期刊
JOURNAL OF CROHNS & COLITIS
卷 4, 期 5, 页码 567-574出版社
OXFORD UNIV PRESS
DOI: 10.1016/j.crohns.2010.06.001
关键词
Ulcerative colitis; ECCO clinical guidelines; Inflammatory bowel disease; 5 ASA; Mesalazine; Questionnary
Background & aims A European consensus on the management of ulcerative colitis (UC) was recently published, however, there is no adequate evidence about adherence to such guidelines among gastroenterologists This knowledge would allow the local evaluation of the situation and the adoption of actions to reduce the existent clinical variability Methods A cross sectional survey was conducted in Spain to assess the adherence to the European Crohn s and Colitis Organisation (ECCO) guidelines on mild to moderate UC We surveyed 700 gastroenterologists, and finally a total of 530 gastroenterologists specialised in inflammatory bowel disease (GSIBDs) and general gastroenterologists (GGs), responded to the survey (76%) Results Agreement with the guidelines was high, discrepancies included that only 25% of the GGs used the combination of oral and topical 5 aminosalycilic acid (5 ASA) for treating extensive UC vs 45% of the GISBDs In addition, topical rectal steroids were considered as effective as topical mesalazine by 48% of the GGs vs 31% of the GSIBDs, indefinite treatment with 5 ASA was prescribed by only 26% of the GGs vs 41% of the GSIBDs, and the once daily dosing of 5 ASA was generally used by 46% of the GGs vs 51% of the GSIBDs Conclusions The questionnaire showed a high degree of agreement between GGs and GSIBDs Nevertheless, the GSIBD group showed closer agreement with the ECCO guidelines Furthermore, some shortcomings were found in the GG group, in which increased maintenance treatment with 5 ASA, the use of a single daily dose of 5 ASA, and the use of combined oral and topical treatment for distal colitis should be advised (C) 2010 European Crohn s and Colitis Organisation Published by Elsevier B V All rights reserved
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