Article
Surgery
Piotr Pietruski, Marcin Majak, Ewelina Swiatek-Najwer, Magdalena Zuk, Michal Popek, Marta Swiecka, Janusz Jaworowski, Maciej Mazurek
Summary: This study evaluates the accuracy of simulated maxillofacial skeleton osteotomies using cutting guides, simple augmented reality (sAR), and navigated augmented reality (nAR) modules. The results indicate that cutting guides provided the highest accuracy, followed by sAR and nAR.
INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY
(2023)
Article
Biochemistry & Molecular Biology
Lun-Jou Lo, Lien-Shin Niu, Chun-Hao Liao, Hsiu-Hsia Lin
Summary: The study presented the design, clinical application, and validation of a novel CAD/CAM occlusal splint that allows intraoperative judgment in single-splint two-jaw orthognathic surgery. The results showed no significant differences in parameters between the simulation and postoperative images, indicating the usefulness of the novel composite occlusal splint in verifying maxillomandibular position during surgery.
BIOMEDICAL JOURNAL
(2021)
Article
Engineering, Electrical & Electronic
Dongyue Li, Mingzhu Zhu, Shaoan Wang, Yaoqing Hu, Fusong Yuan, Junzhi Yu
Summary: A vision-based markerless surgical navigation system is developed to overcome the shortcomings in the currently available technologies in oral and maxillofacial surgery (OMS). Improvements in registration methods for patient and surgical instrument tracking are made to increase navigation performance. Experimental results validate the effectiveness and accuracy of the proposed system, providing practical guidance for OMS.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2023)
Article
Engineering, Biomedical
Yuichiro Hayashi, Kazunari Misawa, Kensaku Mori
Summary: A surgical navigation system is important for surgeons to understand anatomical structures during surgery. In this study, a compensation method using a database was proposed to reduce registration error in laparoscopic surgery navigation. The method involved analyzing positional information and averaging difference matrices computed from fiducial markers. The results demonstrated that the proposed method significantly decreased target registration error and improved the accuracy of laparoscopic surgery navigation.
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
(2023)
Article
Surgery
Joshua Yoon, Isabelle Lock, Caleb K. Fan, Uma Maduekwe, Michael Ha, Yvonne Rasko, Michael P. Grant, Arthur J. Nam, Jordan P. Steinberg, Fan Liang
Summary: The use of virtual 3D modeling and printing allows for the design and fabrication of accurate occlusal splints, which can serve as useful adjuncts in the operative reduction and fixation of complex maxillomandibular fractures, aiding in establishing premorbid occlusion and expediting fracture reduction and fixation.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Article
Oncology
Cheng-Hsien Wu, Yi-Yun Ho, Tzu-Lun Liu, Tzu-Ying Wu, Han-Chieh Cheng, Chieh-Chih Tsai
Summary: Orbital tumors can be approached surgically through transconjunctival medial orbitotomy or transnasal endoscopic approach. However, both methods have limitations. This study proposes a novel computer-assisted endoscopic protocol that allows excision of tumors and immediate repair of orbital wall defects.
FRONTIERS IN ONCOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Felix Schmeiser, Uwe Baumert, Bogna Stawarczyk
Summary: This study compared the two-body wear of occlusal splint materials fabricated from subtractive computer-aided manufacturing (CAM) and three-dimensional printing (3DP). The results showed that there was no significant difference in two-body wear between the materials fabricated using the two methods. However, the materials fabricated using 3DP were more likely to fracture, while those fabricated using CAM were more likely to perforate.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Orthopedics
Jonathan M. Vigdorchik, Peter K. Sculco, Allan E. Inglis, Ran Schwarzkopf, Jeffrey M. Muir
Summary: The study found that registering patients using a plane approximating the long axis of the body accurately measured cup position, while registering with a plane approximating the hip-shoulder axis provided the most accurate and consistent measurement of acetabular component position.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Surgery
Yikang Hou, Gang Chai, Zuoliang Qi
Summary: A new occlusal splint-based optical navigation system was developed for craniomaxillofacial surgery, with experiments on Beagle dogs showing that the system's accuracy meets clinical requirements. The study highlights the potential of the system as a useful tool to improve the accuracy of craniomaxillofacial surgery.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Article
Surgery
Honghao Wang, Yifan Chi, Hanxiao Huang, Shiheng Su, Haowei Xue, Jun Hou
Summary: This study summarizes the combined application of 3D printing technology and computer-aided navigation (CAN) for complex maxillofacial fractures. The results show that the combination of CAN and 3D printing significantly improves the treatment results of double-sided maxillofacial fractures and shortens the operation time.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Surgery
Niclas Hagen, Frederic Weichel, Reinald Kuehle, Petra Knaup, Christian Freudlsperger, Urs Eisenmann
Summary: This paper presents a novel approach for automated calculation of ontology-based planning proposals in mandibular reconstruction and conducts a feasibility study. The results show that the proposed method can calculate reconstruction proposals quickly and accurately, and is validated by expert evaluations.
INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY
(2023)
Article
Dentistry, Oral Surgery & Medicine
H. Y. Soh, L. H. Hu, Y. Yu, T. Wang, W. B. Zhang, X. Peng
Summary: The aim of this study was to assess the accuracy of navigation-assisted maxillofacial reconstruction and identify predictors of clinical outcomes. The results showed that navigation-assisted midface reconstruction achieved a higher level of accuracy compared to mandibular reconstruction. These findings suggest that computer-assisted techniques and intraoperative navigation can improve the final surgical outcome in complex maxillofacial reconstructions.
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2022)
Article
Surgery
Long Xia, Chunli Gao, Xi Gong, Yi Zhang, Yang He, Jingang An
Summary: This study compared postoperative enophthalmos between fresh and delayed unilateral orbital fractures after orbital reconstruction with titanium mesh using computer-assisted navigation. The findings showed that postoperative enophthalmos decreased after surgery but increased significantly from 1 week to 6 months postoperatively in both groups. Delta E (difference in the degree of enophthalmos between 1 week and 6 months postoperatively) was similar between patients with fresh and delayed fractures. There was a significant difference in Delta E between patients with single-wall orbital fractures and those with two-wall orbital fractures.
JOURNAL OF CRANIOFACIAL SURGERY
(2023)
Review
Chemistry, Multidisciplinary
Jwa-Young Kim, Yong-Chan Lee, Seong-Gon Kim, Umberto Garagiola
Summary: This comprehensive review explores the integration of 3D printing and Virtual Surgical Planning (VSP) in orthognathic and oral maxillofacial surgery, which enables personalized surgical methods, precise planning through tactile 3D models, and accurately designed surgical guides for improved patient-centric care and predictable outcomes.
APPLIED SCIENCES-BASEL
(2023)
Review
Health Care Sciences & Services
Juliana F. Sabelis, Ruud Schreurs, Harald Essig, Alfred G. Becking, Leander Dubois
Summary: Restoring the orbit is the initial and most predictable step in the surgical treatment of orbital fractures. Computer-assisted surgery (CAS) technology has become the standard for complex orbital traumatology, allowing for personalized medicine in orbital reconstruction. The workflow includes diagnostics, planning, surgery, and evaluation, utilizing advanced diagnostics and virtual surgical planning for optimal preparation and personalized treatment. Intraoperatively, visual appraisal and CAS technology enhance feedback, and the surgical result can be evaluated qualitatively and quantitatively.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Engineering, Mechanical
Qimin Shi, Yi Sun, Shoufeng Yang, Jeroen Van Dessel, Heinz-Theo Luebbers, Shengping Zhong, Yifei Gu, Michel Bila, Titiaan Dormaar, Joseph Schoenaers, Constantinus Politis
Summary: A multidimensional and comprehensive analysis of the in-vivo fatigue failure mechanism of an SLM-fabricated Ti6Al4V mandible reconstruction plate reveals that surface defects and maximal stress caused by implant design are the main factors for crack initiation and propagation, showing a combined brittle/ductile fracture mode. The process is influenced by Ca/P/O deposits and hydrogen embrittlement under the biological environment.
ENGINEERING FAILURE ANALYSIS
(2021)
Article
Oncology
Hongyang Ma, Sohaib Shujaat, Jeroen Van Dessel, Yi Sun, Michel Bila, Jan Vranckx, Constantinus Politis, Reinhilde Jacobs
Summary: The study aimed to investigate adherence to planned maxillofacial reconstructions using computer-assisted surgery (CAS) and identified influential factors affecting compliance. Factors influencing compliance included defect size, bone flap segments, and type of disease. Patients with smaller defects showed higher CAS compliance, while those with multiple bone flap segments were more likely to have partial or complete abandonment of CAS.
FRONTIERS IN ONCOLOGY
(2021)
Article
Biology
Qimin Shi, Yi Sun, Shoufeng Yang, Jeroen Van Dessel, Heinz-Theo Lubbers, Shengping Zhong, Yifei Gu, Michel Bila, Constantinus Politis
Summary: The combination of long and short titanium plates showed superior biomechanical properties for mandible reconstruction compared to a conventional single long plate. It provided higher safety, lower fixation instability, and good bone segment stability during masticatory activities. This preclinical evidence supports the feasibility of using short plates for complete mandible reconstruction and may have implications for treating other large-sized bone defects with customised implants using additive manufacturing technology.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Otorhinolaryngology
Frederik Peeters, Jeroen Van Dessel, Tomas-Marijn Croonenborghs, Maximiliaan Smeets, Yi Sun, Robin Willaert, Constantinus Politis, Michel Bila
Summary: This study compared the performance of six comorbidity scales in predicting overall survival in patients with oral squamous cell carcinoma (OSCC) after surgery. The selected comorbidity scales were found to be capable of predicting overall survival for OSCC patients 2 and 5 years after primary surgery.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Review
Orthopedics
Yifei Gu, Yi Sun, Sohaib Shujaat, Annabel Braem, Constantinus Politis, Reinhilde Jacobs
Summary: This systematic review evaluates the osteogenic potential of 3D-printed porous Ti6Al4V (Ti64) scaffold for repairing long bone defects in animal models and investigates the influential factors affecting its osteogenic capacity. The analysis reveals that a specific pore size and porosity can optimize bone formation, demonstrating potential clinical value in providing mechanical support and a stable environment for new bone formation.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Materials Science, Multidisciplinary
Yifei Gu, Lingfei Wei, Zheru Zhang, Jeroen Van Dessel, Ronald B. Driesen, Ivo Lambrichts, Reinhilde Jacobs, Lei Tian, Yi Sun, Yuelian Liu, Constantinus Politis
Summary: In this study, a porous Ti6Al4V scaffold with a biomimetic coating was designed and implanted in beagle dogs. The results showed that the coating induced ectopic bone formation and increased biocompatibility of the scaffold. This combination has the potential for bone reconstruction, but further clinical studies are needed.
MATERIALS & DESIGN
(2022)
Article
Materials Science, Multidisciplinary
Lei Nie, Jie Li, Guoqi Lu, Xiaoyan Wei, Yaling Deng, Shuang Liu, Shengping Zhong, Qimin Shi, Ruixia Hou, Yi Sun, Constantinus Politis, Lihong Fan, Oseweuba Valentine Okoro, Amin Shavandi
Summary: A newly developed temperature-responsive hydrogel with interpenetrating polymer networks has shown excellent cytocompatibility towards human bone marrow mesenchymal stem cells (hBMSCs). The critical solution temperature (LCST) can be regulated by changing the weight ratio of the components. Cell encapsulation and 3D culturing in the hydrogel at a specific temperature range have been successfully achieved.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Hongyang Ma, Jeroen Van Dessel, Sohaib Shujaat, Michel Bila, Yi Sun, Constantinus Politis, Reinhilde Jacobs
Summary: The aim of this study was to evaluate the 5-year cumulative survival rate of implant-based dental rehabilitation after maxillofacial reconstruction with a vascularized bone flap and to identify potential risk factors influencing the survival rate. The results showed a cumulative survival rate of 96%, 87%, and 81% at 1, 2, and 5 years, respectively. Patients with systemic diseases, irradiated flap, and poor oral hygiene had a significantly higher risk of implant failure.
INTERNATIONAL JOURNAL OF IMPLANT DENTISTRY
(2022)
Article
Materials Science, Ceramics
Shengping Zhong, Qimin Shi, Yaling Deng, Yi Sun, Constantinus Politis, Shoufeng Yang
Summary: NanoParticle Jetting (NPJ), a novel material jetting process, is capable of fabricating dense zirconia components with a highly detailed surface and remarkable mechanical properties. The experimental results of NPJ-printed ZrO2 cuboids showed high relative density, glossy surface, controllable shrinkage, and outstanding mechanical properties. The innovative NPJ system has significant potential for additive manufacturing.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Multidisciplinary
Qimin Shi, Shoufeng Yang, Yi Sun, Yifei Gu, Ben Mercelis, Shengping Zhong, Bart Van Meerbeek, Constantinus Politis
Summary: This work compares the microstructure, mechanical properties, and wear performance of two Ti-Mo biomaterials prepared by Selective Laser Melting (SLM) with different synthesis mechanisms. The in-situ Ti-7.5Mo-2.4TiC composites show improved mechanical strength and wear resistance compared to Ti-7.5Mo alloys, despite having a higher elastic modulus.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2022)
Article
Computer Science, Interdisciplinary Applications
Shengping Zhong, Qimin Shi, Jeroen Van Dessel, Yifei Gu, Yi Sun, Shoufeng Yang, Constantinus Politis
Summary: The study validates the biomechanical benefit of the structural optimized patient-specific mandibular reconstruction plates (PSMRPs) compared to the original design. PSMRP1 shows better biomechanical performance in patient-specific mandibular reconstruction than PSMRP2, while PSMRP2 provides biomechanical benefit in reducing the maximum tension.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Nanoscience & Nanotechnology
Qimin Shi, Shoufeng Yang, Yi Sun, Bart Van Meerbeek, Constantinus Politis
Summary: This study demonstrates an in-situ microscale composition modulation method using laser powder bed fusion, achieving a balanced combination of mechanical and wear properties in metal composites. The modulation method creates a pathway for material design and performance customization in biomedical applications.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2022)
Article
Materials Science, Multidisciplinary
Yifei Gu, Yiwen Liu, Reinhilde Jacobs, Lingfei Wei, Yi Sun, Lei Tian, Yuelian Liu, Constantinus Politis
Summary: Porous scaffolds can have improved biocompatibility and osteoconductivity by using coating technique to create micro-and nanostructures on the surfaces. This study employed a biomimetic approach to coat porous titanium scaffolds with a bone morphogenetic protein-2 (BMP-2) integrated calcium phosphate (CaP) coating. In vitro characterizations demonstrated that the coated scaffolds exhibited mechanical properties similar to human cortical bone and released BMP-2 effectively. In vivo experiments on beagle dogs with mandibular defects showed that the biomimetic coating significantly promoted bone formation in the titanium scaffolds.
MATERIALS & DESIGN
(2023)
Article
Engineering, Biomedical
Shengping Zhong, Qimin Shi, Jeroen Van Dessel, Yifei Gu, Heinz-Theo Luebbers, Shoufeng Yang, Yi Sun, Constantinus Politis
Summary: The use of the non-locking system is feasible for patient-specific mandibular reconstruction with fibular free flaps. The non-locking system can be matched with customized bone plates, providing adequate safety and stability, and its biomechanics are similar to the locking system.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Surgery
Xiaojun Chen, Yang Li, Lu Xu, Yi Sun, Constantinus Politis, Xiaoyi Jiang
Summary: A novel surgical navigation system was developed to track the surgical saw in real-time and navigate the loosened bone graft under guidance until it aligned with the preoperatively planned position. Phantom experiments validated the feasibility of the system, showing a mean error of image-guided repositioning at 1.03 +/- 0.10mm, significantly more accurate than non-navigated methods at 5.57 +/- 1.40mm.
COMPUTER ASSISTED SURGERY
(2021)
