4.7 Article

Technical note: Efficient parentage assignment and pedigree reconstruction with dense single nucleotide polymorphism data

期刊

JOURNAL OF DAIRY SCIENCE
卷 94, 期 4, 页码 2114-2117

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ELSEVIER SCIENCE INC
DOI: 10.3168/jds.2010-3896

关键词

parentage; single nucleotide polymorphism; efficient

资金

  1. Dairy Futures Cooperative Research Centre (Melbourne, Australia)

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Large numbers of dairy cattle are now routinely genotyped for dense single nucleotide polymorphism (SNP) arrays for the purpose of predicting genomic estimated breeding values. Such SNP arrays contain very good information for parentage assignment and pedigree reconstruction. The main challenge in using this information for parentage assignment and pedigree reconstruction is development of computationally efficient strategies that enable a candidate animal to be assigned its sire and darn with the large volume of data. Here we describe an efficient algorithm for parentage assignment with SNP data and demonstrate very accurate assignment with 50,000-SNP and 3,000-SNP panels. The computer code implementing the algorithm is given in the Appendix.

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