标题
Developmental Changes in Pharmacokinetics and Pharmacodynamics
作者
关键词
-
出版物
JOURNAL OF CLINICAL PHARMACOLOGY
Volume 58, Issue -, Pages S10-S25
出版商
Wiley
发表日期
2018-09-25
DOI
10.1002/jcph.1284
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Developmental Pharmacokinetics in Neonates: Maturational Changes and Beyond
- (2018) Karel Allegaert et al. CURRENT PHARMACEUTICAL DESIGN
- Factors impacting unbound vancomycin concentrations in neonates and young infants
- (2018) Anne Smits et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Development and applications of a physiologically-based model of paediatric oral drug absorption
- (2018) T.N. Johnson et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Evidence-based drug treatment for special patient populations through model-based approaches
- (2017) Elke H.J. Krekels et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Caffeine Citrate Dosing Adjustments to Assure Stable Caffeine Concentrations in Preterm Neonates
- (2017) Gilbert Koch et al. JOURNAL OF PEDIATRICS
- Cytokine Biomarkers of Disease Activity and Therapeutic Response after Initiating Methotrexate Therapy in Patients with Juvenile Idiopathic Arthritis
- (2017) Ryan S. Funk et al. PHARMACOTHERAPY
- Perinatal and neonatal use of paracetamol for pain relief
- (2017) Karel Allegaert et al. Seminars in Fetal & Neonatal Medicine
- Protective effect of rhEPO on tight junctions of cerebral microvascular endothelial cells early following traumatic brain injury in rats
- (2016) Qian Zhiyuan et al. BRAIN INJURY
- Neonatal Maturation of Paracetamol (Acetaminophen) Glucuronidation, Sulfation, and Oxidation Based on a Parent–Metabolite Population Pharmacokinetic Model
- (2016) Sarah F. Cook et al. CLINICAL PHARMACOKINETICS
- Single dose, CYP2D6 genotype-stratified pharmacokinetic study of atomoxetine in children with ADHD
- (2016) JT Brown et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Age-mediated changes in the gastrointestinal tract
- (2016) Hamid A. Merchant et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Remifentanil: applications in neonates
- (2016) Mineto Kamata et al. Journal of Anesthesia
- Pharmacometric Approaches to Personalize Use of Primarily Renally Eliminated Antibiotics in Preterm and Term Neonates
- (2016) Mélanie Wilbaux et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Clinical Pharmacology Studies in Critically Ill Children
- (2016) Nilay Thakkar et al. PHARMACEUTICAL RESEARCH
- The Non-Linear Child: Ontogeny, Isoniazid Concentration, and NAT2 Genotype Modulate Enzyme Reaction Kinetics and Metabolism
- (2016) Zoe Rogers et al. EBioMedicine
- Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents
- (2015) Anne van Rongen et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Paediatric pharmacokinetics: key considerations
- (2015) Hannah Katharine Batchelor et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Development of Human Membrane Transporters: Drug Disposition and Pharmacogenetics
- (2015) Miriam G. Mooij et al. CLINICAL PHARMACOKINETICS
- Population Pharmacokinetics of Intravenous Paracetamol (Acetaminophen) in Preterm and Term Neonates: Model Development and External Evaluation
- (2015) Sarah F. Cook et al. CLINICAL PHARMACOKINETICS
- Neonatal drug therapy: The first frontier of therapeutics for children
- (2015) K Allegaert et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Functional Biomarkers: an Approach to Bridge Pharmacokinetics and Pharmacodynamics in Pediatric Clinical Trials
- (2015) Gregory Kearns et al. CURRENT PHARMACEUTICAL DESIGN
- Dosing Guidelines of Aminoglycosides in Neonates: A Balance Between Physiology and Feasibility
- (2015) Karel Allegaert et al. CURRENT PHARMACEUTICAL DESIGN
- The Impact of Hypothermia on the Pharmacokinetics of Drugs Used in Neonates and Young Infants
- (2015) P. Pokorna et al. CURRENT PHARMACEUTICAL DESIGN
- Pharmacodynamics of norepinephrine reuptake inhibition: Modeling the peripheral and central effects of atomoxetine, duloxetine, and edivoxetine on the biomarker 3,4-dihydroxyphenylglycol in humans
- (2015) William Kielbasa et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Ontogenic expression of human carboxylesterase-2 and cytochrome P450 3A4 in liver and duodenum: Postnatal surge and organ-dependent regulation
- (2015) Yi-Tzai Chen et al. TOXICOLOGY
- Similarities and Differences in Gastrointestinal Physiology Between Neonates and Adults: a Physiologically Based Pharmacokinetic Modeling Perspective
- (2014) Guo Yu et al. AAPS Journal
- Pupillometry: a non-invasive technique for pain assessment in paediatric patients
- (2014) M. A. Connelly et al. ARCHIVES OF DISEASE IN CHILDHOOD
- Urinary Biomarkers of Trimethoprim Bioactivation in Vivo Following Therapeutic Dosing in Children
- (2014) Leon van Haandel et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Enzymatic isotope dilution mass spectrometry (IDMS) traceable serum creatinine is preferable over Jaffe in neonates and young infants
- (2014) Karel Allegaert et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Clinical Pharmacology in Neonates: Small Size, Huge Variability
- (2014) Karel Allegaert et al. Neonatology
- Simultaneous Pharmacokinetic Modeling of Gentamicin, Tobramycin and Vancomycin Clearance from Neonates to Adults: Towards a Semi-physiological Function for Maturation in Glomerular Filtration
- (2014) Roosmarijn F. W. De Cock et al. PHARMACEUTICAL RESEARCH
- P-glycoprotein in the Developing Human Brain
- (2014) Jessica Lam et al. THERAPEUTIC DRUG MONITORING
- Paediatric oral biopharmaceutics: Key considerations and current challenges
- (2013) Hannah K. Batchelor et al. ADVANCED DRUG DELIVERY REVIEWS
- Pharmacometric Characterization of Efavirenz Developmental Pharmacokinetics and Pharmacogenetics in HIV-Infected Children
- (2013) Ahmed Hamed Salem et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Novel Maturation Function for Clearance of the Cytochrome P450 3A Substrate Midazolam from Preterm Neonates to Adults
- (2013) Ibrahim Ince et al. CLINICAL PHARMACOKINETICS
- Variability of Histamine Pharmacodynamic Response in Children With Allergic Rhinitis
- (2013) Bridgette L. Jones et al. JOURNAL OF CLINICAL PHARMACOLOGY
- A Neonatal Amikacin Covariate Model Can Be Used to Predict Ontogeny of Other Drugs Eliminated Through Glomerular Filtration in Neonates
- (2013) Roosmarijn F. W. De Cock et al. PHARMACEUTICAL RESEARCH
- Population Pharmacokinetics of Theophylline in Premature Korean Infants
- (2013) Sung Eun Kim et al. THERAPEUTIC DRUG MONITORING
- Proton Pump Inhibitors in Pediatrics
- (2013) Robert M. Ward et al. PEDIATRIC DRUGS
- Intestinal drug transporters: An overview
- (2012) Margarida Estudante et al. ADVANCED DRUG DELIVERY REVIEWS
- Impact of Obesity on Drug Metabolism and Elimination in Adults and Children
- (2012) Margreke J.E. Brill et al. CLINICAL PHARMACOKINETICS
- The Clinical Relevance of Plasma Protein Binding Changes
- (2012) Jason A. Roberts et al. CLINICAL PHARMACOKINETICS
- Cefazolin plasma protein binding and its covariates in neonates
- (2012) A. Smits et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Developmental expression of drug metabolizing enzymes: Impact on disposition in neonates and young children
- (2012) R.N. Hines INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
- (2012) Christine Vogel et al. NATURE REVIEWS GENETICS
- The Impact of Extracorporeal Life Support and Hypothermia on Drug Disposition in Critically Ill Infants and Children
- (2012) Enno D. Wildschut et al. PEDIATRIC CLINICS OF NORTH AMERICA
- Trends in Adverse Reactions to Trimethoprim-Sulfamethoxazole
- (2012) J. L. Goldman et al. PEDIATRICS
- Effect of hypothermia and extracorporeal life support on drug disposition in neonates
- (2012) Enno D. Wildschut et al. Seminars in Fetal & Neonatal Medicine
- Critical Illness Is a Major Determinant of Midazolam Clearance in Children Aged 1 Month to 17 Years
- (2012) Ibrahim Ince et al. THERAPEUTIC DRUG MONITORING
- Method for predicting human intestinal first-pass metabolism of UGT substrate compounds
- (2012) Takako Furukawa et al. XENOBIOTICA
- Effects of Valproic Acid on Organic Acid Metabolism in Children: A Metabolic Profiling Study
- (2011) K E Price et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The Development of UDP-Glucuronosyltransferases 1A1 and 1A6 in the Pediatric Liver
- (2011) S. J. Miyagi et al. DRUG METABOLISM AND DISPOSITION
- Developmental Changes in P-Glycoprotein Function in the Blood-Brain Barrier of Nonhuman Primates: PET Study with R-11C-Verapamil and 11C-Oseltamivir
- (2011) T. Takashima et al. JOURNAL OF NUCLEAR MEDICINE
- Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues
- (2011) Michael H. Court et al. XENOBIOTICA
- Pharmacokinetics and pharmacodynamics of intravenous acetaminophen in neonates
- (2011) Karel Allegaert et al. Expert Review of Clinical Pharmacology
- The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response
- (2010) Mara L. Becker et al. ARTHRITIS AND RHEUMATISM
- Analysis of intracellular methotrexate polyglutamates in patients with juvenile idiopathic arthritis: Effect of route of administration on variability in intracellular methotrexate polyglutamate concentrations
- (2010) Mara L. Becker et al. ARTHRITIS AND RHEUMATISM
- Dosing in Children
- (2010) N Holford CLINICAL PHARMACOLOGY & THERAPEUTICS
- Understanding the Relative Roles of Pharmacogenetics and Ontogeny in Pediatric Drug Development and Regulatory Science
- (2010) J. Steven Leeder et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Efficacy, safety and pharmacokinetics of candesartan cilexetil in hypertensive children from 1 to less than 6 years of age
- (2010) Franz Schaefer et al. JOURNAL OF HYPERTENSION
- Understanding Developmental Pharmacodynamics
- (2010) Hussain Mulla PEDIATRIC DRUGS
- Assessment of Histamine Pharmacodynamics by Microvasculature Response of Histamine Using Histamine Iontophoresis Laser Doppler Flowimetry
- (2009) Bridgette L. Jones et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Characterization of delayed liquid gastric emptying in children by the13C-acetate breath test
- (2009) B L Jones et al. Journal of Breath Research
- Single time point diagnostic breath tests: a review
- (2009) Anil S Modak Journal of Breath Research
- Evaluation of a [13C]-Dextromethorphan Breath Test to Assess CYP2D6 Phenotype
- (2008) J. Steven Leeder et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Postmenstrual Age and CYP2D6 Polymorphisms Determine Tramadol O-demethylation in Critically Ill Neonates and Infants
- (2008) Karel Allegaert et al. PEDIATRIC RESEARCH
- The ontogeny of drug metabolism enzymes and implications for adverse drug events
- (2008) Ronald N. Hines PHARMACOLOGY & THERAPEUTICS
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