Anti-IL21 receptor monoclonal antibody (ATR-107): Safety, pharmacokinetics, and pharmacodynamic evaluation in healthy volunteers: A phase I, first-in-human study

pSTAT3: a target biomarker to study the pharmacology of the anti-IL-21R antibody ATR-107 in human whole blood

(2013) Ming Zhu et al.   Journal of Translational Medicine

IL-21 Receptor Is Required for the Systemic Accumulation of Activated B and T Lymphocytes in MRL/MpJ-Faslpr/lpr/J Mice

(2012) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

IL-21 Receptor Is Critical for the Development of Memory B Cell Responses

(2010) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

In vitro potency, pharmacokinetic profiles and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus

(2010) Yulia Vugmeyster et al.   mAbs

Interleukin 21 as a target of intervention in autoimmune disease

(2008) R Ettinger et al.   ANNALS OF THE RHEUMATIC DISEASES

The role of IL-21 in regulating B-cell function in health and disease

(2008) Rachel Ettinger et al.   IMMUNOLOGICAL REVIEWS

Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

(2007) Rosanne Spolski et al.   Annual Review of Immunology