Article
Dentistry, Oral Surgery & Medicine
Cristina Carral, Juan Flores-Guillen, Elena Figuero, Daniel Rodrigo, Ignacio Sanz-Sanchez, Juan Carlos Llodra, Manuel Bravo, Raul G. Caffesse, Nuria Vallcorba, Adrian Guerrero, Antonio Bujaldon, David Herrera
Summary: This study evaluated radiographic bone level (RxBL) at dental implants in Spain, finding significant associations between RxBL and clinical output variables as well as potential predictor variables such as smoking habits, implant diameter, years of follow-up, and type of prosthesis. Peri-implant RxBL ranged from 0 to 13.17 mm, demonstrating its importance in implant success and maintenance.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2021)
Review
Medicine, General & Internal
Andrea Roccuzzo, Alexandra Stahli, Alberto Monje, Anton Sculean, Giovanni E. Salvi
Summary: Dental implants are considered a reliable routine procedure for replacing missing teeth, but the presence of peri-implantitis has become a concern due to its negative impact on patients' quality of life. The surgical therapeutic modalities for managing this disorder include indications, contraindications, complexity, predictability, and effectiveness.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Dentistry, Oral Surgery & Medicine
Maria Vera Rodriguez, Andrea Ravida, Muhammad H. A. Saleh, Hussein S. Basma, Himabindu Dukka, Hadiya Khurshid, Hom-Lay Wang, Pablo Galindo Moreno
Summary: This retrospective study investigated the association between the amount of initial physiological bone remodeling (IPBR) during the first year of implant placement and the incidence of peri-implantitis as well as the pattern of progressive bone loss. The results showed no significant association between IPBR and peri-implantitis, but splinted implants had a higher marginal bone loss rate compared to non-splinted implants from T1 to T2.
JOURNAL OF PERIODONTOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Oded Heyman, Yael Horev, Gabriel Mizraji, Yaron Haviv, Lior Shapira, Asaf Wilensky
Summary: This study aimed to investigate the pathogenesis of peri-implantitis in mice and evaluate the efficacy of Resolvin D2 as a treatment modality. The results revealed that dental implants are susceptible to infection and associated with bone loss, but treatment with RvD2 can prevent the disease.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Medicine, General & Internal
Pablo Galindo-Moreno, Andres Catena, Lucia Lopez-Chaichio, Tiago Borges, Francisco O'Valle, Laura Torrecillas-Martinez, Miguel Padial-Molina
Summary: The aim of this study was to analyze the long-term marginal bone level (MBL) of implants supporting fixed full-arch restoration in patients who had previously lost their dentition due to severe periodontitis. The results showed that dental implants restored with fixed segmented full-arch rehabilitation in patients with a history of severe periodontal disease do not suffer important marginal bone loss if some specific factors are considered, mainly the use of long transmucosal abutments (>= 2 mm).
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, Research & Experimental
Carlos Henrique Alves, Karolayne Larissa Russi, Natalia Conceicao Rocha, Fabio Bastos, Michelle Darrieux, Thais Manzano Parisotto, Raquel Girardello
Summary: In recent decades, there have been significant advances in ortho-aesthetic-functional rehabilitation with the introduction of implantology. However, there is still a percentage of failures in implantology surgeries, mainly due to infections caused by bacterial proliferation, fungi presence, and biofilm formation, leading to peri-implantitis. Various studies have been conducted to explore the interaction between the host-oral microbiome and the development of peri-implantitis. Peri-implantitis is associated with a diversity of bacterial species, with Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia being identified in higher proportions of peri-implantitis samples. In addition, the injury of peri-implant tissue triggers an inflammatory response mediated by the activation of innate immune cells, such as macrophages, dendritic cells, mast cells, and neutrophils. Activation of the host immune system may disrupt the balance of oral microbiota, leading to dysbiosis and the production of various substances that contribute to implant loss.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Jad Majzoub, Zhaozhao Chen, Islam Saleh, Houssam Askar, Hom-Lay Wang
Summary: The restorative design factors like restoration emergence angle and maintenance visit frequency significantly influenced the early progression of peri-implantitis. 66.3% of implants exhibited marginal bone loss within 1mm of the apical end of the internal screw, indicating a common location for peri-implant bone loss.
JOURNAL OF PERIODONTOLOGY
(2021)
Review
Infectious Diseases
Asma Gasmi Benahmed, Amin Gasmi, Torsak Tippairote, Pavan Kumar Mujawdiya, Oleksandr Avdeev, Yurii Shanaida, Geir Bjorklund
Summary: Dental implants are commonly used to replace lost teeth, and titanium implants have a high success rate. However, there is an increasing risk of peri-implantitis, an inflammatory disease that affects the tissues around the implant. This review highlights the impact of different metabolic conditions on peri-implantitis and emphasizes the importance of considering both local and systemic factors in dental implant procedures and treatment.
Review
Biochemistry & Molecular Biology
Francesca Delucchi, Camilla Canepa, Luigi Canullo, Paolo Pesce, Gaetano Isola, Maria Menini
Summary: The aim of this systematic review is to summarize current knowledge on the use of biomarkers extracted from peri-implant crevicular fluid (PICF) as predictors of peri-implant bone loss (BL). A total of 158 entries were initially found, and after a full-text review and assessment of eligibility criteria, nine articles were selected. According to the review, several inflammatory biomarkers harvested from PICF seem to be correlated with peri-implant bone loss and may aid in diagnosing peri-implantitis early. MiRNA expression has shown predictive potential for peri-implant bone loss and may be useful for preventive and therapeutic purposes in implant dentistry.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Health Care Sciences & Services
Hsi-Kuei Lin, Jerry Chin-Yi Lin, Yu-Hwa Pan, Eisner Salamanca, Yi-Ting Chang, Yung-Szu Hsu, Yi-Fan Wu, Chin-Kai Lin, Odontuya Dorj, Wei-Jen Chang
Summary: Preserving marginal bone level is crucial for the success of dental implant therapy. This study found that platform-switching (PS) dental implants showed less reduction in marginal bone level compared to platform-matching (PM) dental implants, and had a positive impact on vertical and horizontal bone defects.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Gabriela Giro, Andressa Tebar, Leonardo Franco, Danilo Racy, Marta Ferreira Bastos, Jamil Awad Shibli
Summary: This study found higher gene expression levels of the transcription factors ROR gamma T and FOXP3 in tissues affected by peri-implantitis compared to healthy tissues, indicating a possible hybrid TH17-Treg profile. Further research is needed to better understand the immunological mechanisms involved in the pathogenesis of peri-implantitis.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Mario Romandini, Jessica Berglundh, Jan Derks, Mariano Sanz, Tord Berglundh
Summary: The study aimed to evaluate the diagnostic accuracy of clinical and radiographic evaluations made at a single time point during follow-up. The bone levels observed at 9 years were highly accurate in identifying pronounced bone loss. In the absence of baseline documentation, a secondary case definition based on clinical findings provided the best overall diagnostic accuracy in identifying peri-implantitis cases.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Article
Medicine, General & Internal
Pablo Galindo-Moreno, Ada Concha-Jeronimo, Lucia Lopez-Chaichio, Roque Rodriguez-Alvarez, Elena Sanchez-Fernandez, Miguel Padial-Molina
Summary: The study found that single-unit restorations with internal hexagonal-connection implants induce higher marginal bone loss after 12 months of follow-up from prosthesis delivery than internal conical-connection implants.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Chemistry, Multidisciplinary
Aslihan Secgin-Atar, Gokce Aykol-Sahin, Necla Asli Kocak-Oztug, Funda Yalcin, Aslan Gokbuget, Ulku Baser
Summary: The aim of the study was to restore similar surface properties and elemental composition to virgin implants after debridement of contaminated titanium implant surfaces covered with debris. Different debridement methods were applied, with Er:YAG long pulse and ultrasonic groups found to be the most effective in debridement and showing the closest topography to virgin implants.
Review
Dentistry, Oral Surgery & Medicine
Jovania Alves Oliveira, Roberta de Oliveira Alves, Isabella Mazarelo Nascimento, Marco Antonio Rimachi Hidalgo, Raquel Mantuaneli Scarel-Caminaga, Suzane Cristina Pigossi
Summary: This study aimed to review the levels of pro- and anti-inflammatory cytokines and osteoclastogenesis-related factors in peri-implant diseases. The results showed that the levels of IL-1β, IL-6, IL-10, and RANKL/OPG were not balanced in peri-implant diseases, suggesting their involvement in the host response related to peri-implantitis.
Review
Dentistry, Oral Surgery & Medicine
Cristiano Tomasi, Jean-Pierre Albouy, Dennis Schaller, Renata Camino Navarro, Jan Derks
Summary: The efficacy of implant-supported compared to tooth-supported full-arch prostheses was evaluated in patients with stage IV periodontitis. Observational studies showed that the 10-year estimates of tooth loss were lower than for implants, while the estimated loss of tooth- and implant-supported restorations at 10 years was similar. Additionally, technical complications were more prevalent in implant-supported compared to tooth-supported restorations.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Review
Dentistry, Oral Surgery & Medicine
Jan Derks, Yuki Ichioka, Carlotta Dionigi, Anna Trullenque-Eriksson, Jessica Berglundh, Cristiano Tomasi, Filippo Graziani
Summary: This study evaluated outcome measures, assessment methods, and analysis in clinical studies on the prevention and management of peri-implant mucositis and peri-implantitis. The results showed that probing pocket depth (PPD) and bleeding/suppuration on probing (BOP) were commonly reported measures, while composite outcomes, adverse events, and patient-reported outcomes were less frequently described.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Review
Dentistry, Oral Surgery & Medicine
Jan Derks, Yuki Ichioka, Carlotta Dionigi, Anna Trullenque-Eriksson, Jessica Berglundh, Cristiano Tomasi, Filippo Graziani
Summary: This study evaluated outcome measures, assessment methods, and analysis in clinical studies on the prevention and management of peri-implant mucositis and peri-implantitis. The findings showed that probing pocket depth and bleeding/suppuration on probing were commonly reported, while composite outcomes, adverse events, and patient-reported outcomes were infrequently described.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jan Derks, Alberto Ortiz-Vigon, Adrian Guerrero, Mauro Donati, Eriberto Bressan, Paolo Ghensi, Dennis Schaller, Cristiano Tomasi, Karolina Karlsson, Ingemar Abrahamsson, Yuki Ichioka, Carlotta Dionigi, Erik Regidor, Tord Berglundh
Summary: The study evaluated the potential benefits of using a bone substitute material in reconstructive surgical therapy for peri-implantitis. The results showed that surgical therapy effectively improved the clinical and radiographic status of patients, with high patient satisfaction.
CLINICAL ORAL IMPLANTS RESEARCH
(2022)
Review
Dentistry, Oral Surgery & Medicine
Karolina Karlsson, Anna Trullenque-Eriksson, Cristiano Tomasi, Jan Derks
Summary: Access flap and pocket elimination surgery are effective procedures in the management of peri-implantitis, as they can reduce probing depth and bleeding. However, treatment outcomes are influenced by baseline conditions and the recurrence rate of the disease is high within 5 years.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Eriberto Bressan, Riccardo Guazzo, Cristiano Tomasi, Teresa Gutierrez Pena, Pablo Galindo-Moreno, Vito Carlo Alberto Caponio, Luca Sbricoli, Luigi Canullo
Summary: The objective of this review and meta-analysis was to assess the impact of soft tissue thickness on initial bone remodeling after implant installation. A literature search was conducted, and 6 studies were included in the final analysis. The results showed that soft tissue thickness seemed to influence marginal bone loss after a short follow-up period. Further studies are needed to evaluate the influence of soft tissue thickness on marginal bone loss.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Rachel M. Thomson, Daniel Kopasker, Alastair Leyland, Anna Pearce, S. Vittal Katikireddi
Summary: This study estimated the effect of poverty on mental health using causal epidemiology. The results showed a significant absolute effect of poverty on the prevalence of common mental disorders in the UK working-age population, with larger effects observed in women. The population attributable fraction for moving into poverty was 6.34%, indicating that poverty contributes to a significant burden of mental health in this population.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Anna Trullenque-Eriksson, Cristiano Tomasi, Max Petzold, Tord Berglundh, Jan Derks
Summary: This registry-based retrospective cohort study found that furcation status has a significant impact on the risk for molar loss. Molars with furcation involvement of degree 2 and 3 have higher risk compared to those without furcation involvement. Additionally, endodontic status and probing depth are also relevant risk factors for molar loss.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Psychology, Educational
Claire Goodfellow, Malachi Willis, Joanna Inchley, Kalpa Kharicha, Alastair H. Leyland, Pamela Qualter, Sharon Simpson, Emily Long
Summary: Based on social-ecological theory, this study found that loneliness is associated with mental health, and this association varies in school settings. Loneliness, as well as demographic, social, and school factors, was found to be related to mental health. Furthermore, the negative impact of loneliness on mental health was stronger in schools with lower average mental health scores.
BRITISH JOURNAL OF EDUCATIONAL PSYCHOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Emily J. Tweed, Alastair H. Leyland, David S. Morrison, S. Vittal Katikireddi
Summary: This study used administrative data to conduct a unique population study of residents in Glasgow, Scotland, and found that experiences of social disadvantage are common. The study revealed that homelessness, justice involvement, opioid dependence, and psychosis are common forms of disadvantage, with the highest impact on men and residents in deprived areas. The study suggests that the methods used to analyze this data offer opportunities to evaluate the impact of policy and service changes on health.
EUROPEAN JOURNAL OF PUBLIC HEALTH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Lorenzo Marini, Cristiano Tomasi, Rodolfo Gianserra, Filippo Graziani, Luca Landi, Mauro Merli, Luigi Nibali, Mario Roccuzzo, Nicola M. Sforza, Maurizio S. Tonetti, Federico Deli, Piero Papi, Bianca Di Murro, Mariana A. Rojas, Andrea Pilloni
Summary: The purpose of this study was to evaluate the reliability and accuracy of assigning case definitions to dental implants according to the 2018 classification. The study found that the reliability and accuracy of the case definitions were mostly moderate.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Anna Simonelli, Roberto Farina, Luigi Minenna, Cristiano Tomasi, Leonardo Trombelli
Summary: This retrospective study evaluated the prognostic value of a composite outcome measure (COM) on clinical attachment level (CAL) change during a 4-year period of supportive periodontal care (SPC). The study found that COM can be used to predict CAL change at sites undergoing SPC following periodontal regenerative surgery.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Endocrinology & Metabolism
Renzo Flores-Ortiz, Rosemeire L. Fiaccone, Alastair Leyland, Christopher Millett, Thomas Hone, Maria Ines Schmidt, Andrea J. F. Ferreira, Maria Y. Ichihara, Camila Teixeira, Mauro N. Sanchez, Julia Pescarini, Estela M. L. Aquino, Deborah C. Malta, Gustavo Velasquez-Melendez, Juliane Fonseca de Oliveira, Peter Craig, Rita C. Ribeiro-Silva, Mauricio L. Barreto, Srinivasa Vittal Katikireddi
Summary: This study examined the association between subsidised housing residency and diabetes mortality among low-income adults in Brazil. The findings showed that subsidised housing residents had a higher risk of diabetes-related death, especially in low socioeconomic status municipalities.
BMJ OPEN DIABETES RESEARCH & CARE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Yuki Ichioka, Anna Trullenque-Eriksson, Alberto Ortiz-Vigon, Adrian Guerrero, Mauro Donati, Eriberto Bressan, Paolo Ghensi, Dennis Schaller, Cristiano Tomasi, Karolina Karlsson, Ingemar Abrahamsson, Carlotta Dionigi, Erik Regidor, Tord Berglundh, Jan Derks
Summary: This study aimed to identify predictors of treatment outcomes following surgical therapy of peri-implantitis. Baseline probing pocket depth (PPD) was found to be the most relevant predictor, showing positive associations with final PPD, soft-tissue recession (REC), and marginal bone level (MBL) gain, and negative association with probability of pocket closure. Smokers had higher residual PPD. Absence of keratinized mucosa at baseline increased the probability of bleeding on probing (BOP). Plaque at 6 weeks was detrimental in terms of residual PPD and BOP. Treatment allocation had an effect on REC. Final BOP was explained by residual PPD & GE;6 mm and plaque at more than two sites.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Jelena Milicev, Pamela Qualter, Claire Goodfellow, Joanna Inchley, Sharon Anne Simpson, Alastair H. Leyland, Kalpa Kharicha, Emily Long
Summary: This study examines the changes in mental wellbeing during the COVID-19 pandemic in the UK, focusing on loneliness, life satisfaction, and psychological distress. The results show significant interactions between these outcomes and the influence of individual, social, and environmental factors on the rates of change.
JOURNAL OF PUBLIC HEALTH-HEIDELBERG
(2023)
