions for osteoporosis pharmacologic treatment. Specific populations like postmenopausal women and men over 50 should receive pharmacologic treatment according to guidelines. Monitoring BMD regularly and considering secondary causes or non-compliance is important during treatment.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Article
Endocrinology & Metabolism
Ji Hyun Lee, JooYong Park, Jung Hee Kim, Ji-Yeob Choi, Hyung Jin Choi, Eu Jeong Ku, A. Ram Hong, Chan Soo Shin, Nam H. Cho
Summary: This Korean prospective cohort study found that decreasing waist circumference and lean muscle mass loss were significant risk factors for hip bone loss in both men and women. Other factors may have sex-specific or age-specific effects on hip bone loss. None of the genetic factors tested were associated with hip bone loss after multiple testing adjustments, indicating that modifiable factors may play a larger role in determining bone health.
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhenghua Liu, Dageng Huang, Yonghong Jiang, Xiaowen Ma, Yuting Zhang, Rong Chang
Summary: This study investigated the correlation between R2* and vertebral fat fraction (FF) and bone mineral density (BMD), and explored its role in the quantitative assessment of osteoporosis (OP). The results showed that R2* was significantly correlated with FF and BMD. In addition, the area under the curve (AUC) for FF in diagnosing OP was higher than that for R2*. Therefore, R2* can be used as a complement to FF and BMD for the quantitative assessment of OP.
EUROPEAN RADIOLOGY
(2023)
Review
Construction & Building Technology
Lihui Li, Jian Yang, WangWei Liu, Pengfei Ren
Summary: This paper provides insights into selecting a suitable and reliable quantitative backscattered electron (QBSE) image analysis method for studying microstructure evolution in cement-based materials. It focuses on the technical principles, sample preparation, and the development of QBSE image analysis methods. The advantages and limitations associated with QBSE image analysis are also discussed.
CONSTRUCTION AND BUILDING MATERIALS
(2023)
Article
Orthopedics
Feng Zhou, Bo Sheng, Furong Lv
Summary: The objective of this study was to investigate the correlation between FF, R2* value of IDEAL-IQ sequence and bone mineral density (BMD), and to explore their application value in osteoporosis. The results showed that FF and R2* value were correlated with BMD, providing valuable information for the assessment of bone health.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yung-Chieh Chen, Yi-Tien Li, Po-Chih Kuo, Sho-Jen Cheng, Yi-Hsiang Chung, Duen-Pang Kuo, Cheng-Yu Chen
Summary: This study developed a diagnostic tool combining machine learning segmentation and radiomic texture analysis for bone density screening using chest low-dose computed tomography (LDCT). The tool showed high accuracy in classifying abnormal bone density and distinguishing osteoporosis. The combination of ML segmentation and RTA is a feasible approach for osteoporosis screening during lung cancer screening.
EUROPEAN RADIOLOGY
(2023)
Review
Nutrition & Dietetics
Elham Kazemian, Ali Pourali, Fatemeh Sedaghat, Mehrdad Karimi, Vahid Basirat, Zohreh Sajadi Hezaveh, Sayed Hossein Davoodi, Michael F. Holick
Summary: A systematic review and meta-analysis evaluated the effects of vitamin D-3 supplementation on bone health in adults. The results showed a protective effect of vitamin D-3 supplementation on bone mineral density (BMD) at the lumbar spine, femoral neck, and total hip. Dose-response analysis revealed a linear relationship between vitamin D-3 supplementation doses and BMD. However, no significant effect of vitamin D-3 supplementation on whole-body or total hip BMD was found. The relationship between vitamin D-3 supplement doses and markers of bone turnover was nonlinear.
Article
Endocrinology & Metabolism
Nadja Fratzl-Zelman, Katherine Wesseling-Perry, Riikka E. Makitie, Stephane Blouin, Markus A. Hartmann, Jochen Zwerina, Ville-Valtteri Valimaki, Christine M. Laine, Matti J. Valimaki, Renata C. Pereira, Outi Makitie
Summary: Patients with WNT1 or PLS3 mutations show unique bone mineralization patterns, with teriparatide having little effect on their bone matrix mineralization or formation. Children exhibit preserved bone formation with heterogeneous mineralization, while adults show low bone turnover with homogenous mineral content.
Article
Nutrition & Dietetics
Raul Roncero-Martin, Ignacio Aliaga, Jose M. Moran, Luis M. Puerto-Parejo, Purificacion Rey-Sanchez, Maria de la Luz Canal-Macias, Antonio Sanchez-Fernandez, Juan D. Pedrera-Zamorano, Fidel Lopez-Espuela, Vicente Vera, Purificacion Cerrato-Carretero, Jesus M. Lavado-Garcia
Summary: The study found a significant positive association between plasma n-3 polyunsaturated fatty acid levels and bone density in Spanish postmenopausal women, independent of BMI and total plasma n-3 PUFAs.
Article
Endocrinology & Metabolism
Jin Liu, Jian-Wei Liao, Wei Li, Xiao-Jun Chen, Jia-Xin Feng, Lin Yao, Pan-Hui Huang, Zhi-Hai Su, Hai Lu, Yu-Ting Liao, Shao-Lin Li, Ya-Jun Ma
Summary: In this study, the CBWPD measured by STAIR-UTE MRI was shown to be a promising biomarker in the diagnosis of osteoporosis and the assessment of bone quality and fracture risk.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Endocrinology & Metabolism
Mingwei Hu, Yifan Zhang, Jianjun Guo, Cuicui Guo, Xue Yang, Xue Ma, Hao Xu, Shuai Xiang
Summary: This study evaluated the changes in bone mineral density and bone turnover markers after denosumab and romosozumab therapies in patients with osteoporosis. The results showed that the romosozumab group exhibited greater changes in lumbar BMD and bone turnover markers at 3 months of treatment, while changes in BMD of total hip and femoral neck were relatively delayed. From 6 to 12 months of treatment, romosozumab showed greater changes in bone mineral density and markers of bone turnover.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Endocrinology & Metabolism
Panagiotis Anagnostis, Kalliopi Lampropoulou-Adamidou, Julia K. Bosdou, Georgios Trovas, Petros Galanis, Efstathios Chronopoulos, Dimitrios G. Goulis, Symeon Tournis
Summary: The optimal management of pregnancy and lactation-associated osteoporosis (PLO) has not been determined. Existing studies have found that calcium/vitamin D, bisphosphonates, and teriparatide can improve bone mineral density, with teriparatide showing better efficacy. However, due to heterogeneity and lack of robust comparative data, safe conclusions cannot be drawn regarding the optimal therapeutic intervention in women with PLO.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Food Science & Technology
Francine R. F. Silva, Joyce E. Heredia, Leticia F. Duffles, Onno J. Arntz, Mauro M. Teixeira, Adaliene V. M. Ferreira, Tarcilia A. Silva, Fons A. J. van de Loo, Soraia Macari, Marina C. Oliveira
Summary: Treatment with bovine milk extracellular vesicles (MEVs) improves alveolar bone loss in ovariectomized (OVX) mice by reducing bone remodeling movement and increasing osteoblast and osteocyte number. MEVs treatment also decreases RANKL/OPG ratios and osteoclasts and odontoclasts activity in the maxillary bone.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Endocrinology & Metabolism
William D. Leslie, Heenam Goel, Neil Binkley, Eugene McCloskey, Didier Hans
Summary: Lumbar spine trabecular bone score (TBS) is a bone mineral density (BMD)-independent risk factor for fracture, but its sensitivity to technical factors and oral antiresorptive therapies is limited. This study analyzed TBS changes over time and in response to osteoporosis treatment, and found that TBS is strongly affected by technical factors and has little effect on monitoring response to antiresorptive treatment. Therefore, the current version of the TBS algorithm has limited usefulness in untreated individuals or routine clinical practice.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Engineering, Biomedical
Urszula Stachewicz, Tuya Qiao, Simon C. F. Rawlinson, Filipe Veiga Almeida, Wei-Qi Li, Michael Cattell, Asa H. Barber
ACTA BIOMATERIALIA
(2015)
Article
Engineering, Biomedical
Mei Huang, Robert G. Hill, Simon C. F. Rawlinson
ACTA BIOMATERIALIA
(2016)
Editorial Material
Dentistry, Oral Surgery & Medicine
Jie Liu, Simon C. F. Rawlinson, Robert G. Hill, Farida Fortune
Article
Engineering, Biomedical
Kaveh Memarzadeh, Amir S. Sharili, Jie Huang, Simon C. F. Rawlinson, Robert P. Allaker
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2015)
Article
Dentistry, Oral Surgery & Medicine
S. C. F. Rawlinson, A. Boyde, G. R. Davis, P. G. T. Howell, F. J. Hughes, V. J. Kingsmill
JOURNAL OF DENTAL RESEARCH
(2009)
Article
Dentistry, Oral Surgery & Medicine
Virginia J. Kingsmill, Ian J. McKay, Paul Ryan, Matthew R. Ogden, Simon C. F. Rawlinson
JOURNAL OF DENTISTRY
(2013)
Article
Materials Science, Ceramics
Ahmed Al-Noaman, Simon C. F. Rawlinson, Robert G. Hill
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2012)
Article
Materials Science, Ceramics
Ahmed Al-Noaman, Simon C. F. Rawlinson, Robert G. Hill
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2012)
Article
Materials Science, Ceramics
Ahmed Al-Noaman, Natalia Karpukhina, Simon C. F. Rawlinson, Robert G. Hill
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2013)
Article
Materials Science, Ceramics
Ahmed Al-Noaman, Natalia Karpukhina, Simon C. F. Rawlinson, Robert G. Hill
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2013)
Article
Materials Science, Multidisciplinary
Ahmed Al-Noaman, Simon C. F. Rawlinson, Robert G. Hill
Article
Multidisciplinary Sciences
Simon C. F. Rawlinson, Ian J. Mckay, Mandeep Ghuman, Claudia Wellmann, Paul Ryan, Saengsome Prajaneh, Gul Zaman, Francis J. Hughes, Virginia J. Kingsmill
Article
Dentistry, Oral Surgery & Medicine
Ahmed Al-Noaman, Simon Charles Fielding Rawlinson
Summary: A composite coating of bioactive glass and graphene oxide was prepared to enhance the biocompatibility and bioactivity of PEEK. The coating displayed strong adhesion, non-toxicity, improved wettability, and promoted apatite formation in simulated body fluid.
EUROPEAN JOURNAL OF ORAL SCIENCES
(2023)
Article
Multidisciplinary Sciences
Urszula Stachewicz, Tuya Qiao, Simon C. F. Rawlinson, Filipe Veiga Almeida, Wei-Qi Li, Michael Cattell, Asa H. Barber