Review
Immunology
Anastasia N. Vlasova, Linda J. Saif
Summary: The growing world population has put increasing pressure on the cattle industry, with the expansion of milk and beef production leading to greater risks of infectious diseases. Understanding cattle immune function is crucial for combating pathogens and improving food security.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Rodrigo M. Souza, Fernando N. Souza, Camila F. Batista, Sofie Piepers, Anneleen De Visscher, Kamila R. Santos, Paula C. Molinari, Jose A. Ferronatto, Adriano Franca da Cunha, Maiara G. Blagitz, Guilherme G. da Silva, Francisco P. Renno, Monica M. O. P. Cerqueira, Marcos B. Heinemann, Sarne De Vliegher, Alice M. M. P. Della Libera
Summary: This study investigated the ability of different staphylococcal species to evade host defense mechanisms in dairy cows, specifically focusing on phagocytosis resistance and triggering of reactive oxygen species (ROS) production. The findings suggest that different staphylococcal species have varying abilities to resist phagocytosis and induce ROS production, which may contribute to their persistence and inflammation in causing mastitis.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Jensine Wilm, Volker Kromker, Carsten Kirkeby, Maya Gussmann
Summary: This is a study on lactational treatment of bovine mastitis, using a database-based analysis of electronic health records and somatic cell count data. The study found that the number of treatments for mastitis in dairy cattle has decreased over the past decade, while treatment duration has slightly increased. By considering factors related to individual cows and infection risk, the study explored the relative effect on cytological cure and provided insights for optimizing the use of antibiotics in dairy cattle in the future.
JOURNAL OF DAIRY SCIENCE
(2023)
Review
Agriculture, Dairy & Animal Science
Chiara Tommasoni, Enrico Fiore, Anastasia Lisuzzo, Matteo Gianesella
Summary: Mastitis is a common and economically significant disease in the dairy industry. The most common form is subclinical mastitis, which can lead to decreased milk production and increased risk of clinical mastitis. Due to concerns about antimicrobial resistance, there have been regulations and pressure to reduce prophylactic antimicrobial use. Selective dry therapy is recommended, where only cows or quarters suspected of infection are treated. Various methods have been reported for selecting infected cows or quarters. This article focuses on the management and diagnosis of mastitis in dairy cows, with a specific focus on on-farm diagnostic tools.
Article
Veterinary Sciences
Carsten Kirkeby, Tariq Halasa, Michael Farre, Galal Nazih Chehabi, Kaare Graesboll
Summary: This study investigated the transmission dynamics of Corynebacterium spp. in two Danish dairy cattle herds. It was found that these bacteria can be prevalent within the herd and transmit directly between cows. The study highlighted the importance of researching cost-effective control measures against Corynebacterium spp.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Carsten C. F. Walker, Jill L. Brester, Lorraine M. Sordillo
Summary: FM treatment improves both systemic and local oxidant status, reducing local markers of oxidative stress. It has differential effects on animals that survived the infection compared to those that died. Pre-existing inflammation and oxidant status greatly affect the efficacy of FM treatment.
Article
Veterinary Sciences
Ewerton de Souza Lima, Maiara Garcia Blagitz, Camila Freitas Batista, Alexandre Jose Alves, Artur Cezar de Carvalho Fernandes, Eduardo Milton Ramos Sanchez, Hugo Frias Torres, Soraia Araujo Diniz, Marcos Xavier Silva, Alice Maria Melville Paiva Della Libera, Fernando Nogueira de Souza
Summary: This study investigated the effects of BLV infection on mammary gland immunity in dairy cows. Results showed that BLV-infected dairy cows had a higher frequency of viable milk macrophages, while seronegative animals had a higher percentage of milk macrophages that phagocytosed Staphylococcus aureus. BLV infection did not affect the intracellular reactive oxygen and nitrogen species (RONS) production and phagocytosis intensity by milk macrophages.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Agronomy
Ramunas Antanaitis, Lina Anskiene, Karina Dzermeikaite, Dovile Baceninaite, Aloyzas Januskauskas, Kestutis Sincevicius, Walter Baumgartner, Anton Klein
Summary: The aim of this study was to determine the impact of subclinical mastitis treatment in dairy cattle on biomarkers registered with in-line sensors such as milk yield (MY), electric milk conductivity (EC), rumination time (RT), and somatic cell count (SCC). According to the results, treating cows with subclinical mastitis using SCC boluses and NSAIDs is effective.
Article
Immunology
Turner H. Swartz, Barry J. Bradford, Laman K. Mamedova
Summary: The study showed that BHB altered the immune response in dairy cows during an intramammary Streptococcus uberis challenge, leading to tolerance towards S. uberis rather than resistance. This suggests that macrophage immune responses to S. uberis can be altered via a GPR109A-dependent mechanism.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
T. H. Swartz, B. J. Bradford, J. S. Clay
Summary: Adverse prenatal environments can impact offspring health and performance. In dairy cattle, dam's mammary gland health, measured by somatic cell score (SCS), is associated with daughter's age at first calving (AFC), lactation SCS, and milk fat yield. These intergenerational effects may be linked to prenatal inflammation and epigenetic mechanisms.
JOURNAL OF DAIRY SCIENCE
(2021)
Review
Agriculture, Dairy & Animal Science
Ellen de Jong, Kayley D. McCubbin, David Speksnijder, Simon Dufour, John R. Middleton, Pamela L. Ruegg, Theo J. G. M. Lam, David F. Kelton, Scott McDougall, Sandra M. Godden, Alfonso Lago, Paeivi J. Rajala-Schultz, Karin Orsel, Sarne De Vliegher, Volker Kromker, Diego B. Nobrega, John P. Kastelic, Herman W. Barkema
Summary: The treatment of clinical mastitis (CM) and the use of antimicrobials for dry cow therapy account for a large amount of antimicrobial use (AMU) on dairy farms. However, recent advancements have allowed for the exclusion of nonsevere CM cases that are likely to be cured without antimicrobials, as well as cases with a low bacteriological cure rate. These advancements include the availability of rapid diagnostic tests and improved udder health management practices. This review provides an evidence-based protocol for selective CM treatment decisions, which can aid in reducing AMU, improving udder health, and benefiting farm economics.
JOURNAL OF DAIRY SCIENCE
(2023)
Review
Agriculture, Dairy & Animal Science
Andra Sabina Neculai-Valeanu, Adina Mirela Ariton, Bianca Maria Madescu, Cristina Mihaela Rimbu, Steofil Creanga
Summary: Bovine mastitis is a prevalent and costly illness in dairy industries, with the potential to revolutionize by utilizing nanotechnology for novel treatment options. The key lies in increasing milk quality, maintaining market share, and developing innovative products to address antimicrobial resistance and provide sustainable animal health solutions. Nanomaterials offer promise in transforming veterinary medicine and animal production by offering new approaches to tackling challenging diseases like bovine mastitis.
Article
Agriculture, Dairy & Animal Science
Bart H. P. van den Borne, Niek J. M. van Grinsven, Henk Hogeveen
Summary: Studies have shown that transitioning from a conventional milking system to an automatic milking system may lead to udder health deteriorations, but these deteriorations have decreased in magnitude in recent years.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
A. M. Maisano, M. Luini, A. Gazzola, L. Sala, F. Vezzoli, L. Bertocchi, V. Lorenzi, P. Cremonesi, B. Castiglioni, S. Bergagna, A. Romano, E. Scaltriti, L. Bolzoni, I. Ivanovic, H. U. Graber
Summary: Staphylococcus aureus is a major pathogen causing mastitis in dairy cattle worldwide. The gene adlb is associated with the contagiousness of Staph. aureus CC8 strains, which have a high prevalence of intramammary infections (IMI). Environmental and milking management factors have minimal impact on the prevalence of Staph. aureus IMI.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Immunology
Luciana Hernandez, Enriqueta Bottini, Jimena Cadona, Claudio Cacciato, Cristina Monteavaro, Ana Bustamante, Andrea Mariel Sanso
Summary: This study characterized molecular features of S. agalactiae strains causing bovine mastitis in Argentina, revealing serotypes III and II as the most prevalent, virulence genes spb1, hylB, cylE, and PI-2b present in all isolates, and varied frequencies of antibiotic resistance genes.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
K. Leelahapongsathon, Y. H. Schukken, A. Srithanasuwan, W. Suriyasathaporn
JOURNAL OF DAIRY SCIENCE
(2020)
Article
Agriculture, Dairy & Animal Science
S. Notcovich, N. B. Williamson, S. Flint, J. Yapura, Y. H. Schukken, C. Heuer
JOURNAL OF DAIRY SCIENCE
(2020)
Article
Agriculture, Dairy & Animal Science
A. De Prado-Taranilla, M. M. C. Holstege, L. Bertocchi, A. Appiani, O. Becvar, J. Davidek, D. Bay, L. M. Jimenez, N. Roger, V Kromker, J. H. Paduch, S. Piepers, A. Wuytack, A. Veenkamp, T. van Werven, B. Dalez, P. Le Page, Y. H. Schukken, A. G. J. Velthuis
JOURNAL OF DAIRY SCIENCE
(2020)
Article
Agriculture, Dairy & Animal Science
D. Valckenier, S. Piepers, Y. H. Schukken, A. De Visscher, F. Boyen, F. Haesebrouck, S. De Vliegher
Summary: The study found that IMI caused by Staphylococcus chromogenes had longer duration compared to IMI caused by other NAS species, with only a small percentage persisting for more than 2 days; Quarters with higher qSCC usually had IMI caused by major pathogens, followed by S. chromogenes and other NAS species.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Multidisciplinary Sciences
Kristina M. Ceres, Ynte H. Schukken, Yrjo T. Grohn
Article
Multidisciplinary Sciences
Joaquin Barca, Ynte H. Schukken, Ana Meikle
Summary: The study aimed to determine if parity influenced the effect of PEG treatment on WBC counts in grazing dairy cows, finding that it was independent of parity. In the control group, Pre-NEFA concentration was associated with reduced WBC, neutrophil, and lymphocyte counts.
Article
Biotechnology & Applied Microbiology
Vincent P. Richards, Annette Nigsch, Paulina Pavinski Bitar, Qi Sun, Tod Stuber, Kristina Ceres, Rebecca L. Smith, Suelee Robbe Austerman, Ynte Schukken, Yrjo T. Grohn, Michael J. Stanhope
Summary: This study conducted a prolonged longitudinal analysis of MAP isolates and dairy cow Johne's disease phenotypes from three commercial dairy farms, identifying several genes associated with the disease. The results provide insights for improving strategies to control Johne's disease.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Annette Nigsch, Suelee Robbe-Austerman, Tod P. Stuber, Paulina D. Pavinski Bitar, Yrjo T. Grohn, Ynte H. Schukken
Summary: Recent evidence suggests the circulation of multiple MAP strains and mixed infections within cow herds, which calls for a rethink of MAP epidemiology knowledge. Strain typing has opened new avenues for investigating MAP transmission. The study showed that infection chains and spreading patterns could be quantified by linking genomic data with field data in a well-managed dairy herd.
Article
Multidisciplinary Sciences
Joaquin Barca, Ana Meikle, Mette Bouman, Giovanni Gnemmi, Rodrigo Ruiz, Ynte H. Schukken
Summary: In this study, it was found that pegbovigrastim treatment reduces the occurrence of clinical mastitis in dairy cows, particularly in those at higher risk of elevated lipid mobilization. However, the treatment did not have an impact on retained placenta or metritis occurrence. Additionally, cows treated with pegbovigrastim for metritis showed improved uterine healing process compared to control cows.
Article
Agriculture, Dairy & Animal Science
Joaquin Barca, Ana Meikle, Mette Bouman, Ynte H. Schukken
Summary: This study found that the impact of PEG treatment on fertility and culling interacts with pre-NEFA levels. In high pre-NEFA cows, PEG treatment increased the rate of first insemination, countered the negative effects of early-lactation CM and UD on pregnancy rates, and decreased the hazard of culling.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Maarten F. Weber, Marian Aalberts, Thomas Dijkstra, Ynte H. Schukken
Summary: In the Dutch paratuberculosis control program, test-negative herds with a preferred status may still have an increased risk of positive ELISA results. Therefore, this study developed a predictive model to alert farmers with test-negative herds if they are at an increased risk of future positive ELISA results.
Article
Agriculture, Dairy & Animal Science
Joaquin Barca, Ynte H. Schukken, Ana Meikle, Pablo Chilibroste, Mette Bouman, H. Hogeveen
Summary: This randomized controlled trial examined the effects of pegbovigrastim (PEG) treatment on the partial net return of grazing dairy cows. The study found that PEG treatment increased the partial net return and resulted in an economic benefit of $210 ± $100 per cow per year. It also reduced the cost of treatment for clinical mastitis and numerically reduced the cost of culling.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Veterinary Sciences
Julia A. Hertl, Ynte H. Schukken, Loren W. Tauer, Francis L. Welcome, Yrjo T. Grohn
Summary: The objective of this observational study was to investigate the relationship between clinical mastitis (CM) occurring in the first 100 days of a dairy cow's first lactation and her total productive lifetime. Data were collected from 24,831 cows in 5 New York Holstein herds. Two analytical approaches were compared: separate survival analyses treating removals (death, sale) as competing events, and traditional survival analysis using Cox proportional hazards models. The findings showed that certain pathogens were associated with either higher hazard rates of death or sale. The study highlights the importance of optimizing management strategies for cows with specific types of CM early in their productive lifetime.
PREVENTIVE VETERINARY MEDICINE
(2023)
Article
Agriculture, Dairy & Animal Science
Achmad Fadillah, Bart H. P. van den Borne, Okti Nadia Poetri, Henk Hogeveen, Wendy Umberger, Jack Hetherington, Ynte H. Schukken
Summary: This study investigates the awareness of Indonesian smallholder dairy farmers regarding milk quality parameters and identifies factors associated with total plate count (TPC) and somatic cell count (SCC) awareness. The study finds that most farmers have conceptual awareness of quality parameters but lack knowledge of their values. Factors such as cooperative membership, distance to other farmers, and information sources significantly influence farmers' awareness. Cooperatives play a crucial role in increasing smallholder farmers' awareness of milk quality parameters.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Veterinary Sciences
Shirli Notcovich, Norman B. Williamson, Jimena Yapura, Ynte Schukken, Cord Heuer
VETERINARY SCIENCES
(2020)